Preliminary study on the effect of reduced graphene oxide, gold nanoparticles, and nafion® concentration on redox peak current for electrochemical biosensing

Electrochemical characterization of graphene-based nanocomposites as transducer nanomaterial for highly sensitive biosensors was performed. Parameters that were varied include graphene oxide (GO) concentration, amount of added gold nanoparticles (AuNPs), and Nafion® as binder for enhancing electrica...

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Main Authors:	Ismail, Nur Alya Batrisya, Arris, Farrah Aida, Tumian, Afidalina, Wan Salim, Wan Wardatul Amani
Format:	Article
Language:	English English English
Published:	Taylor's University 2019
Subjects:	TA164 Bioengineering TP250 Industrial electrochemistry
Online Access:	http://irep.iium.edu.my/70678/ http://irep.iium.edu.my/70678/ http://irep.iium.edu.my/70678/7/70678%20Preliminary%20study%20on%20the%20effect%20of%20reduced%20graphene%20oxide%2C%20gold%20nanoparticles.pdf http://irep.iium.edu.my/70678/8/70678%20Preliminary%20study%20on%20the%20effect%20of%20reduced%20graphene%20oxide%2C%20gold%20nanoparticles%20SCOPUS.pdf http://irep.iium.edu.my/70678/19/70678_PRELIMINARY%20STUDY%20ON%20THE%20EFFECT_wos.pdf

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recordtype	eprints
spelling	iium-706782019-07-12T08:02:20Z http://irep.iium.edu.my/70678/ Preliminary study on the effect of reduced graphene oxide, gold nanoparticles, and nafion® concentration on redox peak current for electrochemical biosensing Ismail, Nur Alya Batrisya Arris, Farrah Aida Tumian, Afidalina Wan Salim, Wan Wardatul Amani TA164 Bioengineering TP250 Industrial electrochemistry Electrochemical characterization of graphene-based nanocomposites as transducer nanomaterial for highly sensitive biosensors was performed. Parameters that were varied include graphene oxide (GO) concentration, amount of added gold nanoparticles (AuNPs), and Nafion® as binder for enhancing electrical conductivity of the transducer layer. The nanocomposite-modified glassy carbon electrode (GCE) transducer layers were fabricated via a simple two-step drop-cast and subsequent electrochemical reduction. Cyclic voltammetry (CV) was used to characterize the redox capability of the transducer layer. Electrochemical deposition of ultra-highly concentrated single-layer graphene oxide (UHC GO) suspension with a concentration of 6 mg/ml gave highest anodic peak current Ipa,, ~0.6 mA, after electrochemical reduction, compared to most peak currents reported in the literature for an electrode with an inner diameter of 3 mm; adding UHC GO:AuNPs in a 2:1 ratio followed by electrochemical reduction resulted in even higher Ipa (0.4 mA higher) in comparison to reduced UHC GO alone, whereas adding UHC GO:Nafion® in an 8:1 ratio shows a 1-mA increase in peak current. Therefore, AuNPs and Nafion® can be added to reduce UHC GO as nanocomposite for the development of a redox-active transducer that can result in highly sensitive biosensors. Taylor's University 2019-02 Article PeerReviewed application/pdf en http://irep.iium.edu.my/70678/7/70678%20Preliminary%20study%20on%20the%20effect%20of%20reduced%20graphene%20oxide%2C%20gold%20nanoparticles.pdf application/pdf en http://irep.iium.edu.my/70678/8/70678%20Preliminary%20study%20on%20the%20effect%20of%20reduced%20graphene%20oxide%2C%20gold%20nanoparticles%20SCOPUS.pdf application/pdf en http://irep.iium.edu.my/70678/19/70678_PRELIMINARY%20STUDY%20ON%20THE%20EFFECT_wos.pdf Ismail, Nur Alya Batrisya and Arris, Farrah Aida and Tumian, Afidalina and Wan Salim, Wan Wardatul Amani (2019) Preliminary study on the effect of reduced graphene oxide, gold nanoparticles, and nafion® concentration on redox peak current for electrochemical biosensing. Journal of Engineering Science and Technology (JESTEC), 14 (1). pp. 48-58. ISSN 1823-4690 http://jestec.taylors.edu.my/Vol%2014%20issue%201%20February%202019/14_1_04.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	TA164 Bioengineering TP250 Industrial electrochemistry
spellingShingle	TA164 Bioengineering TP250 Industrial electrochemistry Ismail, Nur Alya Batrisya Arris, Farrah Aida Tumian, Afidalina Wan Salim, Wan Wardatul Amani Preliminary study on the effect of reduced graphene oxide, gold nanoparticles, and nafion® concentration on redox peak current for electrochemical biosensing
description	Electrochemical characterization of graphene-based nanocomposites as transducer nanomaterial for highly sensitive biosensors was performed. Parameters that were varied include graphene oxide (GO) concentration, amount of added gold nanoparticles (AuNPs), and Nafion® as binder for enhancing electrical conductivity of the transducer layer. The nanocomposite-modified glassy carbon electrode (GCE) transducer layers were fabricated via a simple two-step drop-cast and subsequent electrochemical reduction. Cyclic voltammetry (CV) was used to characterize the redox capability of the transducer layer. Electrochemical deposition of ultra-highly concentrated single-layer graphene oxide (UHC GO) suspension with a concentration of 6 mg/ml gave highest anodic peak current Ipa,, ~0.6 mA, after electrochemical reduction, compared to most peak currents reported in the literature for an electrode with an inner diameter of 3 mm; adding UHC GO:AuNPs in a 2:1 ratio followed by electrochemical reduction resulted in even higher Ipa (0.4 mA higher) in comparison to reduced UHC GO alone, whereas adding UHC GO:Nafion® in an 8:1 ratio shows a 1-mA increase in peak current. Therefore, AuNPs and Nafion® can be added to reduce UHC GO as nanocomposite for the development of a redox-active transducer that can result in highly sensitive biosensors.
format	Article
author	Ismail, Nur Alya Batrisya Arris, Farrah Aida Tumian, Afidalina Wan Salim, Wan Wardatul Amani
author_facet	Ismail, Nur Alya Batrisya Arris, Farrah Aida Tumian, Afidalina Wan Salim, Wan Wardatul Amani
author_sort	Ismail, Nur Alya Batrisya
title	Preliminary study on the effect of reduced graphene oxide, gold nanoparticles, and nafion® concentration on redox peak current for electrochemical biosensing
title_short	Preliminary study on the effect of reduced graphene oxide, gold nanoparticles, and nafion® concentration on redox peak current for electrochemical biosensing
title_full	Preliminary study on the effect of reduced graphene oxide, gold nanoparticles, and nafion® concentration on redox peak current for electrochemical biosensing
title_fullStr	Preliminary study on the effect of reduced graphene oxide, gold nanoparticles, and nafion® concentration on redox peak current for electrochemical biosensing
title_full_unstemmed	Preliminary study on the effect of reduced graphene oxide, gold nanoparticles, and nafion® concentration on redox peak current for electrochemical biosensing
title_sort	preliminary study on the effect of reduced graphene oxide, gold nanoparticles, and nafion® concentration on redox peak current for electrochemical biosensing
publisher	Taylor's University
publishDate	2019
url	http://irep.iium.edu.my/70678/ http://irep.iium.edu.my/70678/ http://irep.iium.edu.my/70678/7/70678%20Preliminary%20study%20on%20the%20effect%20of%20reduced%20graphene%20oxide%2C%20gold%20nanoparticles.pdf http://irep.iium.edu.my/70678/8/70678%20Preliminary%20study%20on%20the%20effect%20of%20reduced%20graphene%20oxide%2C%20gold%20nanoparticles%20SCOPUS.pdf http://irep.iium.edu.my/70678/19/70678_PRELIMINARY%20STUDY%20ON%20THE%20EFFECT_wos.pdf
first_indexed	2023-09-18T21:40:21Z
last_indexed	2023-09-18T21:40:21Z
_version_	1777413097808461824

Preliminary study on the effect of reduced graphene oxide, gold nanoparticles, and nafion® concentration on redox peak current for electrochemical biosensing

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