Electrochemical methods to characterize nanomaterial-based transducers for the development of noninvasive glucose sensors

Electrochemical biosensors consist of electrodes modified with nanomaterials that contain immobilized biomolecules for analyte recognition and utilize electrochemical transduction; a glucose meter is an example of such a biosensor. Innovation in glucose monitoring includes non-invasive sensing, wher...

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Main Authors:	Ismail, Nur Alya Batrisya, Abd-Wahab, Firdaus, Bader, Mamoun M., Wan Salim, Wan Wardatul Amani
Format:	Book Chapter
Language:	English English
Published:	Springer International Publishing AG 2018
Subjects:	TA164 Bioengineering TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/70253/ http://irep.iium.edu.my/70253/ http://irep.iium.edu.my/70253/1/70253_Electrochemical%20methods%20to%20characterize.pdf http://irep.iium.edu.my/70253/7/70253_Electrochemical%20methods%20to%20characterize_Scopus.pdf

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recordtype	eprints
spelling	iium-702532020-03-06T01:33:21Z http://irep.iium.edu.my/70253/ Electrochemical methods to characterize nanomaterial-based transducers for the development of noninvasive glucose sensors Ismail, Nur Alya Batrisya Abd-Wahab, Firdaus Bader, Mamoun M. Wan Salim, Wan Wardatul Amani TA164 Bioengineering TP248.13 Biotechnology Electrochemical biosensors consist of electrodes modified with nanomaterials that contain immobilized biomolecules for analyte recognition and utilize electrochemical transduction; a glucose meter is an example of such a biosensor. Innovation in glucose monitoring includes non-invasive sensing, where alternative body fluids such as saliva can be used in place of blood, eliminating finger-pricking. However, the concentration of glucose in saliva is twofold lower than in blood, demanding a more sensitive transducer. For a decade, research focused on enhancing the transduction layer by modifying electrodes with nanomaterials that can increase electron transfer, enabling detection of glucose at much lower concentrations. The contribution of these nanomaterials towards enhancement of electron transfer can be understood via electrochemical characterization techniques such as cyclic voltammetry (CV), linear sweep voltammetry (LSV), and electrical impedance spectroscopy (EIS). This chapter provides the basis of the voltammetry techniques and EIS with example graphs from our current research. The aforementioned techniques were performed on screen-printed glassy carbon electrodes modified with reduced graphene–conductive polymer composites, with voltammetry measurements providing CV and LSV and EIS measurements, with EIS resulting in Bode and Nyquist plots and Randles equivalent circuit. Results from our study show a reversible electrode reaction that is diffusion controlled. Springer International Publishing AG 2018-12-14 Book Chapter PeerReviewed application/pdf en http://irep.iium.edu.my/70253/1/70253_Electrochemical%20methods%20to%20characterize.pdf application/pdf en http://irep.iium.edu.my/70253/7/70253_Electrochemical%20methods%20to%20characterize_Scopus.pdf Ismail, Nur Alya Batrisya and Abd-Wahab, Firdaus and Bader, Mamoun M. and Wan Salim, Wan Wardatul Amani (2018) Electrochemical methods to characterize nanomaterial-based transducers for the development of noninvasive glucose sensors. In: Nanotechnology: applications in energy, drug and food. Springer International Publishing AG, pp. 423-439. ISBN 978-3-319-99601-1 https://link.springer.com/chapter/10.1007/978-3-319-99602-8_20#citeas
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	TA164 Bioengineering TP248.13 Biotechnology
spellingShingle	TA164 Bioengineering TP248.13 Biotechnology Ismail, Nur Alya Batrisya Abd-Wahab, Firdaus Bader, Mamoun M. Wan Salim, Wan Wardatul Amani Electrochemical methods to characterize nanomaterial-based transducers for the development of noninvasive glucose sensors
description	Electrochemical biosensors consist of electrodes modified with nanomaterials that contain immobilized biomolecules for analyte recognition and utilize electrochemical transduction; a glucose meter is an example of such a biosensor. Innovation in glucose monitoring includes non-invasive sensing, where alternative body fluids such as saliva can be used in place of blood, eliminating finger-pricking. However, the concentration of glucose in saliva is twofold lower than in blood, demanding a more sensitive transducer. For a decade, research focused on enhancing the transduction layer by modifying electrodes with nanomaterials that can increase electron transfer, enabling detection of glucose at much lower concentrations. The contribution of these nanomaterials towards enhancement of electron transfer can be understood via electrochemical characterization techniques such as cyclic voltammetry (CV), linear sweep voltammetry (LSV), and electrical impedance spectroscopy (EIS). This chapter provides the basis of the voltammetry techniques and EIS with example graphs from our current research. The aforementioned techniques were performed on screen-printed glassy carbon electrodes modified with reduced graphene–conductive polymer composites, with voltammetry measurements providing CV and LSV and EIS measurements, with EIS resulting in Bode and Nyquist plots and Randles equivalent circuit. Results from our study show a reversible electrode reaction that is diffusion controlled.
format	Book Chapter
author	Ismail, Nur Alya Batrisya Abd-Wahab, Firdaus Bader, Mamoun M. Wan Salim, Wan Wardatul Amani
author_facet	Ismail, Nur Alya Batrisya Abd-Wahab, Firdaus Bader, Mamoun M. Wan Salim, Wan Wardatul Amani
author_sort	Ismail, Nur Alya Batrisya
title	Electrochemical methods to characterize nanomaterial-based transducers for the development of noninvasive glucose sensors
title_short	Electrochemical methods to characterize nanomaterial-based transducers for the development of noninvasive glucose sensors
title_full	Electrochemical methods to characterize nanomaterial-based transducers for the development of noninvasive glucose sensors
title_fullStr	Electrochemical methods to characterize nanomaterial-based transducers for the development of noninvasive glucose sensors
title_full_unstemmed	Electrochemical methods to characterize nanomaterial-based transducers for the development of noninvasive glucose sensors
title_sort	electrochemical methods to characterize nanomaterial-based transducers for the development of noninvasive glucose sensors
publisher	Springer International Publishing AG
publishDate	2018
url	http://irep.iium.edu.my/70253/ http://irep.iium.edu.my/70253/ http://irep.iium.edu.my/70253/1/70253_Electrochemical%20methods%20to%20characterize.pdf http://irep.iium.edu.my/70253/7/70253_Electrochemical%20methods%20to%20characterize_Scopus.pdf
first_indexed	2023-09-18T21:39:44Z
last_indexed	2023-09-18T21:39:44Z
_version_	1777413059394928640

Electrochemical methods to characterize nanomaterial-based transducers for the development of noninvasive glucose sensors

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