A clinical update on antibiotic resistance gram-negative bacteria in Malaysia-a review
Antibiotics are the wonder discoveries to combat microbes. For decades, multiple varieties of antibiotics have been used for therapeutic purposes in hospital settings and communities throughout the world. Unfortunately, bacteria have become resistant to commonly prescribed antibiotics. This review...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Editorial office of Journal of International Pharmaceutical Research
2018
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/70014/ http://irep.iium.edu.my/70014/1/70014_A%20clinical%20update%20on%20antibiotic%20resistance_article%20new.pdf http://irep.iium.edu.my/70014/2/70014_A%20clinical%20update%20on%20antibiotic%20resistance_scopus.pdf |
| Summary: | Antibiotics are the wonder discoveries to combat microbes. For decades, multiple varieties of antibiotics have been used for
therapeutic purposes in hospital settings and communities throughout the world. Unfortunately, bacteria have become
resistant to commonly prescribed antibiotics. This review aims to explore the development, challenges, and the current state
of antibiotic resistance available literature in Malaysia. Recently published data from Pubmed, Scopus, Google scholar’s
and other internet source publication on the antibiotic resistance of gram-negative bacteria were further reviewed and
analysed in this study. This review reiterates the antibiotic resistance among the gram-negative bacteria is increasing and
they are becoming resistant to nearly all groups of antibiotics. The antibiotic treatments are minimal and hard to treat in
multi-drug resistance bacterial infection, resulting in morbidity and mortality. The prevalence rate of antibiotic resistance
from the literature suggests that educating patients and the public is essential to prevent and control the spread of antibiotic
resistance. In particular, there is an urgent need for a surveillance system of regular monitoring on the microbiomes, the
discovery of novel antibiotics and therapeutic application of antibiotics are mandatory. |
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