Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum

Calophyllum is a pan-tropical genus belongs to the Guttiferae family and locally known in Malaysia as ‘bintangor’. There has been a continual interest to further investigate the phytochemistry of Calophyllum sp since this genus is a rich source of active secondary metabolites which showed anti-HIV,...

Full description

Bibliographic Details
Main Authors:	Aminudin, Nurul Iman, Ahmad, Farediah, Bakhtiar, M. Taher, Deny Susanti, Darnis
Format:	Conference or Workshop Item
Language:	English English English
Published:	2018
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/69563/ http://irep.iium.edu.my/69563/1/SKAM31%20PROGRAMME%20BOOK.pdf http://irep.iium.edu.my/69563/2/index.html http://irep.iium.edu.my/69563/8/69563.pdf

id	iium-69563
recordtype	eprints
spelling	iium-695632019-01-30T04:46:15Z http://irep.iium.edu.my/69563/ Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher Deny Susanti, Darnis QD Chemistry Calophyllum is a pan-tropical genus belongs to the Guttiferae family and locally known in Malaysia as ‘bintangor’. There has been a continual interest to further investigate the phytochemistry of Calophyllum sp since this genus is a rich source of active secondary metabolites which showed anti-HIV, cytotoxicity and antimicrobial properties. In this study, antibacterial and antioxidant activities of barks and leaves of C. ferrugineum and C. incrassatum were investigated. Cold extraction method employing dichloromethane, ethyl acetate and methanol as solvent was performed. All extracts were tested for their total phenolic content and antioxidant activities by DPPH radical scavenging and Ferric Reducing Antioxidant Power (FRAP) assays. The methanol extract from the leaves of C. ferrugineum showed the highest TPC value at 122.08 mg GAE/g and the lowest DPPH SC50 value at 11.80 µg/mL. The methanol extract from the barks of C. ferrugineum was found to have the highest FRAP value among all extracts. The antibacterial activity of all extracts was tested by minimum inhibition concentration (MIC) test against Bacillus subtilis, Staphylococcus aureus, Escheria coli and Pseudomonas aeruginosa. Only the dichloromethane extract from bark of C. ferrugineum showed moderate MIC value against Gram positive bacteria, B. subtilis and S. aureus at 125 µg/mL. 2018-08-17 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/69563/1/SKAM31%20PROGRAMME%20BOOK.pdf application/pdf en http://irep.iium.edu.my/69563/2/index.html application/pdf en http://irep.iium.edu.my/69563/8/69563.pdf Aminudin, Nurul Iman and Ahmad, Farediah and Bakhtiar, M. Taher and Deny Susanti, Darnis (2018) Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum. In: International Conference of Analytical Sciences (SKAM31), 17th-19th August 2018, Vistana Hotel, Kuantan, Pahang. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	QD Chemistry
spellingShingle	QD Chemistry Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher Deny Susanti, Darnis Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum
description	Calophyllum is a pan-tropical genus belongs to the Guttiferae family and locally known in Malaysia as ‘bintangor’. There has been a continual interest to further investigate the phytochemistry of Calophyllum sp since this genus is a rich source of active secondary metabolites which showed anti-HIV, cytotoxicity and antimicrobial properties. In this study, antibacterial and antioxidant activities of barks and leaves of C. ferrugineum and C. incrassatum were investigated. Cold extraction method employing dichloromethane, ethyl acetate and methanol as solvent was performed. All extracts were tested for their total phenolic content and antioxidant activities by DPPH radical scavenging and Ferric Reducing Antioxidant Power (FRAP) assays. The methanol extract from the leaves of C. ferrugineum showed the highest TPC value at 122.08 mg GAE/g and the lowest DPPH SC50 value at 11.80 µg/mL. The methanol extract from the barks of C. ferrugineum was found to have the highest FRAP value among all extracts. The antibacterial activity of all extracts was tested by minimum inhibition concentration (MIC) test against Bacillus subtilis, Staphylococcus aureus, Escheria coli and Pseudomonas aeruginosa. Only the dichloromethane extract from bark of C. ferrugineum showed moderate MIC value against Gram positive bacteria, B. subtilis and S. aureus at 125 µg/mL.
format	Conference or Workshop Item
author	Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher Deny Susanti, Darnis
author_facet	Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher Deny Susanti, Darnis
author_sort	Aminudin, Nurul Iman
title	Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum
title_short	Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum
title_full	Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum
title_fullStr	Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum
title_full_unstemmed	Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum
title_sort	antibacterial and antioxidant activities of extracts from calophyllum ferrugineum and calophyllum incrassatum
publishDate	2018
url	http://irep.iium.edu.my/69563/ http://irep.iium.edu.my/69563/1/SKAM31%20PROGRAMME%20BOOK.pdf http://irep.iium.edu.my/69563/2/index.html http://irep.iium.edu.my/69563/8/69563.pdf
first_indexed	2023-09-18T21:38:45Z
last_indexed	2023-09-18T21:38:45Z
_version_	1777412997568790528

Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum

Similar Items