Development of porous PCL-based microcarrier

Polycaprolactone (PCL) has been used for cell cultivation due to its biocompatibility. However, fabrication of porous PCL microcarrier was an obstacle and study of its biodegradability is also limited. In the present study, PCL-based porous microcarrier was fabricated with different parameters by us...

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Main Authors:	N.A. Halim, Muhammad Amirul, Hashim, Yumi Zuhanis Has-Yun, Samsudin, Nurhusna, Mohd Salleh, Hamzah
Format:	Article
Language:	English English
Published:	Insight Society 2018
Subjects:	TA164 Bioengineering
Online Access:	http://irep.iium.edu.my/69372/ http://irep.iium.edu.my/69372/ http://irep.iium.edu.my/69372/ http://irep.iium.edu.my/69372/1/69372_Development%20of%20porous%20PCL-based%20microcarrier.pdf http://irep.iium.edu.my/69372/2/69372_Development%20of%20porous%20PCL-based%20microcarrier_SCOPUS.pdf

id	iium-69372
recordtype	eprints
spelling	iium-693722019-10-18T03:12:19Z http://irep.iium.edu.my/69372/ Development of porous PCL-based microcarrier N.A. Halim, Muhammad Amirul Hashim, Yumi Zuhanis Has-Yun Samsudin, Nurhusna Mohd Salleh, Hamzah TA164 Bioengineering Polycaprolactone (PCL) has been used for cell cultivation due to its biocompatibility. However, fabrication of porous PCL microcarrier was an obstacle and study of its biodegradability is also limited. In the present study, PCL-based porous microcarrier was fabricated with different parameters by using emulsion evaporation method. From the study, at 20% camphene concentration, optimum pore size was generated which was at 11.738 μm. During the fabrication of the microcarrier, most of the parameters showed effect on the size of the microcarrier. Under the biodegradability test, it showed that the porous structure of the microcarrier enhance the degradation rate of the microcarrier. Throughout the study, all the parameters tested for the fabrication of microcarrier showed effect on it and the porous structure improve the degradation rate of PCL microcarrier. Insight Society 2018 Article PeerReviewed application/pdf en http://irep.iium.edu.my/69372/1/69372_Development%20of%20porous%20PCL-based%20microcarrier.pdf application/pdf en http://irep.iium.edu.my/69372/2/69372_Development%20of%20porous%20PCL-based%20microcarrier_SCOPUS.pdf N.A. Halim, Muhammad Amirul and Hashim, Yumi Zuhanis Has-Yun and Samsudin, Nurhusna and Mohd Salleh, Hamzah (2018) Development of porous PCL-based microcarrier. International Journal on Advanced Science, Engineering and Information Technology, 8 (4-2). pp. 1648-1653. ISSN 2088-5334 http://insightsociety.org/ojaseit/index.php/ijaseit/article/view/7037 http://dx.doi.org/10.18517/ijaseit.8.4-2.7037
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	TA164 Bioengineering
spellingShingle	TA164 Bioengineering N.A. Halim, Muhammad Amirul Hashim, Yumi Zuhanis Has-Yun Samsudin, Nurhusna Mohd Salleh, Hamzah Development of porous PCL-based microcarrier
description	Polycaprolactone (PCL) has been used for cell cultivation due to its biocompatibility. However, fabrication of porous PCL microcarrier was an obstacle and study of its biodegradability is also limited. In the present study, PCL-based porous microcarrier was fabricated with different parameters by using emulsion evaporation method. From the study, at 20% camphene concentration, optimum pore size was generated which was at 11.738 μm. During the fabrication of the microcarrier, most of the parameters showed effect on the size of the microcarrier. Under the biodegradability test, it showed that the porous structure of the microcarrier enhance the degradation rate of the microcarrier. Throughout the study, all the parameters tested for the fabrication of microcarrier showed effect on it and the porous structure improve the degradation rate of PCL microcarrier.
format	Article
author	N.A. Halim, Muhammad Amirul Hashim, Yumi Zuhanis Has-Yun Samsudin, Nurhusna Mohd Salleh, Hamzah
author_facet	N.A. Halim, Muhammad Amirul Hashim, Yumi Zuhanis Has-Yun Samsudin, Nurhusna Mohd Salleh, Hamzah
author_sort	N.A. Halim, Muhammad Amirul
title	Development of porous PCL-based microcarrier
title_short	Development of porous PCL-based microcarrier
title_full	Development of porous PCL-based microcarrier
title_fullStr	Development of porous PCL-based microcarrier
title_full_unstemmed	Development of porous PCL-based microcarrier
title_sort	development of porous pcl-based microcarrier
publisher	Insight Society
publishDate	2018
url	http://irep.iium.edu.my/69372/ http://irep.iium.edu.my/69372/ http://irep.iium.edu.my/69372/ http://irep.iium.edu.my/69372/1/69372_Development%20of%20porous%20PCL-based%20microcarrier.pdf http://irep.iium.edu.my/69372/2/69372_Development%20of%20porous%20PCL-based%20microcarrier_SCOPUS.pdf
first_indexed	2023-09-18T21:38:28Z
last_indexed	2023-09-18T21:38:28Z
_version_	1777412979753484288

Development of porous PCL-based microcarrier

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