Medical genetics in developing countries in the Asia-Pacific region: challenges and opportunities

Advances in genetic and genomic technology changed health-care services rapidly in low and middle income countries (LMICs) in the Asia-Pacific region. While genetic services were initially focused on population-based disease prevention strategies, they have evolved into clinic-based and therapeutics...

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Main Authors:	Thong, Meow Keong, See-Toh, Yiling, Hassan, Jamiyah, Syed Mohamed Ali, Jaffar
Format:	Article
Language:	English English English
Published:	Springer Nature 2018
Subjects:	H Social Sciences (General) HD72 Economic growth, development, planning Q Science (General) RB Pathology
Online Access:	http://irep.iium.edu.my/69084/ http://irep.iium.edu.my/69084/ http://irep.iium.edu.my/69084/ http://irep.iium.edu.my/69084/1/69084_Medical%20genetics%20in%20developing%20countries_article.pdf http://irep.iium.edu.my/69084/2/69084_Medical%20genetics%20in%20developing%20countries_scopus.pdf http://irep.iium.edu.my/69084/13/69084_Medical%20genetics%20in%20developing%20countries%20in%20the%20Asia-Pacific%20region%20challenges%20and%20opportunities_WOS.pdf

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recordtype	eprints
spelling	iium-690842019-07-15T01:58:03Z http://irep.iium.edu.my/69084/ Medical genetics in developing countries in the Asia-Pacific region: challenges and opportunities Thong, Meow Keong See-Toh, Yiling Hassan, Jamiyah Syed Mohamed Ali, Jaffar H Social Sciences (General) HD72 Economic growth, development, planning Q Science (General) RB Pathology Advances in genetic and genomic technology changed health-care services rapidly in low and middle income countries (LMICs) in the Asia-Pacific region. While genetic services were initially focused on population-based disease prevention strategies, they have evolved into clinic-based and therapeutics-oriented service. Many LMICs struggled with these noncommunicable diseases and were unprepared for the needs of a clinical genetic service. The emergence of a middle class population, the lack of regulatory oversight, and weak capacity-building in medical genetics expertise and genetic counseling services led to a range of genetic services of variable quality with minimal ethical oversight. Some of the current shortcomings faced include the lack of awareness of cultural values in genetic health care, the variable stages of socioeconomic development and educational background that led to increased demand and abuse of genetics, the role of women in society and the crisis of gender selection, the lack of preventive and care services for genetic and birth defects, the issues of gene ethics in medicine, and the lack of understanding of some religious controversies. These challenges provide opportunities for both developing and developed nations to work together to reduce the inequalities and to ensure a caring, inclusive, ethical, and cost-effective genetic service in the region. Springer Nature 2018-10-01 Article NonPeerReviewed application/pdf en http://irep.iium.edu.my/69084/1/69084_Medical%20genetics%20in%20developing%20countries_article.pdf application/pdf en http://irep.iium.edu.my/69084/2/69084_Medical%20genetics%20in%20developing%20countries_scopus.pdf application/pdf en http://irep.iium.edu.my/69084/13/69084_Medical%20genetics%20in%20developing%20countries%20in%20the%20Asia-Pacific%20region%20challenges%20and%20opportunities_WOS.pdf Thong, Meow Keong and See-Toh, Yiling and Hassan, Jamiyah and Syed Mohamed Ali, Jaffar (2018) Medical genetics in developing countries in the Asia-Pacific region: challenges and opportunities. Genetics in Medicine, 20 (10). pp. 1114-1121. ISSN 1098-3600 E-ISSN 1530-0366 https://www.nature.com/articles/s41436-018-0135-0 10.1038/s41436-018-0135-0
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	H Social Sciences (General) HD72 Economic growth, development, planning Q Science (General) RB Pathology
spellingShingle	H Social Sciences (General) HD72 Economic growth, development, planning Q Science (General) RB Pathology Thong, Meow Keong See-Toh, Yiling Hassan, Jamiyah Syed Mohamed Ali, Jaffar Medical genetics in developing countries in the Asia-Pacific region: challenges and opportunities
description	Advances in genetic and genomic technology changed health-care services rapidly in low and middle income countries (LMICs) in the Asia-Pacific region. While genetic services were initially focused on population-based disease prevention strategies, they have evolved into clinic-based and therapeutics-oriented service. Many LMICs struggled with these noncommunicable diseases and were unprepared for the needs of a clinical genetic service. The emergence of a middle class population, the lack of regulatory oversight, and weak capacity-building in medical genetics expertise and genetic counseling services led to a range of genetic services of variable quality with minimal ethical oversight. Some of the current shortcomings faced include the lack of awareness of cultural values in genetic health care, the variable stages of socioeconomic development and educational background that led to increased demand and abuse of genetics, the role of women in society and the crisis of gender selection, the lack of preventive and care services for genetic and birth defects, the issues of gene ethics in medicine, and the lack of understanding of some religious controversies. These challenges provide opportunities for both developing and developed nations to work together to reduce the inequalities and to ensure a caring, inclusive, ethical, and cost-effective genetic service in the region.
format	Article
author	Thong, Meow Keong See-Toh, Yiling Hassan, Jamiyah Syed Mohamed Ali, Jaffar
author_facet	Thong, Meow Keong See-Toh, Yiling Hassan, Jamiyah Syed Mohamed Ali, Jaffar
author_sort	Thong, Meow Keong
title	Medical genetics in developing countries in the Asia-Pacific region: challenges and opportunities
title_short	Medical genetics in developing countries in the Asia-Pacific region: challenges and opportunities
title_full	Medical genetics in developing countries in the Asia-Pacific region: challenges and opportunities
title_fullStr	Medical genetics in developing countries in the Asia-Pacific region: challenges and opportunities
title_full_unstemmed	Medical genetics in developing countries in the Asia-Pacific region: challenges and opportunities
title_sort	medical genetics in developing countries in the asia-pacific region: challenges and opportunities
publisher	Springer Nature
publishDate	2018
url	http://irep.iium.edu.my/69084/ http://irep.iium.edu.my/69084/ http://irep.iium.edu.my/69084/ http://irep.iium.edu.my/69084/1/69084_Medical%20genetics%20in%20developing%20countries_article.pdf http://irep.iium.edu.my/69084/2/69084_Medical%20genetics%20in%20developing%20countries_scopus.pdf http://irep.iium.edu.my/69084/13/69084_Medical%20genetics%20in%20developing%20countries%20in%20the%20Asia-Pacific%20region%20challenges%20and%20opportunities_WOS.pdf
first_indexed	2023-09-18T21:38:03Z
last_indexed	2023-09-18T21:38:03Z
_version_	1777412953161596928

Medical genetics in developing countries in the Asia-Pacific region: challenges and opportunities

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