Periodic assessment of antenatal and post natal serum endothelin-1 and nitric oxide levels in hypertensive disorders of pregnancy
Hypertensive Disorder of Pregnancy (HDP) is an independent risk factor of cardiovascular (CVS) disease with persistent endothelial dysfunction, that occurs after the initial insult during pregnancy and persists post partum postulated to be the pathophysiology. Endothelin-1 (ET-1), a potent vasoconst...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia
2018
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/68988/ http://irep.iium.edu.my/68988/ http://irep.iium.edu.my/68988/1/MRS2018-22%20Periodic%20Assessment%20Of%20Antenatal%20And%20Post%20Natal%20Serum%20Endothelin1%20and%20Nitric%20Oxide%20Levels%20In%20Hypertensive%20Disorders%20Of%20Pregnancy.pdf |
| Summary: | Hypertensive Disorder of Pregnancy (HDP) is an independent risk factor of cardiovascular (CVS) disease with persistent endothelial dysfunction, that occurs after the initial insult during pregnancy and persists post partum postulated to be the pathophysiology. Endothelin-1 (ET-1), a potent vasoconstrictor, has been
identified as a pivotal mediator in both essential hypertension and HDP. Disturbances in Nitric Oxide (NO) bioavailability found in endothelial dysfunction
may increase susceptibility to cardiovascular diseases such as hypertension. |
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