Localized erythematous pappular rash: a rare presentation of essential thrombocythemia

Essential thrombocythemia (ET) is one of the myeloproliferative neoplasms which typically presents with thrombotic vasomotor symptoms or bleeding tendencies. Papular rash is a rare manifestation of ET and may cause delay in making the diagnosis and hence institution of the treatment. We report a cas...

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Main Authors:	Shalihin, Mohd Shaiful Ehsan, Harun, Zulkifli, Osman, Iskandar Firzada
Format:	Article
Language:	English
Published:	Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia 2018
Subjects:	R Medicine (General) RA Public aspects of medicine RB Pathology RL Dermatology
Online Access:	http://irep.iium.edu.my/68983/ http://irep.iium.edu.my/68983/ http://irep.iium.edu.my/68983/1/MRS2018-88%20Localized%20erthematous%20pappular%20rash%20a%20rare%20presentation%20of%20essential%20thrombocythemia.pdf

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spelling	iium-689832019-01-08T07:18:21Z http://irep.iium.edu.my/68983/ Localized erythematous pappular rash: a rare presentation of essential thrombocythemia Shalihin, Mohd Shaiful Ehsan Harun, Zulkifli Osman, Iskandar Firzada R Medicine (General) RA Public aspects of medicine RB Pathology RL Dermatology Essential thrombocythemia (ET) is one of the myeloproliferative neoplasms which typically presents with thrombotic vasomotor symptoms or bleeding tendencies. Papular rash is a rare manifestation of ET and may cause delay in making the diagnosis and hence institution of the treatment. We report a case of ET in a 50- year-old gentleman, who presented with nonspecific localized erythematous papular rash over his right thigh associated with recurrent mild pain in the affected thigh for one year. He was not any drugs prior to the onset of the rash. He had no history suggestive of haematological disorder such as bleeding tendencies, recurrent fever or anaemic symptoms. He also had no constitutional symptoms or any palpable masses. He was managed conservatively initially at primary care clinic but the problem persisted. A full blood count was subsequently performed which revealed an isolated thrombocytosis of 880 x 109 /L. He was referred to the haematology team for the further management and a diagnosis of ET was then made. Both the platelet counts and the lesion improved with hydroxyurea treatment. This case report illustrates a rare chronic manifestation of myeloproliferative neoplasm detected at a primary care clinic. Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia 2018-12-14 Article PeerReviewed application/pdf en http://irep.iium.edu.my/68983/1/MRS2018-88%20Localized%20erthematous%20pappular%20rash%20a%20rare%20presentation%20of%20essential%20thrombocythemia.pdf Shalihin, Mohd Shaiful Ehsan and Harun, Zulkifli and Osman, Iskandar Firzada (2018) Localized erythematous pappular rash: a rare presentation of essential thrombocythemia. International Medical Journal Malaysia, 17 (Supplementary Issue No 1). p. 87. E-ISSN 1823-4631 http://iiumedic.net/imjm/v1/download/vol_17_no_3_supp_1/MRS2018-88.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General) RA Public aspects of medicine RB Pathology RL Dermatology
spellingShingle	R Medicine (General) RA Public aspects of medicine RB Pathology RL Dermatology Shalihin, Mohd Shaiful Ehsan Harun, Zulkifli Osman, Iskandar Firzada Localized erythematous pappular rash: a rare presentation of essential thrombocythemia
description	Essential thrombocythemia (ET) is one of the myeloproliferative neoplasms which typically presents with thrombotic vasomotor symptoms or bleeding tendencies. Papular rash is a rare manifestation of ET and may cause delay in making the diagnosis and hence institution of the treatment. We report a case of ET in a 50- year-old gentleman, who presented with nonspecific localized erythematous papular rash over his right thigh associated with recurrent mild pain in the affected thigh for one year. He was not any drugs prior to the onset of the rash. He had no history suggestive of haematological disorder such as bleeding tendencies, recurrent fever or anaemic symptoms. He also had no constitutional symptoms or any palpable masses. He was managed conservatively initially at primary care clinic but the problem persisted. A full blood count was subsequently performed which revealed an isolated thrombocytosis of 880 x 109 /L. He was referred to the haematology team for the further management and a diagnosis of ET was then made. Both the platelet counts and the lesion improved with hydroxyurea treatment. This case report illustrates a rare chronic manifestation of myeloproliferative neoplasm detected at a primary care clinic.
format	Article
author	Shalihin, Mohd Shaiful Ehsan Harun, Zulkifli Osman, Iskandar Firzada
author_facet	Shalihin, Mohd Shaiful Ehsan Harun, Zulkifli Osman, Iskandar Firzada
author_sort	Shalihin, Mohd Shaiful Ehsan
title	Localized erythematous pappular rash: a rare presentation of essential thrombocythemia
title_short	Localized erythematous pappular rash: a rare presentation of essential thrombocythemia
title_full	Localized erythematous pappular rash: a rare presentation of essential thrombocythemia
title_fullStr	Localized erythematous pappular rash: a rare presentation of essential thrombocythemia
title_full_unstemmed	Localized erythematous pappular rash: a rare presentation of essential thrombocythemia
title_sort	localized erythematous pappular rash: a rare presentation of essential thrombocythemia
publisher	Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia
publishDate	2018
url	http://irep.iium.edu.my/68983/ http://irep.iium.edu.my/68983/ http://irep.iium.edu.my/68983/1/MRS2018-88%20Localized%20erthematous%20pappular%20rash%20a%20rare%20presentation%20of%20essential%20thrombocythemia.pdf
first_indexed	2023-09-18T21:37:54Z
last_indexed	2023-09-18T21:37:54Z
_version_	1777412943766355968

Localized erythematous pappular rash: a rare presentation of essential thrombocythemia

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