Antifilarial potential of the fruits and leaves extracts of Pongamia pinnata on cattle filarial parasite Setaria cervi

The effect of aqueous and alcohol extracts of the fruits and leaves of Pongamia pinnata (Linn.) Merr. (Syn. Pongamia glabra Vent, leguminosae) on the spontaneous movements of both the whole worm and the nerve–muscle preparation of Setaria cervi and on the survival of microfilariae in vitro was studie...

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Main Authors: Ahmed, Qamar Uddin, Parveen, Nazneen, Khan, Nizam Ud Din, Singhal, Kavita C.
Format: Article
Language:English
Published: John Wiley & Sons Inc., USA. 2003
Subjects:
Online Access:http://irep.iium.edu.my/68939/
http://irep.iium.edu.my/68939/1/Uddin_et_al-2003-Phytotherapy_Research.pdf
id iium-68939
recordtype eprints
spelling iium-689392019-01-02T00:21:01Z http://irep.iium.edu.my/68939/ Antifilarial potential of the fruits and leaves extracts of Pongamia pinnata on cattle filarial parasite Setaria cervi Ahmed, Qamar Uddin Parveen, Nazneen Khan, Nizam Ud Din Singhal, Kavita C. Q Science (General) The effect of aqueous and alcohol extracts of the fruits and leaves of Pongamia pinnata (Linn.) Merr. (Syn. Pongamia glabra Vent, leguminosae) on the spontaneous movements of both the whole worm and the nerve–muscle preparation of Setaria cervi and on the survival of microfilariae in vitro was studied. The aqueous and alcohol extracts of fruits and the alcohol extract of leaves caused an inhibition of spontaneous movements of the whole worm and the nerve–muscle preparation of S. cervi. The initial stimulatory effect was not observed with the aqueous extract of fruits on the nerve–muscle preparation. The concentration required to inhibit the movements of the whole worm preparation was 250 µg/mL for aqueous, 120 µg/mL for alcohol extract of fruits and 270 µg/mL for alcohol extracts of the leaves. The concentrations of P. pinnata extracts required to produce an equivalent effect on the nerve–muscle preparation were 25 µg/mL, 5 µg/mL and 20 µg/mL, respectively, suggesting a cuticular permeability barrier. John Wiley & Sons Inc., USA. 2003 Article PeerReviewed application/pdf en http://irep.iium.edu.my/68939/1/Uddin_et_al-2003-Phytotherapy_Research.pdf Ahmed, Qamar Uddin and Parveen, Nazneen and Khan, Nizam Ud Din and Singhal, Kavita C. (2003) Antifilarial potential of the fruits and leaves extracts of Pongamia pinnata on cattle filarial parasite Setaria cervi. Phytotherapy Research, 17 (9). pp. 1104-1107. ISSN 0951-418X
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic Q Science (General)
spellingShingle Q Science (General)
Ahmed, Qamar Uddin
Parveen, Nazneen
Khan, Nizam Ud Din
Singhal, Kavita C.
Antifilarial potential of the fruits and leaves extracts of Pongamia pinnata on cattle filarial parasite Setaria cervi
description The effect of aqueous and alcohol extracts of the fruits and leaves of Pongamia pinnata (Linn.) Merr. (Syn. Pongamia glabra Vent, leguminosae) on the spontaneous movements of both the whole worm and the nerve–muscle preparation of Setaria cervi and on the survival of microfilariae in vitro was studied. The aqueous and alcohol extracts of fruits and the alcohol extract of leaves caused an inhibition of spontaneous movements of the whole worm and the nerve–muscle preparation of S. cervi. The initial stimulatory effect was not observed with the aqueous extract of fruits on the nerve–muscle preparation. The concentration required to inhibit the movements of the whole worm preparation was 250 µg/mL for aqueous, 120 µg/mL for alcohol extract of fruits and 270 µg/mL for alcohol extracts of the leaves. The concentrations of P. pinnata extracts required to produce an equivalent effect on the nerve–muscle preparation were 25 µg/mL, 5 µg/mL and 20 µg/mL, respectively, suggesting a cuticular permeability barrier.
format Article
author Ahmed, Qamar Uddin
Parveen, Nazneen
Khan, Nizam Ud Din
Singhal, Kavita C.
author_facet Ahmed, Qamar Uddin
Parveen, Nazneen
Khan, Nizam Ud Din
Singhal, Kavita C.
author_sort Ahmed, Qamar Uddin
title Antifilarial potential of the fruits and leaves extracts of Pongamia pinnata on cattle filarial parasite Setaria cervi
title_short Antifilarial potential of the fruits and leaves extracts of Pongamia pinnata on cattle filarial parasite Setaria cervi
title_full Antifilarial potential of the fruits and leaves extracts of Pongamia pinnata on cattle filarial parasite Setaria cervi
title_fullStr Antifilarial potential of the fruits and leaves extracts of Pongamia pinnata on cattle filarial parasite Setaria cervi
title_full_unstemmed Antifilarial potential of the fruits and leaves extracts of Pongamia pinnata on cattle filarial parasite Setaria cervi
title_sort antifilarial potential of the fruits and leaves extracts of pongamia pinnata on cattle filarial parasite setaria cervi
publisher John Wiley & Sons Inc., USA.
publishDate 2003
url http://irep.iium.edu.my/68939/
http://irep.iium.edu.my/68939/1/Uddin_et_al-2003-Phytotherapy_Research.pdf
first_indexed 2023-09-18T21:37:50Z
last_indexed 2023-09-18T21:37:50Z
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