A novel study of virgin coconut oil as an inhibitor against oral microbiata and its remineralisation potential on enamel tooth surface

As for today, dental caries has been reported adding to the significantly high number of oral health problem worldwide. Therefore, demands of alternatives for the classic regime in arresting issues related to oral health are always on the increase. The virgin coconut oil (VCO) is a case in point and...

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Main Author:	Abllah, Zurainie
Format:	Monograph
Language:	English
Published:	2018
Subjects:	RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
Online Access:	http://irep.iium.edu.my/68173/ http://irep.iium.edu.my/68173/1/Profile%20of%20Final%20Report-RAGS_dr%20zurainie.pdf

id	iium-68173
recordtype	eprints
spelling	iium-681732019-07-16T04:14:56Z http://irep.iium.edu.my/68173/ A novel study of virgin coconut oil as an inhibitor against oral microbiata and its remineralisation potential on enamel tooth surface Abllah, Zurainie RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works As for today, dental caries has been reported adding to the significantly high number of oral health problem worldwide. Therefore, demands of alternatives for the classic regime in arresting issues related to oral health are always on the increase. The virgin coconut oil (VCO) is a case in point and has been the focus for decades as it has proven to possess antimicrobial features on both Gram positive and Gram negative bacteria. Recently, there is a patented activated virgin coconut oil (AVCO) that has been reported to have a broad antimicrobial spectrum. However, information regarding the inhibitory of VCO and AVCO against dental caries-associated pathogens are yet lacking. There were four methods used to study the modes of action, which included time-killing assay, crystal violet assay, leakage of cellular materials and morphological analysis using Scanning Electron Microscopy (SEM). All of the tests were done in triplicate. The evaluation of FICI upon combination gives an antagonism and indifference effects. The study on the modes of actions revealed that AVCO was able to cause leakage of the cellular materials at 260 nm and 280 nm and increase cell permeability. Viewing of cells treated with AVCO by SEM showed some physical and morphological alterations indicating that AVCO able to disrupt the cell growth. These findings were able to backing the crucial role of AVCO as a potential antimicrobial agent, thus aid in arresting the problem of dental caries. 2018-11-30 Monograph NonPeerReviewed application/pdf en http://irep.iium.edu.my/68173/1/Profile%20of%20Final%20Report-RAGS_dr%20zurainie.pdf Abllah, Zurainie (2018) A novel study of virgin coconut oil as an inhibitor against oral microbiata and its remineralisation potential on enamel tooth surface. Project Report. UNSPECIFIED. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
spellingShingle	RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works Abllah, Zurainie A novel study of virgin coconut oil as an inhibitor against oral microbiata and its remineralisation potential on enamel tooth surface
description	As for today, dental caries has been reported adding to the significantly high number of oral health problem worldwide. Therefore, demands of alternatives for the classic regime in arresting issues related to oral health are always on the increase. The virgin coconut oil (VCO) is a case in point and has been the focus for decades as it has proven to possess antimicrobial features on both Gram positive and Gram negative bacteria. Recently, there is a patented activated virgin coconut oil (AVCO) that has been reported to have a broad antimicrobial spectrum. However, information regarding the inhibitory of VCO and AVCO against dental caries-associated pathogens are yet lacking. There were four methods used to study the modes of action, which included time-killing assay, crystal violet assay, leakage of cellular materials and morphological analysis using Scanning Electron Microscopy (SEM). All of the tests were done in triplicate. The evaluation of FICI upon combination gives an antagonism and indifference effects. The study on the modes of actions revealed that AVCO was able to cause leakage of the cellular materials at 260 nm and 280 nm and increase cell permeability. Viewing of cells treated with AVCO by SEM showed some physical and morphological alterations indicating that AVCO able to disrupt the cell growth. These findings were able to backing the crucial role of AVCO as a potential antimicrobial agent, thus aid in arresting the problem of dental caries.
format	Monograph
author	Abllah, Zurainie
author_facet	Abllah, Zurainie
author_sort	Abllah, Zurainie
title	A novel study of virgin coconut oil as an inhibitor against oral microbiata and its remineralisation potential on enamel tooth surface
title_short	A novel study of virgin coconut oil as an inhibitor against oral microbiata and its remineralisation potential on enamel tooth surface
title_full	A novel study of virgin coconut oil as an inhibitor against oral microbiata and its remineralisation potential on enamel tooth surface
title_fullStr	A novel study of virgin coconut oil as an inhibitor against oral microbiata and its remineralisation potential on enamel tooth surface
title_full_unstemmed	A novel study of virgin coconut oil as an inhibitor against oral microbiata and its remineralisation potential on enamel tooth surface
title_sort	novel study of virgin coconut oil as an inhibitor against oral microbiata and its remineralisation potential on enamel tooth surface
publishDate	2018
url	http://irep.iium.edu.my/68173/ http://irep.iium.edu.my/68173/1/Profile%20of%20Final%20Report-RAGS_dr%20zurainie.pdf
first_indexed	2023-09-18T21:36:46Z
last_indexed	2023-09-18T21:36:46Z
_version_	1777412872563851264

A novel study of virgin coconut oil as an inhibitor against oral microbiata and its remineralisation potential on enamel tooth surface

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