Formulation of dispersed gliclazide powder in polyethylene glycol–polyvinyl caprolactam– polyvinyl acetate grafted copolymer carrier for capsulation and improved dissolution
Background: Oral bioavailability of gliclazide, a hypoglycemic drug, is hindered by its low aqueous solubility. Improvement of solubility will enhance dissolution rate and in turn the bioavailability. This research aimed to formulate the solid dispersed gliclazide using a novel polyethylene glycol–p...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Association of Pharmaceutical Teachers of India
2018
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/67672/ http://irep.iium.edu.my/67672/ http://irep.iium.edu.my/67672/ http://irep.iium.edu.my/67672/1/IJPER_4_18-QC-RD.pdf |