Ethical responses to modern clinical trials on human subjects: a comparative perspective

With the modern advances and technological breakthroughs in biomedicine, scientific experiments involving human subjects had increased. Since the American gynecologist Marion Sims (d.1883), who conducted a scientific research on some selected African women suffering from prolapsed uterus disease,...

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Main Authors:	Hashi, Abdurezak Abdulahi, Abdul Razak, Tariq
Format:	Article
Language:	English English
Published:	Kulliyyah of Medicine and IIUM Press 2018
Subjects:	BJ1188 Religious ethics R Medicine (General)
Online Access:	http://irep.iium.edu.my/67478/ http://irep.iium.edu.my/67478/ http://irep.iium.edu.my/67478/1/Ethical%20Responses%20to%20Modern%20Clinical%20Trials%20on%20Human.pdf http://irep.iium.edu.my/67478/7/67478_Ethical%20responses%20to%20modern%20clinical%20trials%20on%20human_SCOPUS%202016.pdf

id	iium-67478
recordtype	eprints
spelling	iium-674782019-06-25T04:11:45Z http://irep.iium.edu.my/67478/ Ethical responses to modern clinical trials on human subjects: a comparative perspective Hashi, Abdurezak Abdulahi Abdul Razak, Tariq BJ1188 Religious ethics R Medicine (General) With the modern advances and technological breakthroughs in biomedicine, scientific experiments involving human subjects had increased. Since the American gynecologist Marion Sims (d.1883), who conducted a scientific research on some selected African women suffering from prolapsed uterus disease, or American physician Walter Reed’s (d.1902) team who gave germs of yellow fever to 22 human subjects to test if fever is transmitted by particularly mosquito species, as well as the Tuskegee Syphilis Study that was conducted from 1932 until 1972, or the scientific experiments conducted by Nazis of Germany on large numbers of prisoners, clinical trials on human subjects have become part of the scientific activities. These and many other scientific experiments conducted on human subjects had shown the extent of potential threats of unregulated scientific experiments on human life. Serious moral and legal concerns are then raised towards the morality of these activities. These concerns covered four major areas; safety, sanctity of the human body, consent and validity of experiment. This paper uses textual and analytical methods and aims to review Muslim jurists’ opinions on the permissibility of conducting clinical researches that uses human subjects. The opinions of the Muslim jurists are then compared to that of bioethical codes and declarations such as the Nuremberg Code, coined in (1947) and the Helsinki Declaration that was formulated by World Medical Organization in 1964. Fiqh and legal literature on this subject is exposed, and the moral contents of such writings are analyzed. The study is expected to come up with a comparative account of conventional and Islamic responses to modern clinical trials on human subjects. Kulliyyah of Medicine and IIUM Press 2018-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/67478/1/Ethical%20Responses%20to%20Modern%20Clinical%20Trials%20on%20Human.pdf application/pdf en http://irep.iium.edu.my/67478/7/67478_Ethical%20responses%20to%20modern%20clinical%20trials%20on%20human_SCOPUS%202016.pdf Hashi, Abdurezak Abdulahi and Abdul Razak, Tariq (2018) Ethical responses to modern clinical trials on human subjects: a comparative perspective. International Medical Journal of Malaysia, 17 (Special Issue ( No. 2)). pp. 213-218. E-ISSN 1823-4631 http://iiumedic.net/imjm/v1/download/volume_17_special_issue_2/Pages-from-2WCII-SI2-213_2.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	BJ1188 Religious ethics R Medicine (General)
spellingShingle	BJ1188 Religious ethics R Medicine (General) Hashi, Abdurezak Abdulahi Abdul Razak, Tariq Ethical responses to modern clinical trials on human subjects: a comparative perspective
description	With the modern advances and technological breakthroughs in biomedicine, scientific experiments involving human subjects had increased. Since the American gynecologist Marion Sims (d.1883), who conducted a scientific research on some selected African women suffering from prolapsed uterus disease, or American physician Walter Reed’s (d.1902) team who gave germs of yellow fever to 22 human subjects to test if fever is transmitted by particularly mosquito species, as well as the Tuskegee Syphilis Study that was conducted from 1932 until 1972, or the scientific experiments conducted by Nazis of Germany on large numbers of prisoners, clinical trials on human subjects have become part of the scientific activities. These and many other scientific experiments conducted on human subjects had shown the extent of potential threats of unregulated scientific experiments on human life. Serious moral and legal concerns are then raised towards the morality of these activities. These concerns covered four major areas; safety, sanctity of the human body, consent and validity of experiment. This paper uses textual and analytical methods and aims to review Muslim jurists’ opinions on the permissibility of conducting clinical researches that uses human subjects. The opinions of the Muslim jurists are then compared to that of bioethical codes and declarations such as the Nuremberg Code, coined in (1947) and the Helsinki Declaration that was formulated by World Medical Organization in 1964. Fiqh and legal literature on this subject is exposed, and the moral contents of such writings are analyzed. The study is expected to come up with a comparative account of conventional and Islamic responses to modern clinical trials on human subjects.
format	Article
author	Hashi, Abdurezak Abdulahi Abdul Razak, Tariq
author_facet	Hashi, Abdurezak Abdulahi Abdul Razak, Tariq
author_sort	Hashi, Abdurezak Abdulahi
title	Ethical responses to modern clinical trials on human subjects: a comparative perspective
title_short	Ethical responses to modern clinical trials on human subjects: a comparative perspective
title_full	Ethical responses to modern clinical trials on human subjects: a comparative perspective
title_fullStr	Ethical responses to modern clinical trials on human subjects: a comparative perspective
title_full_unstemmed	Ethical responses to modern clinical trials on human subjects: a comparative perspective
title_sort	ethical responses to modern clinical trials on human subjects: a comparative perspective
publisher	Kulliyyah of Medicine and IIUM Press
publishDate	2018
url	http://irep.iium.edu.my/67478/ http://irep.iium.edu.my/67478/ http://irep.iium.edu.my/67478/1/Ethical%20Responses%20to%20Modern%20Clinical%20Trials%20on%20Human.pdf http://irep.iium.edu.my/67478/7/67478_Ethical%20responses%20to%20modern%20clinical%20trials%20on%20human_SCOPUS%202016.pdf
first_indexed	2023-09-18T21:35:47Z
last_indexed	2023-09-18T21:35:47Z
_version_	1777412811294507008

Ethical responses to modern clinical trials on human subjects: a comparative perspective

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