Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves

—Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic...

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Main Authors:	Alara, Oluwaseun Ruth, Abdurahman, Nour Hamid, Abdul Mudalip, Siti Kholijah, Ukaegbu, Chinonso Ishmael, Azhari, Nour Hamid, Kabbashi, Nassereldeen Ahmed
Format:	Conference or Workshop Item
Language:	English
Published:	Faculty of Computer Systems & Software Engineering, Universiti Malaysia Pahang 2018
Subjects:	TP155 Chemical engineering
Online Access:	http://irep.iium.edu.my/67165/ http://irep.iium.edu.my/67165/ http://irep.iium.edu.my/67165/1/67165_Parametric%20Study%20of%20Soxhlet.pdf

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spelling	iium-671652018-10-31T03:40:43Z http://irep.iium.edu.my/67165/ Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Abdul Mudalip, Siti Kholijah Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed TP155 Chemical engineering —Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic content (TPC) and total flavonoid content (TFC) from extracts of Vernonia amygdalina leaves were investigated in this study using one-factor-at-a-time experiment (OFAT). Then,the functional group characterization of the extracts at maximum conditions was carried out. The results obtained showed that the three considered extraction parameters significantly influence the recoveries of extraction yield, TPC and TFC. Highest recoveries of extraction yield (14.22±0.19% w/w), TPC (75.94±2.15 mg GAE/g d.w.) and TFC (46.53±1.14 mg QE/g d.w.) were obtained at extraction time of 2 h, solid-to-solvent ratio of 1:20 g/mL and ethanol concentration of 60% v/v. Moreover, six major peaks were identified from the Soxhlet extraction of V. amygdalina leaves at maximum conditions using Fourier transform infrared spectroscopy (FTIR) analysis. Thus, this study showed that V. amygdalina leaf is a potential source of phenolic compounds which can be influence by the extraction parameters. Faculty of Computer Systems & Software Engineering, Universiti Malaysia Pahang 2018-08-28 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/67165/1/67165_Parametric%20Study%20of%20Soxhlet.pdf Alara, Oluwaseun Ruth and Abdurahman, Nour Hamid and Abdul Mudalip, Siti Kholijah and Ukaegbu, Chinonso Ishmael and Azhari, Nour Hamid and Kabbashi, Nassereldeen Ahmed (2018) Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves. In: National Conference for Postgraduate Research 2018 (NCONPGR 2018), 28th-29th Aug. 2018, Kuantan, Pahang. http://ncon-pgr.ump.edu.my/index.php/en/download/proceedings-book/file
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	TP155 Chemical engineering
spellingShingle	TP155 Chemical engineering Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Abdul Mudalip, Siti Kholijah Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
description	—Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic content (TPC) and total flavonoid content (TFC) from extracts of Vernonia amygdalina leaves were investigated in this study using one-factor-at-a-time experiment (OFAT). Then,the functional group characterization of the extracts at maximum conditions was carried out. The results obtained showed that the three considered extraction parameters significantly influence the recoveries of extraction yield, TPC and TFC. Highest recoveries of extraction yield (14.22±0.19% w/w), TPC (75.94±2.15 mg GAE/g d.w.) and TFC (46.53±1.14 mg QE/g d.w.) were obtained at extraction time of 2 h, solid-to-solvent ratio of 1:20 g/mL and ethanol concentration of 60% v/v. Moreover, six major peaks were identified from the Soxhlet extraction of V. amygdalina leaves at maximum conditions using Fourier transform infrared spectroscopy (FTIR) analysis. Thus, this study showed that V. amygdalina leaf is a potential source of phenolic compounds which can be influence by the extraction parameters.
format	Conference or Workshop Item
author	Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Abdul Mudalip, Siti Kholijah Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed
author_facet	Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Abdul Mudalip, Siti Kholijah Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed
author_sort	Alara, Oluwaseun Ruth
title	Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
title_short	Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
title_full	Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
title_fullStr	Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
title_full_unstemmed	Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
title_sort	parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
publisher	Faculty of Computer Systems & Software Engineering, Universiti Malaysia Pahang
publishDate	2018
url	http://irep.iium.edu.my/67165/ http://irep.iium.edu.my/67165/ http://irep.iium.edu.my/67165/1/67165_Parametric%20Study%20of%20Soxhlet.pdf
first_indexed	2023-09-18T21:35:21Z
last_indexed	2023-09-18T21:35:21Z
_version_	1777412784261169152

Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves

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