Serum Adiponectin status as a Biomarker of metabolic syndrome among Malaysians

Adiponectin is a collagen-like circulating protein secreted by adipocytes. Several studies have demonstrated that low adiponectin also has strong association with metabolic syndrome components such as it is decreased in obesity, insulin resistance, type 2 diabetes, dyslipidemia and coronary artery d...

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Main Authors:	Md Aris, Mohd Aznan, Draman, Samsul, Abdullah, Nor Zamzila, Mohd Rus, Razman, Khattak, Muhammad Muzaffar Ali Khan
Format:	Conference or Workshop Item
Language:	English
Published:	2011
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/6709/ http://irep.iium.edu.my/6709/ http://irep.iium.edu.my/6709/1/IRIIE_2011.pdf

id	iium-6709
recordtype	eprints
spelling	iium-67092011-12-23T06:57:26Z http://irep.iium.edu.my/6709/ Serum Adiponectin status as a Biomarker of metabolic syndrome among Malaysians Md Aris, Mohd Aznan Draman, Samsul Abdullah, Nor Zamzila Mohd Rus, Razman Khattak, Muhammad Muzaffar Ali Khan R Medicine (General) Adiponectin is a collagen-like circulating protein secreted by adipocytes. Several studies have demonstrated that low adiponectin also has strong association with metabolic syndrome components such as it is decreased in obesity, insulin resistance, type 2 diabetes, dyslipidemia and coronary artery disease. The objective of this study was to determine and compare the level of adiponectin between metabolic syndrome and non-metabolic syndrome subjects. A cross-sectional comparative study was carried out among 76 participants of metabolic syndrome and 76 participants of non metabolic syndrome based on IDF criteria. This study was held at three primary care clinics and two villages in Kuantan, Pahang from 1st March to 30th September 2009. The majority of respondents were Malay (88.8%) and female (57.9%) adult with mean age of 51 years old. Most of them are non-smoker (77.6%) and had history of Hypertension (51%) and Diabetes Mellitus (46.4%) with mean waist circumference of 88.5 cm and mean weight of 66.6kg. The study revealed that age, weight, waist circumference, blood pressure, fasting glucose, HDL-Cholesterol and triglycerides were significantly different in both group (P<0.05). The metabolic syndrome group had a significantly lower adiponectin concentration than non-metabolic syndrome group (mean: 11.64 ug/ml vs 13.21 ug/ml; P<0.05). Hence, this study concluded that serum adiponectin was a significant biomarker for metabolic syndrome. 2011-02-09 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/6709/1/IRIIE_2011.pdf Md Aris, Mohd Aznan and Draman, Samsul and Abdullah, Nor Zamzila and Mohd Rus, Razman and Khattak, Muhammad Muzaffar Ali Khan (2011) Serum Adiponectin status as a Biomarker of metabolic syndrome among Malaysians. In: IIUM Research, Invention and Innovation Exhibition (IRIIE) 2011, 9-10 February 2011, Cultural Activity Centre (CAC) and KAED Gallery IIUM. (Unpublished) http://www.iium.edu.my/irie/11/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Md Aris, Mohd Aznan Draman, Samsul Abdullah, Nor Zamzila Mohd Rus, Razman Khattak, Muhammad Muzaffar Ali Khan Serum Adiponectin status as a Biomarker of metabolic syndrome among Malaysians
description	Adiponectin is a collagen-like circulating protein secreted by adipocytes. Several studies have demonstrated that low adiponectin also has strong association with metabolic syndrome components such as it is decreased in obesity, insulin resistance, type 2 diabetes, dyslipidemia and coronary artery disease. The objective of this study was to determine and compare the level of adiponectin between metabolic syndrome and non-metabolic syndrome subjects. A cross-sectional comparative study was carried out among 76 participants of metabolic syndrome and 76 participants of non metabolic syndrome based on IDF criteria. This study was held at three primary care clinics and two villages in Kuantan, Pahang from 1st March to 30th September 2009. The majority of respondents were Malay (88.8%) and female (57.9%) adult with mean age of 51 years old. Most of them are non-smoker (77.6%) and had history of Hypertension (51%) and Diabetes Mellitus (46.4%) with mean waist circumference of 88.5 cm and mean weight of 66.6kg. The study revealed that age, weight, waist circumference, blood pressure, fasting glucose, HDL-Cholesterol and triglycerides were significantly different in both group (P<0.05). The metabolic syndrome group had a significantly lower adiponectin concentration than non-metabolic syndrome group (mean: 11.64 ug/ml vs 13.21 ug/ml; P<0.05). Hence, this study concluded that serum adiponectin was a significant biomarker for metabolic syndrome.
format	Conference or Workshop Item
author	Md Aris, Mohd Aznan Draman, Samsul Abdullah, Nor Zamzila Mohd Rus, Razman Khattak, Muhammad Muzaffar Ali Khan
author_facet	Md Aris, Mohd Aznan Draman, Samsul Abdullah, Nor Zamzila Mohd Rus, Razman Khattak, Muhammad Muzaffar Ali Khan
author_sort	Md Aris, Mohd Aznan
title	Serum Adiponectin status as a Biomarker of metabolic syndrome among Malaysians
title_short	Serum Adiponectin status as a Biomarker of metabolic syndrome among Malaysians
title_full	Serum Adiponectin status as a Biomarker of metabolic syndrome among Malaysians
title_fullStr	Serum Adiponectin status as a Biomarker of metabolic syndrome among Malaysians
title_full_unstemmed	Serum Adiponectin status as a Biomarker of metabolic syndrome among Malaysians
title_sort	serum adiponectin status as a biomarker of metabolic syndrome among malaysians
publishDate	2011
url	http://irep.iium.edu.my/6709/ http://irep.iium.edu.my/6709/ http://irep.iium.edu.my/6709/1/IRIIE_2011.pdf
first_indexed	2023-09-18T20:15:49Z
last_indexed	2023-09-18T20:15:49Z
_version_	1777407779745562624

Serum Adiponectin status as a Biomarker of metabolic syndrome among Malaysians

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