GC- MS analysis, phytochemical screening, antimicrobial and antioxidant activity of Sudanese annona squmosa seeds oil
The present research was including the phytochemical screening of Annona squmosa seeds in Sudan. Seed samples of Annona squmosa were selected. The objective of this the study was to examine the chemical constituent’s oil of Annona squmosa seeds, Sudan and to assess its potential antibacterial and a...
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IIUM Press, International Islamic University Malaysia
2018
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iium-669342018-10-24T07:44:07Z http://irep.iium.edu.my/66934/ GC- MS analysis, phytochemical screening, antimicrobial and antioxidant activity of Sudanese annona squmosa seeds oil Hajer, Tuhami Mirghani, Mohamed Elwathig Saeed Mohamed Elnour, Ahmed Adam Almain, Abdelrahman Ahmed Mohammed, Manhal Musa Mohammed Q Science (General) The present research was including the phytochemical screening of Annona squmosa seeds in Sudan. Seed samples of Annona squmosa were selected. The objective of this the study was to examine the chemical constituent’s oil of Annona squmosa seeds, Sudan and to assess its potential antibacterial and antioxidant activity. The Oil of Sudanese Annona squmosa seeds were extracted with n-hexane using Soxhlet extractor. Twenty-one components were detected by GC-MS analysis the major constituents are: Hexadecanoic acid (18.48), Heptadecanoic acid Methyl margarate (1.32) (C18H36O2), Heptadecanoic acid Methyl margarate (1.32), 9,12- octadecadienoic acid (Z,Z) (19.29% ), 9 - octadecenoic acid (Z) (34.01%), Methyl stearate (17.12%), Cis-11-Eicosenoic acid (1.14 ) and Eicosanoic acid (3.28% . the results showed that Alkaloids, Flavonoid, Carbohydrate, Saponins, Triterpene, Streol, Tannins and phenolic compounds were present in seeds of the Annona squmosa. According to DPPH assay, the data of oil showed the moderate antioxidant potential (50 ±0.09 compared with standard 93± 0.01). The antibacterial activity of the oil was evaluated by paper disc diffusion assay against six standard human pathogens (Gram-positive Staphylococcus aureus and Bacillus subtilis; Gram-negative: Escherichia coli and Pseudomonas aeruginosa), however, the oil was high activity against Escherichia coli, Bacillus subtilis and Candida albicans organism. The results indicated that oil of none squmosa seeds is a good source of antioxidants due to the presence of phenolic compounds, flavonoids. Also, an excellent source of natural antibacterial and this justify its uses in folkloric medicines. IIUM Press, International Islamic University Malaysia 2018-09-19 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/66934/1/66934_GC-%20MS%20Analysis%2C%20Phytochemical%20Screening.pdf application/pdf en http://irep.iium.edu.my/66934/2/66934_GC-%20MS%20Analysis%2C%20Phytochemical%20Screening-ppt.pdf Hajer, Tuhami and Mirghani, Mohamed Elwathig Saeed and Mohamed Elnour, Ahmed Adam and Almain, Abdelrahman Ahmed and Mohammed, Manhal Musa Mohammed (2018) GC- MS analysis, phytochemical screening, antimicrobial and antioxidant activity of Sudanese annona squmosa seeds oil. In: 5th International Conference on Biotechnology Engineering (ICBioE 2018), 19th-20th September 2018, Kuala Lumpur. http://www.iium.edu.my/icbioe/2018/ 42 |
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Q Science (General) Hajer, Tuhami Mirghani, Mohamed Elwathig Saeed Mohamed Elnour, Ahmed Adam Almain, Abdelrahman Ahmed Mohammed, Manhal Musa Mohammed GC- MS analysis, phytochemical screening, antimicrobial and antioxidant activity of Sudanese annona squmosa seeds oil |
description |
The present research was including the phytochemical screening of Annona squmosa seeds in Sudan. Seed
samples of Annona squmosa were selected. The objective of this the study was to examine the chemical constituent’s oil of Annona squmosa seeds, Sudan and to assess its potential antibacterial and antioxidant activity. The Oil of Sudanese Annona squmosa seeds were extracted with n-hexane using Soxhlet extractor. Twenty-one components were detected by GC-MS analysis the major constituents are: Hexadecanoic acid (18.48), Heptadecanoic acid Methyl margarate (1.32) (C18H36O2), Heptadecanoic acid Methyl margarate (1.32), 9,12- octadecadienoic acid (Z,Z) (19.29% ), 9 - octadecenoic acid (Z) (34.01%), Methyl stearate (17.12%), Cis-11-Eicosenoic acid (1.14 ) and Eicosanoic acid (3.28% . the results showed that Alkaloids, Flavonoid, Carbohydrate, Saponins, Triterpene, Streol, Tannins and phenolic compounds were present in seeds of the Annona squmosa. According to DPPH assay, the data of oil showed the moderate antioxidant potential (50 ±0.09 compared with standard 93± 0.01). The antibacterial activity of the oil was evaluated by paper disc
diffusion assay against six standard human pathogens (Gram-positive Staphylococcus aureus and Bacillus
subtilis; Gram-negative: Escherichia coli and Pseudomonas aeruginosa), however, the oil was high activity
against Escherichia coli, Bacillus subtilis and Candida albicans organism. The results indicated that oil of none
squmosa seeds is a good source of antioxidants due to the presence of phenolic compounds, flavonoids. Also, an
excellent source of natural antibacterial and this justify its uses in folkloric medicines. |
format |
Conference or Workshop Item |
author |
Hajer, Tuhami Mirghani, Mohamed Elwathig Saeed Mohamed Elnour, Ahmed Adam Almain, Abdelrahman Ahmed Mohammed, Manhal Musa Mohammed |
author_facet |
Hajer, Tuhami Mirghani, Mohamed Elwathig Saeed Mohamed Elnour, Ahmed Adam Almain, Abdelrahman Ahmed Mohammed, Manhal Musa Mohammed |
author_sort |
Hajer, Tuhami |
title |
GC- MS analysis, phytochemical screening, antimicrobial and antioxidant activity of Sudanese annona squmosa seeds oil |
title_short |
GC- MS analysis, phytochemical screening, antimicrobial and antioxidant activity of Sudanese annona squmosa seeds oil |
title_full |
GC- MS analysis, phytochemical screening, antimicrobial and antioxidant activity of Sudanese annona squmosa seeds oil |
title_fullStr |
GC- MS analysis, phytochemical screening, antimicrobial and antioxidant activity of Sudanese annona squmosa seeds oil |
title_full_unstemmed |
GC- MS analysis, phytochemical screening, antimicrobial and antioxidant activity of Sudanese annona squmosa seeds oil |
title_sort |
gc- ms analysis, phytochemical screening, antimicrobial and antioxidant activity of sudanese annona squmosa seeds oil |
publisher |
IIUM Press, International Islamic University Malaysia |
publishDate |
2018 |
url |
http://irep.iium.edu.my/66934/ http://irep.iium.edu.my/66934/ http://irep.iium.edu.my/66934/ http://irep.iium.edu.my/66934/1/66934_GC-%20MS%20Analysis%2C%20Phytochemical%20Screening.pdf http://irep.iium.edu.my/66934/2/66934_GC-%20MS%20Analysis%2C%20Phytochemical%20Screening-ppt.pdf |
first_indexed |
2023-09-18T21:35:02Z |
last_indexed |
2023-09-18T21:35:02Z |
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