Characterization of α-glucosidase inhibitors from clinacanthus nutans lindau Llaves by gas chromatography-mass spectrometry-based metabolomics and molecular docking simulation

Characterization of α-glucosidase inhibitors from clinacanthus nutans lindau Llaves by gas chromatography-mass spectrometry-based metabolomics and molecular docking simulation

Background: Clinacanthus nutans (C. nutans) is an Acanthaceae herbal shrub traditionally consumed to treat various diseases including diabetes in Malaysia. This study was designed to evaluate the α-glucosidase inhibitory activity of C. nutans leaves extracts, and to identify the metabolites responsi...

Full description

Bibliographic Details
Main Authors:	Murugesu, Suganya, Ibrahim, Zalikha, Ahmed, Qamar Uddin, Nik Yusoff, Nik Mohd. Idris, Uzir, Bisha Fathamah, Perumal, Vikneswari, Abas, Faridah, Saari, Khozirah, El-Seedi, Hesham, Khatib, Alfi
Format:	Article
Language:	English English
Published:	MDPI 2018
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/66730/ http://irep.iium.edu.my/66730/ http://irep.iium.edu.my/66730/ http://irep.iium.edu.my/66730/7/66730%20Characterization%20of%20%CE%B1-Glucosidase.pdf http://irep.iium.edu.my/66730/8/66730%20Characterization%20of%20%CE%B1-Glucosidase%20SCOPUS.pdf

Similar Items

Antidiabetic and antioxidants activities of Clinacanthus nutans (Burm F.) Lindau leaves extracts
by: Murugesu, Suganya, et al.
Published: (2019)

Identification of α-glucosidase inhibitors from Clinacanthus nutans leaf extract using liquid chromatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking
by: Murugesu, Suganya, et al.
Published: (2019)

Identiﬁcation of α-glucosidase inhibitors from Clinacanthus nutans leaf extract using liquid chromatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking
by: Murugesu, Suganya, et al.
Published: (2019)

Rapid investigation of α-glucosidase inhibitory activity of Clinacanthus nutans leaf using infrared fingerprinting
by: Murugesu, Suganya, et al.
Published: (2019)

Bioassays activity and FT-IR analysis of clinacanthus nutans (Burm F.) lindau leaves extracts
by: Khatib, Alfi, et al.
Published: (2017)

Toxicity study on Clinacanthus nutans leaf hexane fraction using Danio rerio embryos
by: Murugesu, Suganya, et al.
Published: (2019)

Low inhibition of alpha-glucosidase and xanthine oxidase activities of ethanol extract of Momordica charantia fruit
by: Khatib, Alfi, et al.
Published: (2017)

Ultrasonic extraction of Clinacanthus nutans and its antioxidant activity
by: Nik Fatima, Nek Kamarzaman
Published: (2013)

In vitro antioxidant and, α-glucosidase inhibitory activities and comprehensive metabolite profiling of methanol extract and its fractions from Clinacanthus nutans
by: Alam, Md. Ariful, et al.
Published: (2017)

A review of anticancer, antitumor, and antioxidant of clinacanthus nutans
by: Zakaria, Khairun Najwa, et al.
Published: (2017)

A review on anticancer and biochemical properties of Clinacanthus nutans
by: Zakaria, Khairun Najwa, et al.
Published: (2016)

Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
by: Alam, Md Ariful, et al.
Published: (2016)

In vitro cytotoxicity of Clinacanthus nutans fractions on breast cancer cells and molecular docking study of sulphur containing compounds against caspase-3
by: Roziasyahira, Mutazah, et al.
Published: (2020)

Evaluation of antioxidants activity of Momordica charantia using LC-MS metabolomics approach
by: Perumal, Vikneswari, et al.
Published: (2017)

Pharmacological activities and comprehensive metabolite profiling of Clinacanthus nutans extract and fractions
by: Alam, Md. Ariful, et al.
Published: (2016)

Extraction of protocatechuic acid enriched fraction from Clinacanthus nutans leaves
by: Zamery, Muhammad 'Izzuddin, et al.
Published: (2017)

Fabrication of face cream containing enriched fraction of protocatechuic acid from Clinacanthus nutans (C. Nutans) leaves
by: Zamery, Muhammad 'Izzuddin, et al.
Published: (2017)

Phytochemical diversity of Clinacanthus nutans extracts and their bioactivity correlations elucidated by NMR based metabolomics
by: Leng, Wei Khoo, et al.
Published: (2015)

Characterization of antioxidant activity of Momordica Charantia fruit by infrared-based fingerprinting
by: Khatib, Alfi, et al.
Published: (2017)

Bioassay-guided Isolation and Antioxidant Activity of Sulfur-containing Compounds from Clinacanthus nutans
by: Hazrulrizawati, Hamid, et al.
Published: (2016)

Cytotoxicity of Clinacanthus Nutans Extracts on Human Hepatoma (HepG2) Cell Line
by: Hazrulrizawati, Hamid, et al.
Published: (2016)

Discrimination of Clinacanthus nutans extracts and correlation with antiplasmodial activity using ATR-FTIR fingerprinting
by: Noor Hashim, Noor Haslinda, et al.
Published: (2019)

Semi-purified fraction of Clinacanthus nutans induced apoptosis in human cervical cancer, SiHa cells via up-regulation of bax and down-regulation of Bcl-2
by: Nik Aina Syazana Nik Zainuddin,, et al.
Published: (2019)

Mexico - State-level Public Expenditure Review : The Case of Veracruz-Llave
by: World Bank
Published: (2013)

Assessment of cytotoxicity potency of paclitaxel in combination with Clinacanthus Nutans extracts on human MDA-MB-231 breast cancer cells
by: Nur Hasnieza Mohd Rosli,, et al.
Published: (2018)

Synthesis of silver nanoparticles by clinacanthus nutans extract supported with identification of flavonoids by UPLC-QTOF/MS and its antimicrobial activity
by: Hazrulrizawati, Hamid, et al.
Published: (2019)

Cytotoxicity of Clinacanthus nutans and mechanism of action of its active fraction towards human cervical cancer cell line, HeLA
by: Siti Nur Fatihah Mohd Roslan,, et al.
Published: (2018)

Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction
by: Alam, Md. Ariful, et al.
Published: (2017)

Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics
by: Noor Hashim, Noor Haslinda, et al.
Published: (2016)

Molecular docking
by: Abduallah Alsafi, Hassen Mohammed, et al.
Published: (2011)

Antioxidant and α‐glucosidase inhibitory activities and gas chromatography–mass spectrometry pro le of salak (salacca zalacca) fruit peel extracts
by: Saleh, Mohammed S M, et al.
Published: (2018)

Identification of antioxidants in Momordica charantia fruit using GC-MS metabolomics approach
by: Perumal, Vikneswari, et al.
Published: (2016)

Investigation of α‐glucosidase inhibitory metabolites from Tetracera scandens leaves by GC–MS metabolite profiling and docking studies
by: Ahmed, Nokhala, et al.
Published: (2020)

Hemangioblastoma in the setting of Von Hippel Lindau disease: a case report
by: Raajini Devi K.,, et al.
Published: (2016)

Multivariate calibration of fourier transform infrared spectra in predicting anti-diabetic activity of momordica charantia fruit
by: Perumal, Vikneswari, et al.
Published: (2014)

Molecular docking analysis of β-1,4-Glucosidase from trichoderma harzianum against mycelial cell wall components of macrophomina phaseolina
by: Mohammad Hood, Mohammad Hakim, et al.
Published: (2019)

Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway
by: Zakaria, Zainul Amiruddin, et al.
Published: (2019)

Renal cell carcinoma in a von Hippel-Lindau syndrome; when should pheochromocytoma be anticipated?
by: Mohd Shah, Azarisman Shah, et al.
Published: (2007)

Management of Renal Cell Carcinoma in Von Hippel-Lindau Syndrome: Case Report and Review of Literature
by: Aroona S.,, et al.
Published: (2015)

Screening of various parts of phaleria macrocarpa plant for α-glucosidase inhibitory activity
by: Evan Prince, Sabina, et al.
Published: (2016)

Cannot write session to /tmp/vufind_sessions/sess_f8fln7umq44mr6h1vsss9nebpq