Controlled release electrochemical synthesis and cytotoxicity study of copper(II) nanoparticles in copper(II) decanoate complex

In the present study, a controlled release electrochemical (CRE) technique based on the controlled release of Cu2+ ion from Cu anode in the presence of decanoic acid (HDe) has been used to synthesize Cu(II) decanoate (CuDe2) complex. The effect of applied voltages (1–10V) and electrolyte concentrati...

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Main Authors:	M.Nordin, Norazzizi Atiqah, Samad, Wan Zurina, Kardia, Egi, Yahaya, Badrul Hisham, Yusop, M. R., Othman, Mohamed Rozali
Format:	Article
Language:	English English
Published:	World Scientific Publishing Co. Pte Ltd 2018
Subjects:	QC Physics QD Chemistry QP Physiology
Online Access:	http://irep.iium.edu.my/65505/ http://irep.iium.edu.my/65505/ http://irep.iium.edu.my/65505/ http://irep.iium.edu.my/65505/13/65505_Controlled%20Release%20Electrochemical%20Synthesis_article.pdf http://irep.iium.edu.my/65505/2/65505_Controlled%20Release%20Electrochemical%20Synthesis_scopus.pdf

id	iium-65505
recordtype	eprints
spelling	iium-655052018-08-09T02:22:02Z http://irep.iium.edu.my/65505/ Controlled release electrochemical synthesis and cytotoxicity study of copper(II) nanoparticles in copper(II) decanoate complex M.Nordin, Norazzizi Atiqah Samad, Wan Zurina Kardia, Egi Yahaya, Badrul Hisham Yusop, M. R. Othman, Mohamed Rozali QC Physics QD Chemistry QP Physiology In the present study, a controlled release electrochemical (CRE) technique based on the controlled release of Cu2+ ion from Cu anode in the presence of decanoic acid (HDe) has been used to synthesize Cu(II) decanoate (CuDe2) complex. The effect of applied voltages (1–10V) and electrolyte concentrations (0.1–2.0M CH3COONH4) during the electrolysis on the nanoparticles obtained was studied using TEM. The results reveal that small-sized nanoparticles (2±1nm) were obtained by using lowest applied voltage and CH3COONH4 concentration (1V and 0.1M, respectively). The smallest nanoparticle obtained was then used in the cytotoxicity study against A549 and HeLa cells. The synthesized complex gives moderate cytotoxic effect on the selected cells (IC50=15.85μM and 20.89μM, respectively) and low cytotoxic effect on normal cells (IMR90). Apoptosis is the mode of cell death based on the apoptosis assay that has been conducted. World Scientific Publishing Co. Pte Ltd 2018-05-01 Article NonPeerReviewed application/pdf en http://irep.iium.edu.my/65505/13/65505_Controlled%20Release%20Electrochemical%20Synthesis_article.pdf application/pdf en http://irep.iium.edu.my/65505/2/65505_Controlled%20Release%20Electrochemical%20Synthesis_scopus.pdf M.Nordin, Norazzizi Atiqah and Samad, Wan Zurina and Kardia, Egi and Yahaya, Badrul Hisham and Yusop, M. R. and Othman, Mohamed Rozali (2018) Controlled release electrochemical synthesis and cytotoxicity study of copper(II) nanoparticles in copper(II) decanoate complex. Nano, 13 (5). 1850048-1-1850048-14. ISSN 1793-2920 https://www.worldscientific.com/doi/pdf/10.1142/S1793292018500480 10.1142/S1793292018500480
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	QC Physics QD Chemistry QP Physiology
spellingShingle	QC Physics QD Chemistry QP Physiology M.Nordin, Norazzizi Atiqah Samad, Wan Zurina Kardia, Egi Yahaya, Badrul Hisham Yusop, M. R. Othman, Mohamed Rozali Controlled release electrochemical synthesis and cytotoxicity study of copper(II) nanoparticles in copper(II) decanoate complex
description	In the present study, a controlled release electrochemical (CRE) technique based on the controlled release of Cu2+ ion from Cu anode in the presence of decanoic acid (HDe) has been used to synthesize Cu(II) decanoate (CuDe2) complex. The effect of applied voltages (1–10V) and electrolyte concentrations (0.1–2.0M CH3COONH4) during the electrolysis on the nanoparticles obtained was studied using TEM. The results reveal that small-sized nanoparticles (2±1nm) were obtained by using lowest applied voltage and CH3COONH4 concentration (1V and 0.1M, respectively). The smallest nanoparticle obtained was then used in the cytotoxicity study against A549 and HeLa cells. The synthesized complex gives moderate cytotoxic effect on the selected cells (IC50=15.85μM and 20.89μM, respectively) and low cytotoxic effect on normal cells (IMR90). Apoptosis is the mode of cell death based on the apoptosis assay that has been conducted.
format	Article
author	M.Nordin, Norazzizi Atiqah Samad, Wan Zurina Kardia, Egi Yahaya, Badrul Hisham Yusop, M. R. Othman, Mohamed Rozali
author_facet	M.Nordin, Norazzizi Atiqah Samad, Wan Zurina Kardia, Egi Yahaya, Badrul Hisham Yusop, M. R. Othman, Mohamed Rozali
author_sort	M.Nordin, Norazzizi Atiqah
title	Controlled release electrochemical synthesis and cytotoxicity study of copper(II) nanoparticles in copper(II) decanoate complex
title_short	Controlled release electrochemical synthesis and cytotoxicity study of copper(II) nanoparticles in copper(II) decanoate complex
title_full	Controlled release electrochemical synthesis and cytotoxicity study of copper(II) nanoparticles in copper(II) decanoate complex
title_fullStr	Controlled release electrochemical synthesis and cytotoxicity study of copper(II) nanoparticles in copper(II) decanoate complex
title_full_unstemmed	Controlled release electrochemical synthesis and cytotoxicity study of copper(II) nanoparticles in copper(II) decanoate complex
title_sort	controlled release electrochemical synthesis and cytotoxicity study of copper(ii) nanoparticles in copper(ii) decanoate complex
publisher	World Scientific Publishing Co. Pte Ltd
publishDate	2018
url	http://irep.iium.edu.my/65505/ http://irep.iium.edu.my/65505/ http://irep.iium.edu.my/65505/ http://irep.iium.edu.my/65505/13/65505_Controlled%20Release%20Electrochemical%20Synthesis_article.pdf http://irep.iium.edu.my/65505/2/65505_Controlled%20Release%20Electrochemical%20Synthesis_scopus.pdf
first_indexed	2023-09-18T21:32:56Z
last_indexed	2023-09-18T21:32:56Z
_version_	1777412631746838528

Controlled release electrochemical synthesis and cytotoxicity study of copper(II) nanoparticles in copper(II) decanoate complex

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