Antioxidant activities of Melastoma malabathricum Linn. leaves

Melastoma malabathricum L. (M. malabathricum L.) is a traditional herb that is included in the family of Melastomataceae, it being so attractive with dark – purple magenta flowers and fruits like berries. It possessed many potential pharmacological activities such as anti-inflammatory, anti-bacteri...

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Main Authors:	Abdullah, Adnin, Mat So'ad, Siti Zaiton
Format:	Conference or Workshop Item
Language:	English English
Published:	2018
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/64648/ http://irep.iium.edu.my/64648/ http://irep.iium.edu.my/64648/1/NPRC%20POSTER.pdf http://irep.iium.edu.my/64648/10/64648_Antioxidant%20activities%20of%20Melastoma-abstract%20book.pdf

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recordtype	eprints
spelling	iium-646482018-07-25T00:59:44Z http://irep.iium.edu.my/64648/ Antioxidant activities of Melastoma malabathricum Linn. leaves Abdullah, Adnin Mat So'ad, Siti Zaiton QD Chemistry Melastoma malabathricum L. (M. malabathricum L.) is a traditional herb that is included in the family of Melastomataceae, it being so attractive with dark – purple magenta flowers and fruits like berries. It possessed many potential pharmacological activities such as anti-inflammatory, anti-bacterial, anti-oxidant and gastroprotective activity. This study were aimed to extract M. malabathricum L. leaves using ethyl acetate and methanol. Then, it was to determine the antioxidant activities of M. malabathricum L. and last objective was to separate compounds from M. malabathricum L. leaves extracts using Thin Layer Chromatography (TLC). Extraction were done with two different solvents which were ethyl acetate and methanol. Then the anti-oxidant activity for both ethyl acetate and methanol extract were tested using DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The IC50 calculated were compared with ascorbic acid as control. Then, for TLC test, there were 3 solvent systems used which were 90% chloroform and 10% methanol, 80% chloroform and 20% methanol and 95% ethyl acetate and 5% methanol. Results illustrated that, ethyl acetate extract showed higher anti-oxidant activity compared to methanol extract in which the IC50 were 8.61 µg/mL and 27.37 µg/mL respectively. The IC50 for control was 3.02 µg/mL. Next, for TLC, the solvent system with 90% chloroform and 10% methanol was the best among all the systems. This plant had a big potential as anti-oxidant in future. Then, there were few compounds with different polarity spotted which indicated that variety of compounds that ranged from highest to lowest polarity available in the extracts. 2018-02-23 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/64648/1/NPRC%20POSTER.pdf application/pdf en http://irep.iium.edu.my/64648/10/64648_Antioxidant%20activities%20of%20Melastoma-abstract%20book.pdf Abdullah, Adnin and Mat So'ad, Siti Zaiton (2018) Antioxidant activities of Melastoma malabathricum Linn. leaves. In: 1st MyPSA National Pharmacy Research Competition (NPRC) 2018, 23rd-25th Feb. 2018, Faculty of Pharmacy and Health Sciences, UniKLRCMP. (Unpublished) http://www.rcmp.unikl.edu.my/index.php/17-news-events/94-mypsa-national-pharmacy-research-competition
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	QD Chemistry
spellingShingle	QD Chemistry Abdullah, Adnin Mat So'ad, Siti Zaiton Antioxidant activities of Melastoma malabathricum Linn. leaves
description	Melastoma malabathricum L. (M. malabathricum L.) is a traditional herb that is included in the family of Melastomataceae, it being so attractive with dark – purple magenta flowers and fruits like berries. It possessed many potential pharmacological activities such as anti-inflammatory, anti-bacterial, anti-oxidant and gastroprotective activity. This study were aimed to extract M. malabathricum L. leaves using ethyl acetate and methanol. Then, it was to determine the antioxidant activities of M. malabathricum L. and last objective was to separate compounds from M. malabathricum L. leaves extracts using Thin Layer Chromatography (TLC). Extraction were done with two different solvents which were ethyl acetate and methanol. Then the anti-oxidant activity for both ethyl acetate and methanol extract were tested using DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The IC50 calculated were compared with ascorbic acid as control. Then, for TLC test, there were 3 solvent systems used which were 90% chloroform and 10% methanol, 80% chloroform and 20% methanol and 95% ethyl acetate and 5% methanol. Results illustrated that, ethyl acetate extract showed higher anti-oxidant activity compared to methanol extract in which the IC50 were 8.61 µg/mL and 27.37 µg/mL respectively. The IC50 for control was 3.02 µg/mL. Next, for TLC, the solvent system with 90% chloroform and 10% methanol was the best among all the systems. This plant had a big potential as anti-oxidant in future. Then, there were few compounds with different polarity spotted which indicated that variety of compounds that ranged from highest to lowest polarity available in the extracts.
format	Conference or Workshop Item
author	Abdullah, Adnin Mat So'ad, Siti Zaiton
author_facet	Abdullah, Adnin Mat So'ad, Siti Zaiton
author_sort	Abdullah, Adnin
title	Antioxidant activities of Melastoma malabathricum Linn. leaves
title_short	Antioxidant activities of Melastoma malabathricum Linn. leaves
title_full	Antioxidant activities of Melastoma malabathricum Linn. leaves
title_fullStr	Antioxidant activities of Melastoma malabathricum Linn. leaves
title_full_unstemmed	Antioxidant activities of Melastoma malabathricum Linn. leaves
title_sort	antioxidant activities of melastoma malabathricum linn. leaves
publishDate	2018
url	http://irep.iium.edu.my/64648/ http://irep.iium.edu.my/64648/ http://irep.iium.edu.my/64648/1/NPRC%20POSTER.pdf http://irep.iium.edu.my/64648/10/64648_Antioxidant%20activities%20of%20Melastoma-abstract%20book.pdf
first_indexed	2023-09-18T21:31:45Z
last_indexed	2023-09-18T21:31:45Z
_version_	1777412556741148672

Antioxidant activities of Melastoma malabathricum Linn. leaves

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