Feasibility of salvage selective neck dissection after primary irradiation of pharyngeal and laryngeal carcinoma

Introduction: The concept of neck dissection (ND) in the management armamentarium of head and neck squamous cell carcinoma has evolved throughout the years. Nowadays, ND becomes more functional. Methodology: A retrospective study of 865 patients was performed at Netherlands Cancer Institute-Antoni V...

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Main Authors: Mat Lazim, Norhafiza Hanis Izzuddin, Abdullah, Kahairi, Karakullukçu, Barış M., Tan, Ing Bing
Format: Article
Language:English
English
English
Published: Karger 2018
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Online Access:http://irep.iium.edu.my/64535/
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http://irep.iium.edu.my/64535/13/64535_Feasibility%20of%20Salvage%20Selective%20Neck%20Dissection_article_abstract.pdf
http://irep.iium.edu.my/64535/2/64535_Feasibility%20of%20Salvage%20Selective%20Neck%20Dissection_article_scopus.pdf
http://irep.iium.edu.my/64535/19/64535_Feasibility%20of%20salvage%20selective%20neck%20dissection_WoS.pdf
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spelling iium-645352018-10-18T01:52:56Z http://irep.iium.edu.my/64535/ Feasibility of salvage selective neck dissection after primary irradiation of pharyngeal and laryngeal carcinoma Mat Lazim, Norhafiza Hanis Izzuddin Abdullah, Kahairi Karakullukçu, Barış M. Tan, Ing Bing R Medicine (General) RF Otorhinolaryngology Introduction: The concept of neck dissection (ND) in the management armamentarium of head and neck squamous cell carcinoma has evolved throughout the years. Nowadays, ND becomes more functional. Methodology: A retrospective study of 865 patients was performed at Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital to investigate the feasibility of selective ND (SND). All patients with squamous cell carcinoma of the pharynx and larynx who received primary radiation and underwent salvage ND were included in the study. Result: A total of 29 NDs were analyzed. In 17 neck sides, viable metastases were found (58%), whereas in the other 12 specimens there were no viable metastases. In 16 of the 17 necks (94%), the metastases were located either in level II, III, or IV or in a combination of these 3 levels. Level V was involved in only 1 case (6%). Conclusion: It is well justified to perform a salvage SND (levels II, III, and IV) for pharyngeal and laryngeal carcinoma after primary radiation. In carefully selected cases of supraglottic and oropharyngeal carcinoma, a superselective ND also appears as an efficient option. Karger 2018-05-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/64535/13/64535_Feasibility%20of%20Salvage%20Selective%20Neck%20Dissection_article_abstract.pdf application/pdf en http://irep.iium.edu.my/64535/2/64535_Feasibility%20of%20Salvage%20Selective%20Neck%20Dissection_article_scopus.pdf application/pdf en http://irep.iium.edu.my/64535/19/64535_Feasibility%20of%20salvage%20selective%20neck%20dissection_WoS.pdf Mat Lazim, Norhafiza Hanis Izzuddin and Abdullah, Kahairi and Karakullukçu, Barış M. and Tan, Ing Bing (2018) Feasibility of salvage selective neck dissection after primary irradiation of pharyngeal and laryngeal carcinoma. ORL, 80 (1). pp. 10-18. ISSN 0301-1569 E-ISSN 1423-0275 https://www.karger.com/Article/Abstract/486371 10.1159/000486371
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
English
topic R Medicine (General)
RF Otorhinolaryngology
spellingShingle R Medicine (General)
RF Otorhinolaryngology
Mat Lazim, Norhafiza Hanis Izzuddin
Abdullah, Kahairi
Karakullukçu, Barış M.
Tan, Ing Bing
Feasibility of salvage selective neck dissection after primary irradiation of pharyngeal and laryngeal carcinoma
description Introduction: The concept of neck dissection (ND) in the management armamentarium of head and neck squamous cell carcinoma has evolved throughout the years. Nowadays, ND becomes more functional. Methodology: A retrospective study of 865 patients was performed at Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital to investigate the feasibility of selective ND (SND). All patients with squamous cell carcinoma of the pharynx and larynx who received primary radiation and underwent salvage ND were included in the study. Result: A total of 29 NDs were analyzed. In 17 neck sides, viable metastases were found (58%), whereas in the other 12 specimens there were no viable metastases. In 16 of the 17 necks (94%), the metastases were located either in level II, III, or IV or in a combination of these 3 levels. Level V was involved in only 1 case (6%). Conclusion: It is well justified to perform a salvage SND (levels II, III, and IV) for pharyngeal and laryngeal carcinoma after primary radiation. In carefully selected cases of supraglottic and oropharyngeal carcinoma, a superselective ND also appears as an efficient option.
format Article
author Mat Lazim, Norhafiza Hanis Izzuddin
Abdullah, Kahairi
Karakullukçu, Barış M.
Tan, Ing Bing
author_facet Mat Lazim, Norhafiza Hanis Izzuddin
Abdullah, Kahairi
Karakullukçu, Barış M.
Tan, Ing Bing
author_sort Mat Lazim, Norhafiza Hanis Izzuddin
title Feasibility of salvage selective neck dissection after primary irradiation of pharyngeal and laryngeal carcinoma
title_short Feasibility of salvage selective neck dissection after primary irradiation of pharyngeal and laryngeal carcinoma
title_full Feasibility of salvage selective neck dissection after primary irradiation of pharyngeal and laryngeal carcinoma
title_fullStr Feasibility of salvage selective neck dissection after primary irradiation of pharyngeal and laryngeal carcinoma
title_full_unstemmed Feasibility of salvage selective neck dissection after primary irradiation of pharyngeal and laryngeal carcinoma
title_sort feasibility of salvage selective neck dissection after primary irradiation of pharyngeal and laryngeal carcinoma
publisher Karger
publishDate 2018
url http://irep.iium.edu.my/64535/
http://irep.iium.edu.my/64535/
http://irep.iium.edu.my/64535/
http://irep.iium.edu.my/64535/13/64535_Feasibility%20of%20Salvage%20Selective%20Neck%20Dissection_article_abstract.pdf
http://irep.iium.edu.my/64535/2/64535_Feasibility%20of%20Salvage%20Selective%20Neck%20Dissection_article_scopus.pdf
http://irep.iium.edu.my/64535/19/64535_Feasibility%20of%20salvage%20selective%20neck%20dissection_WoS.pdf
first_indexed 2023-09-18T21:31:35Z
last_indexed 2023-09-18T21:31:35Z
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