Primary Hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma

Hodgkin’s lymphoma (HL) with cutaneous manifestation is a rare condition which usually occurred late in the course of the disease. Due to its rare presentation, misdiagnoses are common. We report a 26-year-old Chinese gentleman who presented with painless and large anterior chest wall ulceration. Co...

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Main Authors:	Wan Ali, Wan Ahmad Syahril Rozli, Tumian, Nur Rafeah
Format:	Article
Language:	English
Published:	2018
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/64422/ http://irep.iium.edu.my/64422/ http://irep.iium.edu.my/64422/1/64422_Primary%20Hodgkin%E2%80%99s%20Lymphoma%20With%20Chest.pdf

id	iium-64422
recordtype	eprints
spelling	iium-644222019-01-03T02:52:32Z http://irep.iium.edu.my/64422/ Primary Hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma Wan Ali, Wan Ahmad Syahril Rozli Tumian, Nur Rafeah R Medicine (General) Hodgkin’s lymphoma (HL) with cutaneous manifestation is a rare condition which usually occurred late in the course of the disease. Due to its rare presentation, misdiagnoses are common. We report a 26-year-old Chinese gentleman who presented with painless and large anterior chest wall ulceration. Computed tomography scan showed sternal mass and erosion, with skin and anterior mediastinal extension. The second histopathologic examination (with immunohistochemistry) of the skin biopsy showed HL with mixed cellularity pattern. However, there was a marked dominance of eosinophils in both the peripheral blood and the tissue samples. This was a very unusual presentation of extranodal HL with ulceration and pronounced hypereosinophilia. The diagnosis was only made after the second biopsy because of the rare occurrence. 2018-04-07 Article PeerReviewed application/pdf en http://irep.iium.edu.my/64422/1/64422_Primary%20Hodgkin%E2%80%99s%20Lymphoma%20With%20Chest.pdf Wan Ali, Wan Ahmad Syahril Rozli and Tumian, Nur Rafeah (2018) Primary Hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma. Indian Journal of Case Reports, 14 (2 (Mar-Apr)). pp. 121-123. ISSN 2454-129X E-ISSN 2454-1203 https://atharvapub.net/index.php/IJCR/article/view/816
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Wan Ali, Wan Ahmad Syahril Rozli Tumian, Nur Rafeah Primary Hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma
description	Hodgkin’s lymphoma (HL) with cutaneous manifestation is a rare condition which usually occurred late in the course of the disease. Due to its rare presentation, misdiagnoses are common. We report a 26-year-old Chinese gentleman who presented with painless and large anterior chest wall ulceration. Computed tomography scan showed sternal mass and erosion, with skin and anterior mediastinal extension. The second histopathologic examination (with immunohistochemistry) of the skin biopsy showed HL with mixed cellularity pattern. However, there was a marked dominance of eosinophils in both the peripheral blood and the tissue samples. This was a very unusual presentation of extranodal HL with ulceration and pronounced hypereosinophilia. The diagnosis was only made after the second biopsy because of the rare occurrence.
format	Article
author	Wan Ali, Wan Ahmad Syahril Rozli Tumian, Nur Rafeah
author_facet	Wan Ali, Wan Ahmad Syahril Rozli Tumian, Nur Rafeah
author_sort	Wan Ali, Wan Ahmad Syahril Rozli
title	Primary Hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma
title_short	Primary Hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma
title_full	Primary Hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma
title_fullStr	Primary Hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma
title_full_unstemmed	Primary Hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma
title_sort	primary hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma
publishDate	2018
url	http://irep.iium.edu.my/64422/ http://irep.iium.edu.my/64422/ http://irep.iium.edu.my/64422/1/64422_Primary%20Hodgkin%E2%80%99s%20Lymphoma%20With%20Chest.pdf
first_indexed	2023-09-18T21:31:27Z
last_indexed	2023-09-18T21:31:27Z
_version_	1777412538442448896

Primary Hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma

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