Phytochemicals screening and antioxidant activities of Malaysian Donax grandis extracts

Common Donax (Donax grandis) is in a family of marantaceae and widely distributed in South East Asia region. Phytochemical constituents in different parts of the plant (leaves, fruits, stems and roots) were extracted by soxhlet extractions using hexane,dichloromethane, methanol and water. Methanoli...

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Main Authors: Mohd Daud, Jamaluddin, Mohd Hassan, Husna Hawa, Hashim, Ridzwan, Taher, Muhammad
Format: Article
Language:English
Published: EuroJournals Publishing, Inc. 2011
Subjects:
Online Access:http://irep.iium.edu.my/6379/
http://irep.iium.edu.my/6379/
http://irep.iium.edu.my/6379/1/EJSR_61_4_10_HUSNA.pdf
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spelling iium-63792011-12-05T04:08:44Z http://irep.iium.edu.my/6379/ Phytochemicals screening and antioxidant activities of Malaysian Donax grandis extracts Mohd Daud, Jamaluddin Mohd Hassan, Husna Hawa Hashim, Ridzwan Taher, Muhammad RS Pharmacy and materia medica Common Donax (Donax grandis) is in a family of marantaceae and widely distributed in South East Asia region. Phytochemical constituents in different parts of the plant (leaves, fruits, stems and roots) were extracted by soxhlet extractions using hexane,dichloromethane, methanol and water. Methanolic extract showed the highest yield of crude extracts from all parts of the plant as compared to the other solvents, including water. Screening tests of the crude extracts revealed the presence of phenolic compounds, alkaloids, tannins, phytosterols, cardiac glycosides, terpenoids, steroids, saponins and flavonoids. Proximate analysis of saponins have also been done for all plant parts of D.grandis using the methanolic extract. The results showed that fruits contained the highest amount of saponins (2.39 wt.%). All parts of the plant samples showed highest total phenolic content (0.18 to 0.65 mg GAE/g). These three solvent fractions possessed strong radical scavenging activity from DPPH, in the ranged from 14.86 to 21.85 mg/mL. The results indicate that D. grandis is a potential candidate to be used as an antioxidant and antiproliferative agents. EuroJournals Publishing, Inc. 2011-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/6379/1/EJSR_61_4_10_HUSNA.pdf Mohd Daud, Jamaluddin and Mohd Hassan, Husna Hawa and Hashim, Ridzwan and Taher, Muhammad (2011) Phytochemicals screening and antioxidant activities of Malaysian Donax grandis extracts. European Journal of Scientific Research, 61 (4). pp. 572-577. ISSN 1450-216X, 1450-202X http://www.eurojournals.com/EJSR_61_4_10.pdf
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RS Pharmacy and materia medica
spellingShingle RS Pharmacy and materia medica
Mohd Daud, Jamaluddin
Mohd Hassan, Husna Hawa
Hashim, Ridzwan
Taher, Muhammad
Phytochemicals screening and antioxidant activities of Malaysian Donax grandis extracts
description Common Donax (Donax grandis) is in a family of marantaceae and widely distributed in South East Asia region. Phytochemical constituents in different parts of the plant (leaves, fruits, stems and roots) were extracted by soxhlet extractions using hexane,dichloromethane, methanol and water. Methanolic extract showed the highest yield of crude extracts from all parts of the plant as compared to the other solvents, including water. Screening tests of the crude extracts revealed the presence of phenolic compounds, alkaloids, tannins, phytosterols, cardiac glycosides, terpenoids, steroids, saponins and flavonoids. Proximate analysis of saponins have also been done for all plant parts of D.grandis using the methanolic extract. The results showed that fruits contained the highest amount of saponins (2.39 wt.%). All parts of the plant samples showed highest total phenolic content (0.18 to 0.65 mg GAE/g). These three solvent fractions possessed strong radical scavenging activity from DPPH, in the ranged from 14.86 to 21.85 mg/mL. The results indicate that D. grandis is a potential candidate to be used as an antioxidant and antiproliferative agents.
format Article
author Mohd Daud, Jamaluddin
Mohd Hassan, Husna Hawa
Hashim, Ridzwan
Taher, Muhammad
author_facet Mohd Daud, Jamaluddin
Mohd Hassan, Husna Hawa
Hashim, Ridzwan
Taher, Muhammad
author_sort Mohd Daud, Jamaluddin
title Phytochemicals screening and antioxidant activities of Malaysian Donax grandis extracts
title_short Phytochemicals screening and antioxidant activities of Malaysian Donax grandis extracts
title_full Phytochemicals screening and antioxidant activities of Malaysian Donax grandis extracts
title_fullStr Phytochemicals screening and antioxidant activities of Malaysian Donax grandis extracts
title_full_unstemmed Phytochemicals screening and antioxidant activities of Malaysian Donax grandis extracts
title_sort phytochemicals screening and antioxidant activities of malaysian donax grandis extracts
publisher EuroJournals Publishing, Inc.
publishDate 2011
url http://irep.iium.edu.my/6379/
http://irep.iium.edu.my/6379/
http://irep.iium.edu.my/6379/1/EJSR_61_4_10_HUSNA.pdf
first_indexed 2023-09-18T20:15:18Z
last_indexed 2023-09-18T20:15:18Z
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