The cardiovascular risk factor profiles among end-stage renal failure patients treated with continuous ambulatory peritoneal dialysis and intermittent hemodialysis
Cardiovascular (CV) event is the most common cause of death in dialysis patients. Both traditional and nontraditional CV risk factors related to malnutrition, inflammation, and anemia are commonly found in this population. This study was conducted to evaluate the burden factors of CV risk factors...
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| Language: | English English |
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The Saudi Center for Organ Transplantation, Riyadh, Kingdom of Saudi Arabia
2018
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| Online Access: | http://irep.iium.edu.my/63356/ http://irep.iium.edu.my/63356/ http://irep.iium.edu.my/63356/ http://irep.iium.edu.my/63356/1/63356_The%20cardiovascular%20risk%20factor%20profiles.pdf http://irep.iium.edu.my/63356/2/63356_The%20cardiovascular%20risk%20factor%20profiles_WOS.pdf |
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iium-633562018-04-26T04:02:08Z http://irep.iium.edu.my/63356/ The cardiovascular risk factor profiles among end-stage renal failure patients treated with continuous ambulatory peritoneal dialysis and intermittent hemodialysis Syed Abdul Kadir, Sharifah Zamiah Draman, Che Rosle Seman, Mohd Ramli Safhan, A. Fariz Abd Razak, Rozalina Nik Idris, Nik Ruzni RA644.3 Public Health. Hygiene. Preventive Medicine - Chronic and Noninfectious Diseases and Public Health Cardiovascular (CV) event is the most common cause of death in dialysis patients. Both traditional and nontraditional CV risk factors related to malnutrition, inflammation, and anemia are commonly found in this population. This study was conducted to evaluate the burden factors of CV risk factors and its management in our regularly dialyzed patients. It was a single- center, cross-sectional analysis of prevalent intermittent hemodialysis (IHD) and continuous ambulatory peritoneal dialysis (CAPD) patients followed up in our hospital. Both the traditional and non-traditional CV risk factors were recorded and compared between the two groups. Eighty-eight patients were recruited. Forty-five were treated with CAPD and 43 patients were treated with IHD. The mean age was 49.5 ± 15.17 years old and 54.5% were females. Eighty percent were Malay followed by Chinese (14.7%) and Indian (5.7%). Thirty-eight percent were hypertensive and 17% were diabetic. The mean age of CAPD patients was 48.9 16.9 compared to 50 13.5 years old for IHD patients (P > 0.05). The body mass index (BMI) of CAPD patients was 23.9 kg/m2 versus 21.7 kg/m2 of the IHD (P = 0.04). The systolic and diastolic blood pressure of CAPD patients were 158 and 89 mm Hg in comparison to 141 and 72 mm Hg in IHD patients (P <0.001) and their total and low-density lipoprotein cholesterol level were 5.93 mmol/L and 3.84 mmol/L versus 4.79 mmol/L and 2.52 mmol/L, respectively (P ≤0.001). The CAPD patients were hyperglycemic more than IHD patients, although it was not statistically significant. All the nontraditional CV risk factors except serum albumin were comparable between the two groups. Serum albumin in CAPD patients was 35.5 g/L compared to 40.8 g/L in the IHD patients (P <0.001). In our prevalent dialysis-dependent patients, bothtraditional and non-traditional CV risk factors are common. Due to the prolonged and continuous glucose exposure from the peritoneal dialysis fluid, the CAPD patients had highly atherogenic serum, higher BMI, and intensified inflammation which pre-disposed them to higher CV events. The Saudi Center for Organ Transplantation, Riyadh, Kingdom of Saudi Arabia 2018-02 Article PeerReviewed application/pdf en http://irep.iium.edu.my/63356/1/63356_The%20cardiovascular%20risk%20factor%20profiles.pdf application/pdf en http://irep.iium.edu.my/63356/2/63356_The%20cardiovascular%20risk%20factor%20profiles_WOS.pdf Syed Abdul Kadir, Sharifah Zamiah and Draman, Che Rosle and Seman, Mohd Ramli and Safhan, A. Fariz and Abd Razak, Rozalina and Nik Idris, Nik Ruzni (2018) The cardiovascular risk factor profiles among end-stage renal failure patients treated with continuous ambulatory peritoneal dialysis and intermittent hemodialysis. Saudi Journal of Kidney Diseases and Transplantation, 29 (1). pp. 114-119. ISSN 1319-2442 E-ISSN 2320-3838 http://www.sjkdt.org/aboutus.asp 10.4103/1319-2442.225185 |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English English |
| topic |
RA644.3 Public Health. Hygiene. Preventive Medicine - Chronic and Noninfectious Diseases and Public Health |
| spellingShingle |
RA644.3 Public Health. Hygiene. Preventive Medicine - Chronic and Noninfectious Diseases and Public Health Syed Abdul Kadir, Sharifah Zamiah Draman, Che Rosle Seman, Mohd Ramli Safhan, A. Fariz Abd Razak, Rozalina Nik Idris, Nik Ruzni The cardiovascular risk factor profiles among end-stage renal failure patients treated with continuous ambulatory peritoneal dialysis and intermittent hemodialysis |
| description |
Cardiovascular (CV) event is the most common cause of death in dialysis patients.
Both traditional and nontraditional CV risk factors related to malnutrition, inflammation, and
anemia are commonly found in this population. This study was conducted to evaluate the burden
factors of CV risk factors and its management in our regularly dialyzed patients. It was a single- center, cross-sectional analysis of prevalent intermittent hemodialysis (IHD) and continuous ambulatory peritoneal dialysis (CAPD) patients followed up in our hospital. Both the traditional and
non-traditional CV risk factors were recorded and compared between the two groups. Eighty-eight patients were recruited. Forty-five were treated with CAPD and 43 patients were treated with IHD.
The mean age was 49.5 ± 15.17 years old and 54.5% were females. Eighty percent were Malay
followed by Chinese (14.7%) and Indian (5.7%). Thirty-eight percent were hypertensive and 17%
were diabetic. The mean age of CAPD patients was 48.9 16.9 compared to 50 13.5 years old for
IHD patients (P > 0.05). The body mass index (BMI) of CAPD patients was 23.9 kg/m2 versus 21.7 kg/m2 of the IHD (P = 0.04). The systolic and diastolic blood pressure of CAPD patients were 158 and 89 mm Hg in comparison to 141 and 72 mm Hg in IHD patients (P <0.001) and their total and low-density lipoprotein cholesterol level were 5.93 mmol/L and 3.84 mmol/L versus 4.79 mmol/L and 2.52 mmol/L, respectively (P ≤0.001). The CAPD patients were hyperglycemic more than IHD patients, although it was not statistically significant. All the nontraditional CV risk factors except serum albumin were comparable between the two groups. Serum albumin in CAPD patients was 35.5 g/L compared to 40.8 g/L in the IHD patients (P <0.001). In our prevalent dialysis-dependent patients, bothtraditional and non-traditional CV risk factors
are common. Due to the prolonged and continuous glucose exposure from the peritoneal dialysis fluid, the CAPD patients had highly atherogenic serum, higher BMI, and intensified inflammation which pre-disposed them to higher CV events. |
| format |
Article |
| author |
Syed Abdul Kadir, Sharifah Zamiah Draman, Che Rosle Seman, Mohd Ramli Safhan, A. Fariz Abd Razak, Rozalina Nik Idris, Nik Ruzni |
| author_facet |
Syed Abdul Kadir, Sharifah Zamiah Draman, Che Rosle Seman, Mohd Ramli Safhan, A. Fariz Abd Razak, Rozalina Nik Idris, Nik Ruzni |
| author_sort |
Syed Abdul Kadir, Sharifah Zamiah |
| title |
The cardiovascular risk factor profiles among end-stage renal failure patients treated with continuous ambulatory peritoneal dialysis and intermittent hemodialysis |
| title_short |
The cardiovascular risk factor profiles among end-stage renal failure patients treated with continuous ambulatory peritoneal dialysis and intermittent hemodialysis |
| title_full |
The cardiovascular risk factor profiles among end-stage renal failure patients treated with continuous ambulatory peritoneal dialysis and intermittent hemodialysis |
| title_fullStr |
The cardiovascular risk factor profiles among end-stage renal failure patients treated with continuous ambulatory peritoneal dialysis and intermittent hemodialysis |
| title_full_unstemmed |
The cardiovascular risk factor profiles among end-stage renal failure patients treated with continuous ambulatory peritoneal dialysis and intermittent hemodialysis |
| title_sort |
cardiovascular risk factor profiles among end-stage renal failure patients treated with continuous ambulatory peritoneal dialysis and intermittent hemodialysis |
| publisher |
The Saudi Center for Organ Transplantation, Riyadh, Kingdom of Saudi Arabia |
| publishDate |
2018 |
| url |
http://irep.iium.edu.my/63356/ http://irep.iium.edu.my/63356/ http://irep.iium.edu.my/63356/ http://irep.iium.edu.my/63356/1/63356_The%20cardiovascular%20risk%20factor%20profiles.pdf http://irep.iium.edu.my/63356/2/63356_The%20cardiovascular%20risk%20factor%20profiles_WOS.pdf |
| first_indexed |
2023-09-18T21:29:52Z |
| last_indexed |
2023-09-18T21:29:52Z |
| _version_ |
1777412438447095808 |