Persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain

Persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain

Persistence Patterns Of Opioid Use Over Three Follow-Up Years: The Difference Between Non-cancer And Cancer Pain Asween Rowena Sani1, Che Suraya Zin1, Abdul Hadi Mohamed1, Munira Izat2, Tan Hung Ling2 and Ng Kim Swan3 1International Islamic University Malaysia, Kuantan, Pahang, Malaysia. 2Hos...

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Main Authors: Abdullah Sani, Asween Rowena, Zin, Che Suraya, Mohamed, Abdul Hadi, Izat, Munira, Ng, Kim Swan
Format: Conference or Workshop Item
Language:English
Published: 2018
Subjects:
RS Pharmacy and materia medica
Online Access:http://irep.iium.edu.my/63286/
http://irep.iium.edu.my/63286/
http://irep.iium.edu.my/63286/1/180404_program_book_abtract_MASP.pdf
id iium-63286
recordtype eprints
spelling iium-632862018-06-26T07:35:58Z http://irep.iium.edu.my/63286/ Persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain Abdullah Sani, Asween Rowena Zin, Che Suraya Mohamed, Abdul Hadi Izat, Munira Ng, Kim Swan RS Pharmacy and materia medica Persistence Patterns Of Opioid Use Over Three Follow-Up Years: The Difference Between Non-cancer And Cancer Pain Asween Rowena Sani1, Che Suraya Zin1, Abdul Hadi Mohamed1, Munira Izat2, Tan Hung Ling2 and Ng Kim Swan3 1International Islamic University Malaysia, Kuantan, Pahang, Malaysia. 2Hospital Kuala Lumpur, Kuala Lumpur, Malaysia. 3Hospital Selayang, Selangor, Malaysia. Background: This study examined the persistence patterns of opioid use in patients with non-cancer and cancer pain over three follow-up years. Methods: All prescriptions for opioids (buprenorphine, dihydrocodeine, fentanyl, oxycodone, morphine) issued by the outpatient tertiary hospital settings between 2013 and 2015 were examined. Wide definition of persistence refers to patients prescribed >0.7DDD or >16.7mg morphine equivalents (MME) per day for at least 3 quarters of a year. Intermediate persistence refers to patients prescribed >1 DDD or 12.3 MME per day in a year, and strict persistence refers to patients prescribed >2 DDD or 49.3 MME per day in a year. Patients who did not meet any of the definitions were categorized as non-persistent. The number of patients in each definition at the end of a 3-year follow-up period were calculated. Analyses were performed using Stata 13. Results: Non-persistent opioid users were predominant in both non-cancer (86%) and cancer (94%) groups. Persistent opioid users in the wide, intermediate, and strict definitions at the end of follow up period were 19% (n=4/21) ,43% (n=3/7), and 25% (n=1/4) vs. 6% (n=2/31), 0% (n=0/3), and 17% (n=1/6) in the non-cancer vs. cancer groups respectively. Conclusion: Non-cancer pain patients in the intermediate and cancer pain in the strict definitions were most likely to continue opioid treatment over a 3-year period. Future work to determine factors related to differential in persistence patterns of opioid use particularly in non-cancer pain patients. Acknowledgement: CSZ was supported by research grants from the Ministry of Education Malaysia Fundamental Research Grant Scheme-FRGS 15-195-0436). 2018-03-19 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/63286/1/180404_program_book_abtract_MASP.pdf Abdullah Sani, Asween Rowena and Zin, Che Suraya and Mohamed, Abdul Hadi and Izat, Munira and Ng, Kim Swan (2018) Persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain. In: 6th Biennial Scientific Meeting Malaysian Association for the Study of Pain 2018, 17th-18th March 2018, Putrajaya, Malaysia. http://www.masp.org.my/
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RS Pharmacy and materia medica
spellingShingle RS Pharmacy and materia medica
Abdullah Sani, Asween Rowena
Zin, Che Suraya
Mohamed, Abdul Hadi
Izat, Munira
Ng, Kim Swan
Persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain
description Persistence Patterns Of Opioid Use Over Three Follow-Up Years: The Difference Between Non-cancer And Cancer Pain Asween Rowena Sani1, Che Suraya Zin1, Abdul Hadi Mohamed1, Munira Izat2, Tan Hung Ling2 and Ng Kim Swan3 1International Islamic University Malaysia, Kuantan, Pahang, Malaysia. 2Hospital Kuala Lumpur, Kuala Lumpur, Malaysia. 3Hospital Selayang, Selangor, Malaysia. Background: This study examined the persistence patterns of opioid use in patients with non-cancer and cancer pain over three follow-up years. Methods: All prescriptions for opioids (buprenorphine, dihydrocodeine, fentanyl, oxycodone, morphine) issued by the outpatient tertiary hospital settings between 2013 and 2015 were examined. Wide definition of persistence refers to patients prescribed >0.7DDD or >16.7mg morphine equivalents (MME) per day for at least 3 quarters of a year. Intermediate persistence refers to patients prescribed >1 DDD or 12.3 MME per day in a year, and strict persistence refers to patients prescribed >2 DDD or 49.3 MME per day in a year. Patients who did not meet any of the definitions were categorized as non-persistent. The number of patients in each definition at the end of a 3-year follow-up period were calculated. Analyses were performed using Stata 13. Results: Non-persistent opioid users were predominant in both non-cancer (86%) and cancer (94%) groups. Persistent opioid users in the wide, intermediate, and strict definitions at the end of follow up period were 19% (n=4/21) ,43% (n=3/7), and 25% (n=1/4) vs. 6% (n=2/31), 0% (n=0/3), and 17% (n=1/6) in the non-cancer vs. cancer groups respectively. Conclusion: Non-cancer pain patients in the intermediate and cancer pain in the strict definitions were most likely to continue opioid treatment over a 3-year period. Future work to determine factors related to differential in persistence patterns of opioid use particularly in non-cancer pain patients. Acknowledgement: CSZ was supported by research grants from the Ministry of Education Malaysia Fundamental Research Grant Scheme-FRGS 15-195-0436).
format Conference or Workshop Item
author Abdullah Sani, Asween Rowena
Zin, Che Suraya
Mohamed, Abdul Hadi
Izat, Munira
Ng, Kim Swan
author_facet Abdullah Sani, Asween Rowena
Zin, Che Suraya
Mohamed, Abdul Hadi
Izat, Munira
Ng, Kim Swan
author_sort Abdullah Sani, Asween Rowena
title Persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain
title_short Persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain
title_full Persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain
title_fullStr Persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain
title_full_unstemmed Persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain
title_sort persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain
publishDate 2018
url http://irep.iium.edu.my/63286/
http://irep.iium.edu.my/63286/
http://irep.iium.edu.my/63286/1/180404_program_book_abtract_MASP.pdf
first_indexed 2023-09-18T21:29:45Z
last_indexed 2023-09-18T21:29:45Z
_version_ 1777412431586263040

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