New quinoxalinone inhibitors targeting secreted phospholipase A2 and alpha-glucosidase
Elevated blood glucose and increased activities of secreted phospholipase A2 (sPLA2) are strongly linked to coronary heart disease. In this report, our goal was to develop small heterocyclic compound that inhibit sPLA2. The title compounds were also tested against α-glucosidase and α-amylase. This a...
Main Authors: | Alasmary, Fatmah A.S., Alnahdi, Fatima S., Ben Bacha, Abir G., El-Araby, Amr M., Moubayed, Nadine Ms, Alafeefy, Ahmed Mahmoud, El-Araby, Moustafa E. |
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Format: | Article |
Language: | English English |
Published: |
Informa Healthcare
2017
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Subjects: | |
Online Access: | http://irep.iium.edu.my/62986/ http://irep.iium.edu.my/62986/ http://irep.iium.edu.my/62986/ http://irep.iium.edu.my/62986/2/62986_New%20quinoxalinone%20inhibitors%20targeting%20secreted_scopus.pdf http://irep.iium.edu.my/62986/13/62986_New%20quinoxalinone%20inhibitors.pdf |
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