Associated factors affecting the successful pregnancy rate of Intrauterine Insemination at International Islamic University Malaysia (IIUM) Fertility Centre
SUMMARY Purpose: The aim was to determine pregnancy rate and its associated factors in Intrauterine Insemination (IUI) at IIUM Fertility Centre. Methods: A retrospective analysis of 504 IUI cycles was conducted on all available records of infertile couples who had undergone IUI treatment at IIU...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Malaysian Medical Association
2011
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/6204/ http://irep.iium.edu.my/6204/ http://irep.iium.edu.my/6204/1/Intrauterine_Insemination_MJM2011.pdf |
| Summary: | SUMMARY
Purpose: The aim was to determine pregnancy rate and its
associated factors in Intrauterine Insemination (IUI) at IIUM
Fertility Centre. Methods: A retrospective analysis of 504 IUI
cycles was conducted on all available records of infertile
couples who had undergone IUI treatment at IIUM Fertility
Centre between 2004 until 2008. The data was collected and
then analyzed with multivariate logistic test with a
significant level of 0.05. Results: The overall clinical
pregnancy rate was 14.5% (73/504). Among 73 pregnancies,
44 cases were live births (60%), 23 cases were miscarriages
(32%) and 6 were ectopic pregnancies (8%). Analysis from
logistic regression revealed two predictive variables which
influence the pregnancy; female age (OR:0.580, CI:0.338-
0.996, p=0.046) and male sperm count (OR:0.506, CI:0.304-
0.843, p=0.008). Pregnancy weren’t related to the etiology of
infertility, duration and type of infertility, cycle number of
IUI, ovarian stimulation protocol and the number of
dominant follicle. Conclusion: IUI remain as a convenient
and useful treatment option in women of younger age (<30
years) and male with higher sperm count (≥100 million per
ml).
KeY WORdS:
IUI, Pregnancy rate, Maternal age, Motile sperm count |
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