Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization

Sonication decellularization treatment requires proper evaluations on its ability to decellularize meniscus tissue efficiently. This study was done to evaluate the histological and biomechanical properties within meniscus scaffolds. Van Gieson staining was done to evaluate the efficiency of cell re...

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Main Authors:	Mohamad Ghazali, Aina Mardhiyah, Sha'ban, Munirah, Noor Azmi, Azran Azhim
Format:	Conference or Workshop Item
Language:	English English
Published:	Institute of Electrical and Electronics Engineers Inc. 2017
Subjects:	TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/61885/ http://irep.iium.edu.my/61885/ http://irep.iium.edu.my/61885/2/61885_Evaluation%20of%20Histological%20and%20Biomechanical%20Properties_SCOPUS.pdf http://irep.iium.edu.my/61885/17/61885_Evaluation%20of%20Histological%20and%20Biomechanical%20Properties.pdf

id	iium-61885
recordtype	eprints
spelling	iium-618852018-06-26T04:24:39Z http://irep.iium.edu.my/61885/ Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization Mohamad Ghazali, Aina Mardhiyah Sha'ban, Munirah Noor Azmi, Azran Azhim TP248.13 Biotechnology Sonication decellularization treatment requires proper evaluations on its ability to decellularize meniscus tissue efficiently. This study was done to evaluate the histological and biomechanical properties within meniscus scaffolds. Van Gieson staining was done to evaluate the efficiency of cell removal in meniscus tissues. The consequences of treatment on viscoelastic properties are vital for scaffolds quality and were properly investigated. Picrosirius red and Safranin-O/Fast green staining was carried out to detect extracellular matrix materials (ECM). Sonication decellularization treatment has the ability to demonstrated complete nuclei removal compare to control samples as well as maintaining viscoelastic properties, namely stiffness, compression and residual force. Thus, sonication decellularization treatment had successfully produced and prepared a meniscus bioscaffold candidate in which its biomechanical strength is sustained through protection of ECM properties. Institute of Electrical and Electronics Engineers Inc. 2017-07 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/61885/2/61885_Evaluation%20of%20Histological%20and%20Biomechanical%20Properties_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/61885/17/61885_Evaluation%20of%20Histological%20and%20Biomechanical%20Properties.pdf Mohamad Ghazali, Aina Mardhiyah and Sha'ban, Munirah and Noor Azmi, Azran Azhim (2017) Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization. In: 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 201), 11th-15th July 2017, Jeju Island; South Korea. http://ieeexplore.ieee.org/document/8037259/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	TP248.13 Biotechnology
spellingShingle	TP248.13 Biotechnology Mohamad Ghazali, Aina Mardhiyah Sha'ban, Munirah Noor Azmi, Azran Azhim Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization
description	Sonication decellularization treatment requires proper evaluations on its ability to decellularize meniscus tissue efficiently. This study was done to evaluate the histological and biomechanical properties within meniscus scaffolds. Van Gieson staining was done to evaluate the efficiency of cell removal in meniscus tissues. The consequences of treatment on viscoelastic properties are vital for scaffolds quality and were properly investigated. Picrosirius red and Safranin-O/Fast green staining was carried out to detect extracellular matrix materials (ECM). Sonication decellularization treatment has the ability to demonstrated complete nuclei removal compare to control samples as well as maintaining viscoelastic properties, namely stiffness, compression and residual force. Thus, sonication decellularization treatment had successfully produced and prepared a meniscus bioscaffold candidate in which its biomechanical strength is sustained through protection of ECM properties.
format	Conference or Workshop Item
author	Mohamad Ghazali, Aina Mardhiyah Sha'ban, Munirah Noor Azmi, Azran Azhim
author_facet	Mohamad Ghazali, Aina Mardhiyah Sha'ban, Munirah Noor Azmi, Azran Azhim
author_sort	Mohamad Ghazali, Aina Mardhiyah
title	Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization
title_short	Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization
title_full	Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization
title_fullStr	Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization
title_full_unstemmed	Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization
title_sort	evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization
publisher	Institute of Electrical and Electronics Engineers Inc.
publishDate	2017
url	http://irep.iium.edu.my/61885/ http://irep.iium.edu.my/61885/ http://irep.iium.edu.my/61885/2/61885_Evaluation%20of%20Histological%20and%20Biomechanical%20Properties_SCOPUS.pdf http://irep.iium.edu.my/61885/17/61885_Evaluation%20of%20Histological%20and%20Biomechanical%20Properties.pdf
first_indexed	2023-09-18T21:27:48Z
last_indexed	2023-09-18T21:27:48Z
_version_	1777412308350271488

Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization

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