Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa

his study was designed to evaluate the antibacterial activity of Thymus capitatus and two of its major components namely thymol and carvacrol. The dried leaves were extracted using soxhlet apparatus. Thymol and carvacrol were isolated using normal phase column chromatography. The antibacterial activ...

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Main Authors:	Althunibat, Osama Yousef, Qaralleh, Haitham, Abboud, Muayad, Khleifat, Khaled, Majali, Ibrahim S., Darnis, Deny Susanti, Aldal'In, Hammad Khalifeh H., Yassin Ahmed Al-dalin, Sati
Format:	Article
Language:	English English
Published:	Journal of Pure and Applied Microbiology 2016
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/61528/ http://irep.iium.edu.my/61528/ http://irep.iium.edu.my/61528/7/61528_Effect%20of%20Thymol%20and%20Carvacrol_article.pdf http://irep.iium.edu.my/61528/13/61528_Effect%20of%20Thymol%20and%20Carvacrol_scopus.pdf

id	iium-61528
recordtype	eprints
spelling	iium-615282018-07-11T00:28:07Z http://irep.iium.edu.my/61528/ Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa Althunibat, Osama Yousef Qaralleh, Haitham Abboud, Muayad Khleifat, Khaled Majali, Ibrahim S. Darnis, Deny Susanti Aldal'In, Hammad Khalifeh H. Yassin Ahmed Al-dalin, Sati QD Chemistry his study was designed to evaluate the antibacterial activity of Thymus capitatus and two of its major components namely thymol and carvacrol. The dried leaves were extracted using soxhlet apparatus. Thymol and carvacrol were isolated using normal phase column chromatography. The antibacterial activity of the leaves extract, thymol and carvacrol were estimated using agar disc diffusion and broth dilution methods against four bacterial strains. The leaves extract was found to show a broad spectrum of antibacterial activity against all the tested bacterial strains. Pseudomonas aeruginosa was the most sensitive bacteria. The purified compounds exhibited relatively stronger antibacterial activity than the extract. Thymol fraction exhibited stronger antibacterial activity than carvacrol. Thymol fraction exhibited MIC values ranging from 0.005 – 0.008 mg/mL while carvacrol fraction exhibited MIC values ranging from 0.007 – 0.008 mg/mL. Journal of Pure and Applied Microbiology 2016-03 Article NonPeerReviewed application/pdf en http://irep.iium.edu.my/61528/7/61528_Effect%20of%20Thymol%20and%20Carvacrol_article.pdf application/pdf en http://irep.iium.edu.my/61528/13/61528_Effect%20of%20Thymol%20and%20Carvacrol_scopus.pdf Althunibat, Osama Yousef and Qaralleh, Haitham and Abboud, Muayad and Khleifat, Khaled and Majali, Ibrahim S. and Darnis, Deny Susanti and Aldal'In, Hammad Khalifeh H. and Yassin Ahmed Al-dalin, Sati (2016) Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa. Journal of Pure and gyApplied Microbiology, 10 (1). pp. 367-374. ISSN 0973-7510 (In Press) http://microbiologyjournal.org/jmabsarchive.php?vol=10&issue=1
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	QD Chemistry
spellingShingle	QD Chemistry Althunibat, Osama Yousef Qaralleh, Haitham Abboud, Muayad Khleifat, Khaled Majali, Ibrahim S. Darnis, Deny Susanti Aldal'In, Hammad Khalifeh H. Yassin Ahmed Al-dalin, Sati Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa
description	his study was designed to evaluate the antibacterial activity of Thymus capitatus and two of its major components namely thymol and carvacrol. The dried leaves were extracted using soxhlet apparatus. Thymol and carvacrol were isolated using normal phase column chromatography. The antibacterial activity of the leaves extract, thymol and carvacrol were estimated using agar disc diffusion and broth dilution methods against four bacterial strains. The leaves extract was found to show a broad spectrum of antibacterial activity against all the tested bacterial strains. Pseudomonas aeruginosa was the most sensitive bacteria. The purified compounds exhibited relatively stronger antibacterial activity than the extract. Thymol fraction exhibited stronger antibacterial activity than carvacrol. Thymol fraction exhibited MIC values ranging from 0.005 – 0.008 mg/mL while carvacrol fraction exhibited MIC values ranging from 0.007 – 0.008 mg/mL.
format	Article
author	Althunibat, Osama Yousef Qaralleh, Haitham Abboud, Muayad Khleifat, Khaled Majali, Ibrahim S. Darnis, Deny Susanti Aldal'In, Hammad Khalifeh H. Yassin Ahmed Al-dalin, Sati
author_facet	Althunibat, Osama Yousef Qaralleh, Haitham Abboud, Muayad Khleifat, Khaled Majali, Ibrahim S. Darnis, Deny Susanti Aldal'In, Hammad Khalifeh H. Yassin Ahmed Al-dalin, Sati
author_sort	Althunibat, Osama Yousef
title	Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa
title_short	Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa
title_full	Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa
title_fullStr	Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa
title_full_unstemmed	Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa
title_sort	effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa
publisher	Journal of Pure and Applied Microbiology
publishDate	2016
url	http://irep.iium.edu.my/61528/ http://irep.iium.edu.my/61528/ http://irep.iium.edu.my/61528/7/61528_Effect%20of%20Thymol%20and%20Carvacrol_article.pdf http://irep.iium.edu.my/61528/13/61528_Effect%20of%20Thymol%20and%20Carvacrol_scopus.pdf
first_indexed	2023-09-18T21:27:17Z
last_indexed	2023-09-18T21:27:17Z
_version_	1777412276121239552

Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa

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