Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed
Jacalin is a major lectin present in jackfruit seeds, obtained by crude protein recovery. Its lectin symbol is AIL and it belongs to the galactose family of N-acetylglucosamine binding lectins, which are recognized to be cancer cell inhibitor. There have been many pharmacological research studies...
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iium-614692018-01-16T07:16:18Z http://irep.iium.edu.my/61469/ Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed M.A., Zuraidah Akbar John, B. Yunus, Kamaruzzaman Q Science (General) Jacalin is a major lectin present in jackfruit seeds, obtained by crude protein recovery. Its lectin symbol is AIL and it belongs to the galactose family of N-acetylglucosamine binding lectins, which are recognized to be cancer cell inhibitor. There have been many pharmacological research studies focusing intensively on jacalin, however their scope was restricted to the application of jacalin in pharmacology. Jacalin or lectin extract from jackfruit seed were induced cell cycle arrest in human breast cancer cell, MCF7, in comparison of crude extract, purified jacalin and jacalin standard. IC50 for MCF7 was achieved at concentration 125 µg/mL, comparable to jacalin standard with only 1.60 % contradictions. Zibeline International Publishing Sdn. Bhd 2017 Article PeerReviewed application/pdf en http://irep.iium.edu.my/61469/1/73.pdf M.A., Zuraidah and Akbar John, B. and Yunus, Kamaruzzaman (2017) Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed. Science Heritage Journal/Galeri Warisan Sains (GWS), 1 (2). pp. 16-18. ISSN 2521-0858 E-ISSN 2521-0866 https://zibelinepub.com/archives/2gws2017/2gws2017-16-18.pdf 10.26480/gws.02.2017.16.18 |
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Q Science (General) M.A., Zuraidah Akbar John, B. Yunus, Kamaruzzaman Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed |
description |
Jacalin is a major lectin present in jackfruit seeds, obtained by crude protein recovery. Its lectin symbol is AIL and it
belongs to the galactose family of N-acetylglucosamine binding lectins, which are recognized to be cancer cell
inhibitor. There have been many pharmacological research studies focusing intensively on jacalin, however their
scope was restricted to the application of jacalin in pharmacology. Jacalin or lectin extract from jackfruit seed were
induced cell cycle arrest in human breast cancer cell, MCF7, in comparison of crude extract, purified jacalin and jacalin
standard. IC50 for MCF7 was achieved at concentration 125 µg/mL, comparable to jacalin standard with only 1.60 %
contradictions. |
format |
Article |
author |
M.A., Zuraidah Akbar John, B. Yunus, Kamaruzzaman |
author_facet |
M.A., Zuraidah Akbar John, B. Yunus, Kamaruzzaman |
author_sort |
M.A., Zuraidah |
title |
Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed |
title_short |
Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed |
title_full |
Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed |
title_fullStr |
Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed |
title_full_unstemmed |
Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed |
title_sort |
cytotoxicity on mcf7 cell lines exposed to an extract of the jacalin from jackfruit seed |
publisher |
Zibeline International Publishing Sdn. Bhd |
publishDate |
2017 |
url |
http://irep.iium.edu.my/61469/ http://irep.iium.edu.my/61469/ http://irep.iium.edu.my/61469/ http://irep.iium.edu.my/61469/1/73.pdf |
first_indexed |
2023-09-18T21:27:11Z |
last_indexed |
2023-09-18T21:27:11Z |
_version_ |
1777412270261796864 |