Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed

Jacalin is a major lectin present in jackfruit seeds, obtained by crude protein recovery. Its lectin symbol is AIL and it belongs to the galactose family of N-acetylglucosamine binding lectins, which are recognized to be cancer cell inhibitor. There have been many pharmacological research studies...

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Main Authors: M.A., Zuraidah, Akbar John, B., Yunus, Kamaruzzaman
Format: Article
Language:English
Published: Zibeline International Publishing Sdn. Bhd 2017
Subjects:
Online Access:http://irep.iium.edu.my/61469/
http://irep.iium.edu.my/61469/
http://irep.iium.edu.my/61469/
http://irep.iium.edu.my/61469/1/73.pdf
id iium-61469
recordtype eprints
spelling iium-614692018-01-16T07:16:18Z http://irep.iium.edu.my/61469/ Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed M.A., Zuraidah Akbar John, B. Yunus, Kamaruzzaman Q Science (General) Jacalin is a major lectin present in jackfruit seeds, obtained by crude protein recovery. Its lectin symbol is AIL and it belongs to the galactose family of N-acetylglucosamine binding lectins, which are recognized to be cancer cell inhibitor. There have been many pharmacological research studies focusing intensively on jacalin, however their scope was restricted to the application of jacalin in pharmacology. Jacalin or lectin extract from jackfruit seed were induced cell cycle arrest in human breast cancer cell, MCF7, in comparison of crude extract, purified jacalin and jacalin standard. IC50 for MCF7 was achieved at concentration 125 µg/mL, comparable to jacalin standard with only 1.60 % contradictions. Zibeline International Publishing Sdn. Bhd 2017 Article PeerReviewed application/pdf en http://irep.iium.edu.my/61469/1/73.pdf M.A., Zuraidah and Akbar John, B. and Yunus, Kamaruzzaman (2017) Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed. Science Heritage Journal/Galeri Warisan Sains (GWS), 1 (2). pp. 16-18. ISSN 2521-0858 E-ISSN 2521-0866 https://zibelinepub.com/archives/2gws2017/2gws2017-16-18.pdf 10.26480/gws.02.2017.16.18
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic Q Science (General)
spellingShingle Q Science (General)
M.A., Zuraidah
Akbar John, B.
Yunus, Kamaruzzaman
Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed
description Jacalin is a major lectin present in jackfruit seeds, obtained by crude protein recovery. Its lectin symbol is AIL and it belongs to the galactose family of N-acetylglucosamine binding lectins, which are recognized to be cancer cell inhibitor. There have been many pharmacological research studies focusing intensively on jacalin, however their scope was restricted to the application of jacalin in pharmacology. Jacalin or lectin extract from jackfruit seed were induced cell cycle arrest in human breast cancer cell, MCF7, in comparison of crude extract, purified jacalin and jacalin standard. IC50 for MCF7 was achieved at concentration 125 µg/mL, comparable to jacalin standard with only 1.60 % contradictions.
format Article
author M.A., Zuraidah
Akbar John, B.
Yunus, Kamaruzzaman
author_facet M.A., Zuraidah
Akbar John, B.
Yunus, Kamaruzzaman
author_sort M.A., Zuraidah
title Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed
title_short Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed
title_full Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed
title_fullStr Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed
title_full_unstemmed Cytotoxicity on MCF7 cell lines exposed to an extract of the jacalin from jackfruit seed
title_sort cytotoxicity on mcf7 cell lines exposed to an extract of the jacalin from jackfruit seed
publisher Zibeline International Publishing Sdn. Bhd
publishDate 2017
url http://irep.iium.edu.my/61469/
http://irep.iium.edu.my/61469/
http://irep.iium.edu.my/61469/
http://irep.iium.edu.my/61469/1/73.pdf
first_indexed 2023-09-18T21:27:11Z
last_indexed 2023-09-18T21:27:11Z
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