Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves

Leaves of Tetracera indica are used in traditional medicine for the treatment of diabetes mellitus in Malaysia. This study was aimed at investigating the phytochemical constituents present in T. indica leaves which may be responsible for the antidiabetic effect of the plant’s leaves. Crude methanoli...

Full description

Bibliographic Details
Main Authors:	Ahmed, Qamar Uddin, Alhassan, MA, Hasan, Md. Mahmudul (Stu), Khatib, Alfi, Sarian, Murni Nazira, Latip, Jalifah
Format:	Conference or Workshop Item
Language:	English
Published:	2016
Subjects:	Q Science (General) QD Chemistry
Online Access:	http://irep.iium.edu.my/61096/ http://irep.iium.edu.my/61096/ http://irep.iium.edu.my/61096/18/61096_Isolation%20and%20identification%20of%20flavonoids_complete.pdf

id	iium-61096
recordtype	eprints
spelling	iium-610962019-01-04T03:06:39Z http://irep.iium.edu.my/61096/ Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves Ahmed, Qamar Uddin Alhassan, MA Hasan, Md. Mahmudul (Stu) Khatib, Alfi Sarian, Murni Nazira Latip, Jalifah Q Science (General) QD Chemistry Leaves of Tetracera indica are used in traditional medicine for the treatment of diabetes mellitus in Malaysia. This study was aimed at investigating the phytochemical constituents present in T. indica leaves which may be responsible for the antidiabetic effect of the plant’s leaves. Crude methanolic extract from the leaves of T. indica was separated and purified by column chromatography of silica gel, ODS and sephadex LH-20. The structures of the isolated compounds were identified and elucidated by UV, 1H-NMR, 13C-NMR and MS spectroscopic techniques. Four flavonoids were isolated from the leaves of T. indica, and these compounds were identified as follows: 5,7-dihydroxy-8-methoxyflavone (wogonin), 5,7,8-trihydroxyflavone (norwogonin), quercetin and 5-Hydroxy-7-methoxyflavone (tectochrysin). The three compounds i.e. norwogonin, quercetin and tectochrysin are being reported for the first time from T. indica leaves. Keywords: Tetracera indica, flavonoids, diabetes mellitus 2016 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/61096/18/61096_Isolation%20and%20identification%20of%20flavonoids_complete.pdf Ahmed, Qamar Uddin and Alhassan, MA and Hasan, Md. Mahmudul (Stu) and Khatib, Alfi and Sarian, Murni Nazira and Latip, Jalifah (2016) Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves. In: 2nd International Conference on Industrial Pharmacy (ICIP 2016), 15th-16th Aug. 2016, Kuantan, Pahang. (Unpublished) http://www.iium.edu.my/icip2016/downloads/programmebook.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	Q Science (General) QD Chemistry
spellingShingle	Q Science (General) QD Chemistry Ahmed, Qamar Uddin Alhassan, MA Hasan, Md. Mahmudul (Stu) Khatib, Alfi Sarian, Murni Nazira Latip, Jalifah Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves
description	Leaves of Tetracera indica are used in traditional medicine for the treatment of diabetes mellitus in Malaysia. This study was aimed at investigating the phytochemical constituents present in T. indica leaves which may be responsible for the antidiabetic effect of the plant’s leaves. Crude methanolic extract from the leaves of T. indica was separated and purified by column chromatography of silica gel, ODS and sephadex LH-20. The structures of the isolated compounds were identified and elucidated by UV, 1H-NMR, 13C-NMR and MS spectroscopic techniques. Four flavonoids were isolated from the leaves of T. indica, and these compounds were identified as follows: 5,7-dihydroxy-8-methoxyflavone (wogonin), 5,7,8-trihydroxyflavone (norwogonin), quercetin and 5-Hydroxy-7-methoxyflavone (tectochrysin). The three compounds i.e. norwogonin, quercetin and tectochrysin are being reported for the first time from T. indica leaves. Keywords: Tetracera indica, flavonoids, diabetes mellitus
format	Conference or Workshop Item
author	Ahmed, Qamar Uddin Alhassan, MA Hasan, Md. Mahmudul (Stu) Khatib, Alfi Sarian, Murni Nazira Latip, Jalifah
author_facet	Ahmed, Qamar Uddin Alhassan, MA Hasan, Md. Mahmudul (Stu) Khatib, Alfi Sarian, Murni Nazira Latip, Jalifah
author_sort	Ahmed, Qamar Uddin
title	Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves
title_short	Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves
title_full	Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves
title_fullStr	Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves
title_full_unstemmed	Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves
title_sort	isolation and identification of flavonoids from tetracera indica merr. (dilleniaceae) leaves
publishDate	2016
url	http://irep.iium.edu.my/61096/ http://irep.iium.edu.my/61096/ http://irep.iium.edu.my/61096/18/61096_Isolation%20and%20identification%20of%20flavonoids_complete.pdf
first_indexed	2023-09-18T21:26:38Z
last_indexed	2023-09-18T21:26:38Z
_version_	1777412235815026688

Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves

Similar Items