Patterns of statin therapy prescribing among hospitalized patients with type 2 diabetes mellitus in two Malaysian tertiary hospitals
Purpose: To assess the patterns of statin therapy prescribing among hospitalized patients with type 2 diabetes mellitus (T2DM) in two Malaysian tertiary healthcare institutions and to determine compliance with Malaysian treatment guidelines. Methods: A cross-sectional study was conducted from Sep...
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| Format: | Article |
| Language: | English English |
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Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 Nigeria.
2017
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| Online Access: | http://irep.iium.edu.my/61034/ http://irep.iium.edu.my/61034/ http://irep.iium.edu.my/61034/ http://irep.iium.edu.my/61034/1/Patterns%20of%20statin%20therapy%20in%20hospitals%20Dec%202017.pdf http://irep.iium.edu.my/61034/7/61034_Patterns%20of%20statin%20therapy%20prescribing%20among%20hospitalized_SCOPUS.pdf |
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eprints |
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iium-610342018-07-10T09:39:26Z http://irep.iium.edu.my/61034/ Patterns of statin therapy prescribing among hospitalized patients with type 2 diabetes mellitus in two Malaysian tertiary hospitals Elnaem, Mohamed Hassan Nik Mohamed, Mohamad Haniki Huri, Hasniza Zaman Mohd Shah, Azarisman Shah RC Internal medicine RM Therapeutics. Pharmacology RM283 Endocrinotheraphy RS Pharmacy and materia medica Purpose: To assess the patterns of statin therapy prescribing among hospitalized patients with type 2 diabetes mellitus (T2DM) in two Malaysian tertiary healthcare institutions and to determine compliance with Malaysian treatment guidelines. Methods: A cross-sectional study was conducted from September to December 2016. The study involved hospitalized T2DM patients aged between 40 to 75 years recruited from the medical wards of two tertiary hospitals in the state of Pahang, Malaysia. Evaluation of statin prescribing was classified as appropriate (statin therapy was prescribed with no concurrent drug interactions) or inappropriate (not receiving any statins, although no contraindications), or potentially inappropriate (drug interactions detected or renal dose adjustment needed). Results: Among the 393 medical records screened, 65 % had a statin therapy prescription. The evaluation of statins prescribing showed that approximately 35 % of patients were not prescribed statins, contrary to national treatment guidelines. Twenty-six percent of the study cases were given drugs that interacted with statins. Renal dose adjustment of the given statin was needed in 5 % of patients. Finally, only one-third of the patients were prescribed appropriate statin doses. Conclusion: A significant portion of T2DM hospitalized patients did not receive their recommended statin therapy for cardiovascular disease prophylaxis. Closer monitoring and further dose adjustments are warranted to optimize statin therapy prescribing. Further interventions to improve statin prescribing should be considered. Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 Nigeria. 2017-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/61034/1/Patterns%20of%20statin%20therapy%20in%20hospitals%20Dec%202017.pdf application/pdf en http://irep.iium.edu.my/61034/7/61034_Patterns%20of%20statin%20therapy%20prescribing%20among%20hospitalized_SCOPUS.pdf Elnaem, Mohamed Hassan and Nik Mohamed, Mohamad Haniki and Huri, Hasniza Zaman and Mohd Shah, Azarisman Shah (2017) Patterns of statin therapy prescribing among hospitalized patients with type 2 diabetes mellitus in two Malaysian tertiary hospitals. Tropical Journal of Pharmaceutical Research, 16 (12). pp. 3005-3011. ISSN 1596-5996 E-ISSN 1596-9827 https://www.tjpr.org/admin/12389900798187/2017_16_12_27.pdf 10.4314/tjpr.v16i12.27 |
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Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English English |
| topic |
RC Internal medicine RM Therapeutics. Pharmacology RM283 Endocrinotheraphy RS Pharmacy and materia medica |
| spellingShingle |
RC Internal medicine RM Therapeutics. Pharmacology RM283 Endocrinotheraphy RS Pharmacy and materia medica Elnaem, Mohamed Hassan Nik Mohamed, Mohamad Haniki Huri, Hasniza Zaman Mohd Shah, Azarisman Shah Patterns of statin therapy prescribing among hospitalized patients with type 2 diabetes mellitus in two Malaysian tertiary hospitals |
| description |
Purpose: To assess the patterns of statin therapy prescribing among hospitalized patients with type 2
diabetes mellitus (T2DM) in two Malaysian tertiary healthcare institutions and to determine compliance
with Malaysian treatment guidelines.
Methods: A cross-sectional study was conducted from September to December 2016. The study
involved hospitalized T2DM patients aged between 40 to 75 years recruited from the medical wards of
two tertiary hospitals in the state of Pahang, Malaysia. Evaluation of statin prescribing was classified as
appropriate (statin therapy was prescribed with no concurrent drug interactions) or inappropriate (not
receiving any statins, although no contraindications), or potentially inappropriate (drug interactions
detected or renal dose adjustment needed).
Results: Among the 393 medical records screened, 65 % had a statin therapy prescription. The
evaluation of statins prescribing showed that approximately 35 % of patients were not prescribed
statins, contrary to national treatment guidelines. Twenty-six percent of the study cases were given
drugs that interacted with statins. Renal dose adjustment of the given statin was needed in 5 % of
patients. Finally, only one-third of the patients were prescribed appropriate statin doses.
Conclusion: A significant portion of T2DM hospitalized patients did not receive their recommended
statin therapy for cardiovascular disease prophylaxis. Closer monitoring and further dose adjustments
are warranted to optimize statin therapy prescribing. Further interventions to improve statin prescribing
should be considered. |
| format |
Article |
| author |
Elnaem, Mohamed Hassan Nik Mohamed, Mohamad Haniki Huri, Hasniza Zaman Mohd Shah, Azarisman Shah |
| author_facet |
Elnaem, Mohamed Hassan Nik Mohamed, Mohamad Haniki Huri, Hasniza Zaman Mohd Shah, Azarisman Shah |
| author_sort |
Elnaem, Mohamed Hassan |
| title |
Patterns of statin therapy prescribing among hospitalized
patients with type 2 diabetes mellitus in two Malaysian
tertiary hospitals |
| title_short |
Patterns of statin therapy prescribing among hospitalized
patients with type 2 diabetes mellitus in two Malaysian
tertiary hospitals |
| title_full |
Patterns of statin therapy prescribing among hospitalized
patients with type 2 diabetes mellitus in two Malaysian
tertiary hospitals |
| title_fullStr |
Patterns of statin therapy prescribing among hospitalized
patients with type 2 diabetes mellitus in two Malaysian
tertiary hospitals |
| title_full_unstemmed |
Patterns of statin therapy prescribing among hospitalized
patients with type 2 diabetes mellitus in two Malaysian
tertiary hospitals |
| title_sort |
patterns of statin therapy prescribing among hospitalized
patients with type 2 diabetes mellitus in two malaysian
tertiary hospitals |
| publisher |
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 Nigeria. |
| publishDate |
2017 |
| url |
http://irep.iium.edu.my/61034/ http://irep.iium.edu.my/61034/ http://irep.iium.edu.my/61034/ http://irep.iium.edu.my/61034/1/Patterns%20of%20statin%20therapy%20in%20hospitals%20Dec%202017.pdf http://irep.iium.edu.my/61034/7/61034_Patterns%20of%20statin%20therapy%20prescribing%20among%20hospitalized_SCOPUS.pdf |
| first_indexed |
2023-09-18T21:26:33Z |
| last_indexed |
2023-09-18T21:26:33Z |
| _version_ |
1777412230334119936 |