Patterns of statin therapy prescribing among hospitalized patients with type 2 diabetes mellitus in two Malaysian tertiary hospitals
Purpose: To assess the patterns of statin therapy prescribing among hospitalized patients with type 2 diabetes mellitus (T2DM) in two Malaysian tertiary healthcare institutions and to determine compliance with Malaysian treatment guidelines. Methods: A cross-sectional study was conducted from Sep...
Main Authors: | , , , |
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Format: | Article |
Language: | English English |
Published: |
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 Nigeria.
2017
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Subjects: | |
Online Access: | http://irep.iium.edu.my/61034/ http://irep.iium.edu.my/61034/ http://irep.iium.edu.my/61034/ http://irep.iium.edu.my/61034/1/Patterns%20of%20statin%20therapy%20in%20hospitals%20Dec%202017.pdf http://irep.iium.edu.my/61034/7/61034_Patterns%20of%20statin%20therapy%20prescribing%20among%20hospitalized_SCOPUS.pdf |
Summary: | Purpose: To assess the patterns of statin therapy prescribing among hospitalized patients with type 2
diabetes mellitus (T2DM) in two Malaysian tertiary healthcare institutions and to determine compliance
with Malaysian treatment guidelines.
Methods: A cross-sectional study was conducted from September to December 2016. The study
involved hospitalized T2DM patients aged between 40 to 75 years recruited from the medical wards of
two tertiary hospitals in the state of Pahang, Malaysia. Evaluation of statin prescribing was classified as
appropriate (statin therapy was prescribed with no concurrent drug interactions) or inappropriate (not
receiving any statins, although no contraindications), or potentially inappropriate (drug interactions
detected or renal dose adjustment needed).
Results: Among the 393 medical records screened, 65 % had a statin therapy prescription. The
evaluation of statins prescribing showed that approximately 35 % of patients were not prescribed
statins, contrary to national treatment guidelines. Twenty-six percent of the study cases were given
drugs that interacted with statins. Renal dose adjustment of the given statin was needed in 5 % of
patients. Finally, only one-third of the patients were prescribed appropriate statin doses.
Conclusion: A significant portion of T2DM hospitalized patients did not receive their recommended
statin therapy for cardiovascular disease prophylaxis. Closer monitoring and further dose adjustments
are warranted to optimize statin therapy prescribing. Further interventions to improve statin prescribing
should be considered. |
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