Appearance of lipid floating and tear film stability in non-dry and dry eye subjects

Introduction: Assessment of lipid component of the tear film is still poorly described. The purpose of the study is to evaluate the appearance of lipid floating and tear film stability in non-dry and dry eye subjects. Methods: All subjects were classified as dry eye and non-dry eye patients by us...

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Bibliographic Details
Main Authors: Ithnin, Mohd. Hafidz, Ariffin, Azrin Esmady, Mohd Kamal, Khairidzan
Format: Article
Language:English
Published: Faculty of Medicine, University of Malaya 2017
Subjects:
Online Access:http://irep.iium.edu.my/61012/
http://irep.iium.edu.my/61012/
http://irep.iium.edu.my/61012/7/61012-APPEARANCE%20OF%20LIPID%20FLOATING.pdf
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Summary:Introduction: Assessment of lipid component of the tear film is still poorly described. The purpose of the study is to evaluate the appearance of lipid floating and tear film stability in non-dry and dry eye subjects. Methods: All subjects were classified as dry eye and non-dry eye patients by using two different criteria; Classification 1 and Classification 2. The lipid floating time (LFT) and TFBUT were evaluated using slit lamp videography. The correlation analysis was conducted between LFT and TFBUT on all subjects. LFT and TFBUT were compared between non-dry and dry eye subjects based on Classification 1 and Classification 2 in this cross-sectional study. Results: 321 subjects with 642 eyes were involved in the study. LFT was correlated significantly with TFBUT (r = 0.14, p < 0.001). There were no significant differences between non-dry and dry eye subjects based on Classification 1 in LFT and TFBUT (p > 0.05). The difference between non-dry and dry eye subjects based on Classification 2 in LFT was not significant (p > 0.05). The value of TFBUT in dry eye subjects (3.2 ± 0.9 seconds) was significantly lower than non-dry (4.8 ± 3.1 seconds) if dry eye was defined based on Classification 2 (p < 0.001). Conclusion: Although low duration of lipid floating could cause tear instability, there were no significant correlation between the movement of lipid in non-dry and dry eye subjects.