Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism

Glycerol 1,3-diglycerolate diacrylate (GDD) was graft copolymerized onto poly(3-hydroxyoctanoate-co-3- hydroxyhexanoate) P(3HO-co-3HHX) to render the latter more hydrophilic. Grafting of P(3HO-co-3HHX) backbone was performed using benzoyl peroxide as free radical initiator in homogenous acetone so...

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Main Authors:	Ansari, Nor Faezah, Annuar, M. Suffian
Format:	Article
Language:	English English
Published:	Taylor & Francis 2017
Subjects:	QD Chemistry QH301 Biology TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/60340/ http://irep.iium.edu.my/60340/ http://irep.iium.edu.my/60340/ http://irep.iium.edu.my/60340/1/60340_Functionalization%20of%20medium-chain-length%20_article.pdf http://irep.iium.edu.my/60340/2/60340_Functionalization%20of%20medium-chain-length%20_scopus.pdf

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recordtype	eprints
spelling	iium-603402019-06-25T02:45:59Z http://irep.iium.edu.my/60340/ Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism Ansari, Nor Faezah Annuar, M. Suffian QD Chemistry QH301 Biology TP248.13 Biotechnology Glycerol 1,3-diglycerolate diacrylate (GDD) was graft copolymerized onto poly(3-hydroxyoctanoate-co-3- hydroxyhexanoate) P(3HO-co-3HHX) to render the latter more hydrophilic. Grafting of P(3HO-co-3HHX) backbone was performed using benzoyl peroxide as free radical initiator in homogenous acetone solution. The graft copolymer of P(3HO-co-3HHX)-g-GDD was characterized using spectroscopic and thermal methods. The presence of GDD monomer in the grafted P(3HO-co-3HHX) materials linked through covalent bond was indicated by spectroscopic analyses. Different parameters affecting the graft yield viz. monomer concentration, initiator concentration, temperature and reaction time were also investigated. Water uptake measurement showed that P(3HO-co-3HHX)-g-GDD copolymer became more hydrophilic as the GDD concentration in the copolymer increased. Introduction of hydroxyl groups via grafted GDD monomers improved the wettability and imparted amphiphilicity to the graft copolymer, thus potentially improving their facility for cellular interaction. Thermal stability of grafted copolymer reduced with increased grafting yield. The activation energy, Ea, for the graft copolymerization was calculated at » 51 kJ mol¡1. Mechanism of grafting reaction was also proposed. Taylor & Francis 2017-12-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/60340/1/60340_Functionalization%20of%20medium-chain-length%20_article.pdf application/pdf en http://irep.iium.edu.my/60340/2/60340_Functionalization%20of%20medium-chain-length%20_scopus.pdf Ansari, Nor Faezah and Annuar, M. Suffian (2017) Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism. Journal of Macromolecular Science: Pure and Applied Chemistry, 55 (1). pp. 66-74. ISSN 1060-1325 E-ISSN 1520-5738 http://www.tandfonline.com/doi/abs/10.1080/10601325.2017.1387490?journalCode=lmsa20 10.1080/10601325.2017.1387490
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	QD Chemistry QH301 Biology TP248.13 Biotechnology
spellingShingle	QD Chemistry QH301 Biology TP248.13 Biotechnology Ansari, Nor Faezah Annuar, M. Suffian Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism
description	Glycerol 1,3-diglycerolate diacrylate (GDD) was graft copolymerized onto poly(3-hydroxyoctanoate-co-3- hydroxyhexanoate) P(3HO-co-3HHX) to render the latter more hydrophilic. Grafting of P(3HO-co-3HHX) backbone was performed using benzoyl peroxide as free radical initiator in homogenous acetone solution. The graft copolymer of P(3HO-co-3HHX)-g-GDD was characterized using spectroscopic and thermal methods. The presence of GDD monomer in the grafted P(3HO-co-3HHX) materials linked through covalent bond was indicated by spectroscopic analyses. Different parameters affecting the graft yield viz. monomer concentration, initiator concentration, temperature and reaction time were also investigated. Water uptake measurement showed that P(3HO-co-3HHX)-g-GDD copolymer became more hydrophilic as the GDD concentration in the copolymer increased. Introduction of hydroxyl groups via grafted GDD monomers improved the wettability and imparted amphiphilicity to the graft copolymer, thus potentially improving their facility for cellular interaction. Thermal stability of grafted copolymer reduced with increased grafting yield. The activation energy, Ea, for the graft copolymerization was calculated at » 51 kJ mol¡1. Mechanism of grafting reaction was also proposed.
format	Article
author	Ansari, Nor Faezah Annuar, M. Suffian
author_facet	Ansari, Nor Faezah Annuar, M. Suffian
author_sort	Ansari, Nor Faezah
title	Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism
title_short	Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism
title_full	Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism
title_fullStr	Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism
title_full_unstemmed	Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism
title_sort	functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism
publisher	Taylor & Francis
publishDate	2017
url	http://irep.iium.edu.my/60340/ http://irep.iium.edu.my/60340/ http://irep.iium.edu.my/60340/ http://irep.iium.edu.my/60340/1/60340_Functionalization%20of%20medium-chain-length%20_article.pdf http://irep.iium.edu.my/60340/2/60340_Functionalization%20of%20medium-chain-length%20_scopus.pdf
first_indexed	2023-09-18T21:25:32Z
last_indexed	2023-09-18T21:25:32Z
_version_	1777412165882347520

Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism

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