The Islamic ethics of mitochondria transplantation

Biotechnology has opened a new chapter with the advent of mitochondria transplantation for cell-based therapy. Mitochondrial transplantation has successfully led to birth; however, cytoplasmic transplantation has caused apprehension since the mixing of human ooplasm from two different maternal sourc...

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Main Authors:	Bouzanita, Anke Iman, Mirghani, Mohamed Elwathig Saeed, Jaswir, Irwandi
Format:	Article
Language:	English English
Published:	IIUM Press 2017
Subjects:	Q Science (General) Q128 Islam and Science
Online Access:	http://irep.iium.edu.my/59882/ http://irep.iium.edu.my/59882/ http://irep.iium.edu.my/59882/1/731-3887-1-PB.pdf http://irep.iium.edu.my/59882/7/59882_The%20Islamic%20ethics%20of%20mitochondria%20transplantation_scopus.pdf

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recordtype	eprints
spelling	iium-598822018-01-24T02:53:22Z http://irep.iium.edu.my/59882/ The Islamic ethics of mitochondria transplantation Bouzanita, Anke Iman Mirghani, Mohamed Elwathig Saeed Jaswir, Irwandi Q Science (General) Q128 Islam and Science Biotechnology has opened a new chapter with the advent of mitochondria transplantation for cell-based therapy. Mitochondrial transplantation has successfully led to birth; however, cytoplasmic transplantation has caused apprehension since the mixing of human ooplasm from two different maternal sources may generate mitochondrial DNA (mtDNA) heteroplasmy in the offspring. Most Islamic legal verdicts on human cloning and somatic cell transfer are explicit as to its prohibition, due to the change of creation, mixing of lineage and other evaluations. Is mitochondria transplantation equivalent to human cloning in that genetic information is proliferated and does it, therefore, take the same legal rule? Are there possible benefits (maṣāliḥ) for medical treatment that may render mitochondria transplantation permissible, or are possible harms (mafāsid) overweighing? Or is it a completely different procedure, taking a different rule? The paper will investigate into these questions and discuss the dimensions of Islamic ethics on the issue. ABSTRAK: Bioteknologi telah membuka ruang baru pada perkembangan pemindahan mitokondria terapi berasaskan-sel. Pemindahan mitokondria telah berjaya menghasilkan kelahiran; walau bagaimanapun, pemindahan sitoplasmik telah membawa kepada masalah lain, ini kerana percampuran telur manusia (ooplasm) daripada dua induk wanita yang berbeza bakal menghasilkan mitokondrial DNA (mtDNA) yang pelbagai (heteroplasmy) dalam jalur keturunan. Kebanyakan undang-undang Islam ke atas klon manusia dan sel pemindahan somatik adalah jelas dan nyata larangannya. Ini disebabkan oleh perubahan pada ciptaan, percampuran dalam keturunan, dan pelbagai tanggapan lain. Adakah pemindahan mitokondria sama dengan klon manusia dalam informasi genetik dibiakkan dan adakah, dengan ini membawa kepada peraturan undang-undang yang sama? Adakah kemungkinan kebaikan (maṣāliḥ) pada rawatan perubatan akan menyebabkan pemindahan mitokondria dibenarkan, atau kemungkinan keburukan (mafāsid) lebih berat? Atau adakah prosedur itu benar-benar berlainan, sehingga menyebabkan hukum berbeza digunakan? Kertas ini akan mengkaji persoalan-persoalan ini dan membincangkan tentang isu ini dari sudut etika Islam. IIUM Press 2017 Article PeerReviewed application/pdf en http://irep.iium.edu.my/59882/1/731-3887-1-PB.pdf application/pdf en http://irep.iium.edu.my/59882/7/59882_The%20Islamic%20ethics%20of%20mitochondria%20transplantation_scopus.pdf Bouzanita, Anke Iman and Mirghani, Mohamed Elwathig Saeed and Jaswir, Irwandi (2017) The Islamic ethics of mitochondria transplantation. IIUM Engineering Journal, 18 (2). pp. 42-46. ISSN 1511-788X E-ISSN 2289-7860 http://journals.iium.edu.my/ejournal/index.php/iiumej/article/view/731/469
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	Q Science (General) Q128 Islam and Science
spellingShingle	Q Science (General) Q128 Islam and Science Bouzanita, Anke Iman Mirghani, Mohamed Elwathig Saeed Jaswir, Irwandi The Islamic ethics of mitochondria transplantation
description	Biotechnology has opened a new chapter with the advent of mitochondria transplantation for cell-based therapy. Mitochondrial transplantation has successfully led to birth; however, cytoplasmic transplantation has caused apprehension since the mixing of human ooplasm from two different maternal sources may generate mitochondrial DNA (mtDNA) heteroplasmy in the offspring. Most Islamic legal verdicts on human cloning and somatic cell transfer are explicit as to its prohibition, due to the change of creation, mixing of lineage and other evaluations. Is mitochondria transplantation equivalent to human cloning in that genetic information is proliferated and does it, therefore, take the same legal rule? Are there possible benefits (maṣāliḥ) for medical treatment that may render mitochondria transplantation permissible, or are possible harms (mafāsid) overweighing? Or is it a completely different procedure, taking a different rule? The paper will investigate into these questions and discuss the dimensions of Islamic ethics on the issue. ABSTRAK: Bioteknologi telah membuka ruang baru pada perkembangan pemindahan mitokondria terapi berasaskan-sel. Pemindahan mitokondria telah berjaya menghasilkan kelahiran; walau bagaimanapun, pemindahan sitoplasmik telah membawa kepada masalah lain, ini kerana percampuran telur manusia (ooplasm) daripada dua induk wanita yang berbeza bakal menghasilkan mitokondrial DNA (mtDNA) yang pelbagai (heteroplasmy) dalam jalur keturunan. Kebanyakan undang-undang Islam ke atas klon manusia dan sel pemindahan somatik adalah jelas dan nyata larangannya. Ini disebabkan oleh perubahan pada ciptaan, percampuran dalam keturunan, dan pelbagai tanggapan lain. Adakah pemindahan mitokondria sama dengan klon manusia dalam informasi genetik dibiakkan dan adakah, dengan ini membawa kepada peraturan undang-undang yang sama? Adakah kemungkinan kebaikan (maṣāliḥ) pada rawatan perubatan akan menyebabkan pemindahan mitokondria dibenarkan, atau kemungkinan keburukan (mafāsid) lebih berat? Atau adakah prosedur itu benar-benar berlainan, sehingga menyebabkan hukum berbeza digunakan? Kertas ini akan mengkaji persoalan-persoalan ini dan membincangkan tentang isu ini dari sudut etika Islam.
format	Article
author	Bouzanita, Anke Iman Mirghani, Mohamed Elwathig Saeed Jaswir, Irwandi
author_facet	Bouzanita, Anke Iman Mirghani, Mohamed Elwathig Saeed Jaswir, Irwandi
author_sort	Bouzanita, Anke Iman
title	The Islamic ethics of mitochondria transplantation
title_short	The Islamic ethics of mitochondria transplantation
title_full	The Islamic ethics of mitochondria transplantation
title_fullStr	The Islamic ethics of mitochondria transplantation
title_full_unstemmed	The Islamic ethics of mitochondria transplantation
title_sort	islamic ethics of mitochondria transplantation
publisher	IIUM Press
publishDate	2017
url	http://irep.iium.edu.my/59882/ http://irep.iium.edu.my/59882/ http://irep.iium.edu.my/59882/1/731-3887-1-PB.pdf http://irep.iium.edu.my/59882/7/59882_The%20Islamic%20ethics%20of%20mitochondria%20transplantation_scopus.pdf
first_indexed	2023-09-18T21:24:53Z
last_indexed	2023-09-18T21:24:53Z
_version_	1777412125260513280

The Islamic ethics of mitochondria transplantation

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