Effect of extraction process parameters on antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)

Acidified isopropanol extract of whole body larvae of Zophobas morio (Fabricius), which contains peptides, has been shown to exhibit an inhibitory effect towards fungal growth. The larvae, commonly known as supermeal worm are cheap and easily maintained. To make the extraction even more cost effec...

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Main Authors:	Faruck, Mohammad Omer, Yusof, Faridah, Chowdhury, Md. Sazzad Hossien
Format:	Article
Language:	English English
Published:	Faculty of Food Science & Technology, Universiti Putra Malaysia 2017
Subjects:	TP155 Chemical engineering TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/59631/ http://irep.iium.edu.my/59631/ http://irep.iium.edu.my/59631/7/59631_Effect%20of%20extraction%20process%20parameters_complete.pdf http://irep.iium.edu.my/59631/8/59631_Effect%20of%20extraction%20process%20parameters_new_scopus.pdf

id	iium-59631
recordtype	eprints
spelling	iium-596312018-04-19T08:20:32Z http://irep.iium.edu.my/59631/ Effect of extraction process parameters on antifungal peptides from Supermeal worm, Zophobas morio (Fabricius) Faruck, Mohammad Omer Yusof, Faridah Chowdhury, Md. Sazzad Hossien TP155 Chemical engineering TP248.13 Biotechnology Acidified isopropanol extract of whole body larvae of Zophobas morio (Fabricius), which contains peptides, has been shown to exhibit an inhibitory effect towards fungal growth. The larvae, commonly known as supermeal worm are cheap and easily maintained. To make the extraction even more cost effective, it is pertinent to maximize the extraction yield and to optimize the extraction process. The aim of this study is to use the One-Factor-At-a-Time (OFAT) strategy to determine the maximum values of the process parameters for the extraction of antifungal peptides, where these values can later be used in the experimental design to optimize the extraction process. Based on importance, three parameters were selected, namely, initial homogenization temperature, homogenization time and solid (g) to solvent (ml) ratio. Maximum inhibition to fungal growth was found when the extraction was carried out as follows; using initial homogenization temperature of 4°C, homogenization time of 5 minutes and a solid (g) to solvent (ml) ratio of 3.5:1. The peptide extract displayed different degree of antifungal effect towards four selected fungi, Aspergillus niger, Microsporum canis, Candida albicans and Blastomyces dermatitidsis. Faculty of Food Science & Technology, Universiti Putra Malaysia 2017 Article PeerReviewed application/pdf en http://irep.iium.edu.my/59631/7/59631_Effect%20of%20extraction%20process%20parameters_complete.pdf application/pdf en http://irep.iium.edu.my/59631/8/59631_Effect%20of%20extraction%20process%20parameters_new_scopus.pdf Faruck, Mohammad Omer and Yusof, Faridah and Chowdhury, Md. Sazzad Hossien (2017) Effect of extraction process parameters on antifungal peptides from Supermeal worm, Zophobas morio (Fabricius). International Food Research Journal (IFRJ), 24 (Suppl.). pp. 463-467. ISSN 1985-4668 E-ISSN 2231-7546 http://www.ifrj.upm.edu.my/24%20(07)%202017%20supplementary/(32)%20R1.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	TP155 Chemical engineering TP248.13 Biotechnology
spellingShingle	TP155 Chemical engineering TP248.13 Biotechnology Faruck, Mohammad Omer Yusof, Faridah Chowdhury, Md. Sazzad Hossien Effect of extraction process parameters on antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)
description	Acidified isopropanol extract of whole body larvae of Zophobas morio (Fabricius), which contains peptides, has been shown to exhibit an inhibitory effect towards fungal growth. The larvae, commonly known as supermeal worm are cheap and easily maintained. To make the extraction even more cost effective, it is pertinent to maximize the extraction yield and to optimize the extraction process. The aim of this study is to use the One-Factor-At-a-Time (OFAT) strategy to determine the maximum values of the process parameters for the extraction of antifungal peptides, where these values can later be used in the experimental design to optimize the extraction process. Based on importance, three parameters were selected, namely, initial homogenization temperature, homogenization time and solid (g) to solvent (ml) ratio. Maximum inhibition to fungal growth was found when the extraction was carried out as follows; using initial homogenization temperature of 4°C, homogenization time of 5 minutes and a solid (g) to solvent (ml) ratio of 3.5:1. The peptide extract displayed different degree of antifungal effect towards four selected fungi, Aspergillus niger, Microsporum canis, Candida albicans and Blastomyces dermatitidsis.
format	Article
author	Faruck, Mohammad Omer Yusof, Faridah Chowdhury, Md. Sazzad Hossien
author_facet	Faruck, Mohammad Omer Yusof, Faridah Chowdhury, Md. Sazzad Hossien
author_sort	Faruck, Mohammad Omer
title	Effect of extraction process parameters on antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)
title_short	Effect of extraction process parameters on antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)
title_full	Effect of extraction process parameters on antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)
title_fullStr	Effect of extraction process parameters on antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)
title_full_unstemmed	Effect of extraction process parameters on antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)
title_sort	effect of extraction process parameters on antifungal peptides from supermeal worm, zophobas morio (fabricius)
publisher	Faculty of Food Science & Technology, Universiti Putra Malaysia
publishDate	2017
url	http://irep.iium.edu.my/59631/ http://irep.iium.edu.my/59631/ http://irep.iium.edu.my/59631/7/59631_Effect%20of%20extraction%20process%20parameters_complete.pdf http://irep.iium.edu.my/59631/8/59631_Effect%20of%20extraction%20process%20parameters_new_scopus.pdf
first_indexed	2023-09-18T21:24:29Z
last_indexed	2023-09-18T21:24:29Z
_version_	1777412100109369344

Effect of extraction process parameters on antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)

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