Total phenolic content, antioxidative and antidiabetic properties of coconut (Cocos Nucifera L.) testa and selected bean seed coats

Natural alternatives for the treatment of diabetes mellitus have been the interest of many researchers. In this study, the brown testas of mature coconuts were compared to beans seed coats of four varieties in terms of antioxidative and anti-hyperglycaemic properties. The total phenolic and flavonoi...

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Main Authors:	Adekola, Kehinde Adedeji, Salleh, Abu Bakar, Zaidan, Uswatun Hasanah, Azlan, Azrina, Chiavaro, Emma, Paciulli, Maria, Marikkar, Nazrim
Format:	Article
Language:	English English
Published:	Chiriotti Editori 2017
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/59586/ http://irep.iium.edu.my/59586/ http://irep.iium.edu.my/59586/1/PAPER-Print%20version.pdf http://irep.iium.edu.my/59586/7/59586_Total%20phenolic%20content%2C%20antioxidative%20and%20antidiabetic_scopus.pdf

id	iium-59586
recordtype	eprints
spelling	iium-595862017-11-20T02:52:33Z http://irep.iium.edu.my/59586/ Total phenolic content, antioxidative and antidiabetic properties of coconut (Cocos Nucifera L.) testa and selected bean seed coats Adekola, Kehinde Adedeji Salleh, Abu Bakar Zaidan, Uswatun Hasanah Azlan, Azrina Chiavaro, Emma Paciulli, Maria Marikkar, Nazrim QD Chemistry Natural alternatives for the treatment of diabetes mellitus have been the interest of many researchers. In this study, the brown testas of mature coconuts were compared to beans seed coats of four varieties in terms of antioxidative and anti-hyperglycaemic properties. The total phenolic and flavonoid contents, the antioxidant potentials and the α-amylase and α-glucosidase inhibitory activities of the crude extracts were studied in vitro. The results showed that extracts of coconut testa and red kidney bean seed coat displayed higher α-glucosidase inhibition (IC50=19.90±5.67 and 4.84±1.43 µg/ml) and α-amylase inhibition (IC50=120.5±15.4 and 532.8±68.0 µg/ml) than the other extracts. These two extracts showed higher antioxidant capacities owing to their high phenolic and flavonoid contents. These results suggest that red kidney bean seed coat and coconut testa would have higher potential as nutraceuticals and could serve as natural alternative sources of anti-diabetic remedy. Chiriotti Editori 2017-10-24 Article PeerReviewed application/pdf en http://irep.iium.edu.my/59586/1/PAPER-Print%20version.pdf application/pdf en http://irep.iium.edu.my/59586/7/59586_Total%20phenolic%20content%2C%20antioxidative%20and%20antidiabetic_scopus.pdf Adekola, Kehinde Adedeji and Salleh, Abu Bakar and Zaidan, Uswatun Hasanah and Azlan, Azrina and Chiavaro, Emma and Paciulli, Maria and Marikkar, Nazrim (2017) Total phenolic content, antioxidative and antidiabetic properties of coconut (Cocos Nucifera L.) testa and selected bean seed coats. Italian Journal of Food Science, 29 (4). pp. 741-753. ISSN 1120-1770 E-ISSN 2239-5687 http://www.chiriottieditori.it/ojs/index.php/ijfs/article/view/941
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	QD Chemistry
spellingShingle	QD Chemistry Adekola, Kehinde Adedeji Salleh, Abu Bakar Zaidan, Uswatun Hasanah Azlan, Azrina Chiavaro, Emma Paciulli, Maria Marikkar, Nazrim Total phenolic content, antioxidative and antidiabetic properties of coconut (Cocos Nucifera L.) testa and selected bean seed coats
description	Natural alternatives for the treatment of diabetes mellitus have been the interest of many researchers. In this study, the brown testas of mature coconuts were compared to beans seed coats of four varieties in terms of antioxidative and anti-hyperglycaemic properties. The total phenolic and flavonoid contents, the antioxidant potentials and the α-amylase and α-glucosidase inhibitory activities of the crude extracts were studied in vitro. The results showed that extracts of coconut testa and red kidney bean seed coat displayed higher α-glucosidase inhibition (IC50=19.90±5.67 and 4.84±1.43 µg/ml) and α-amylase inhibition (IC50=120.5±15.4 and 532.8±68.0 µg/ml) than the other extracts. These two extracts showed higher antioxidant capacities owing to their high phenolic and flavonoid contents. These results suggest that red kidney bean seed coat and coconut testa would have higher potential as nutraceuticals and could serve as natural alternative sources of anti-diabetic remedy.
format	Article
author	Adekola, Kehinde Adedeji Salleh, Abu Bakar Zaidan, Uswatun Hasanah Azlan, Azrina Chiavaro, Emma Paciulli, Maria Marikkar, Nazrim
author_facet	Adekola, Kehinde Adedeji Salleh, Abu Bakar Zaidan, Uswatun Hasanah Azlan, Azrina Chiavaro, Emma Paciulli, Maria Marikkar, Nazrim
author_sort	Adekola, Kehinde Adedeji
title	Total phenolic content, antioxidative and antidiabetic properties of coconut (Cocos Nucifera L.) testa and selected bean seed coats
title_short	Total phenolic content, antioxidative and antidiabetic properties of coconut (Cocos Nucifera L.) testa and selected bean seed coats
title_full	Total phenolic content, antioxidative and antidiabetic properties of coconut (Cocos Nucifera L.) testa and selected bean seed coats
title_fullStr	Total phenolic content, antioxidative and antidiabetic properties of coconut (Cocos Nucifera L.) testa and selected bean seed coats
title_full_unstemmed	Total phenolic content, antioxidative and antidiabetic properties of coconut (Cocos Nucifera L.) testa and selected bean seed coats
title_sort	total phenolic content, antioxidative and antidiabetic properties of coconut (cocos nucifera l.) testa and selected bean seed coats
publisher	Chiriotti Editori
publishDate	2017
url	http://irep.iium.edu.my/59586/ http://irep.iium.edu.my/59586/ http://irep.iium.edu.my/59586/1/PAPER-Print%20version.pdf http://irep.iium.edu.my/59586/7/59586_Total%20phenolic%20content%2C%20antioxidative%20and%20antidiabetic_scopus.pdf
first_indexed	2023-09-18T21:24:26Z
last_indexed	2023-09-18T21:24:26Z
_version_	1777412096442499072

Total phenolic content, antioxidative and antidiabetic properties of coconut (Cocos Nucifera L.) testa and selected bean seed coats

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