Cytopathological effects of smoking on clinically normal oral mucosa

Introduction: Smoking is a well-known cause of oral disease and oral cancer. Several dysplastic cytological changes occur before the appearance of the clinical lesion. This study aimed to investigate the cytopathological effects of smoking in clinically normal oral mucosa of cigarette smokers. Mater...

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Main Authors:	Faisal, Ghasak Ghazi, Khalid, Faridah, Yazid, Yusri
Format:	Conference or Workshop Item
Language:	English
Published:	2017
Subjects:	RB Pathology RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
Online Access:	http://irep.iium.edu.my/59178/ http://irep.iium.edu.my/59178/ http://irep.iium.edu.my/59178/22/59178-Cytopathological%20Effects%20Of%20Smoking.pdf

id	iium-59178
recordtype	eprints
spelling	iium-591782017-11-27T03:36:43Z http://irep.iium.edu.my/59178/ Cytopathological effects of smoking on clinically normal oral mucosa Faisal, Ghasak Ghazi Khalid, Faridah Yazid, Yusri RB Pathology RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works Introduction: Smoking is a well-known cause of oral disease and oral cancer. Several dysplastic cytological changes occur before the appearance of the clinical lesion. This study aimed to investigate the cytopathological effects of smoking in clinically normal oral mucosa of cigarette smokers. Materials and methods: A total of 40 cigarette smokers and 40 nonsmokers (control group) were included in this study. All participants had clinically normal oral mucosa. Oral smears were obtained from the side of the tongue and floor of the mouth using a Cytobrush. The smears were stained by Papanicolaou stain and examined under light microscope for inflammation, hyperkeratinization and dysplasia. Results: There was a significantly higher rate(p<0.005) of inflammation 63%, hyperkeratiniztion 62% and mild dysplasia 26% among smokers than non-smokers where the rates were 35%, 12% and 2% respectively. Conclusion: Smoking causes significant cytopathological changes in normal oral mucosa, the detection of which is important to prevent progression into carcinoma. The procedure is fast, painless and inexpensive. 2017 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/59178/22/59178-Cytopathological%20Effects%20Of%20Smoking.pdf Faisal, Ghasak Ghazi and Khalid, Faridah and Yazid, Yusri (2017) Cytopathological effects of smoking on clinically normal oral mucosa. In: 1st IIUM International Dental Conference 2017 in Commemoration of the Kulliyyah of Dentistry 10th Anniversary (1st IIDC), 6th-8th October 2017, Kuantan, Pahang. (Unpublished) http://iidc.com.my/wp-content/uploads/2017/09/IIDC-eBook.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RB Pathology RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
spellingShingle	RB Pathology RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works Faisal, Ghasak Ghazi Khalid, Faridah Yazid, Yusri Cytopathological effects of smoking on clinically normal oral mucosa
description	Introduction: Smoking is a well-known cause of oral disease and oral cancer. Several dysplastic cytological changes occur before the appearance of the clinical lesion. This study aimed to investigate the cytopathological effects of smoking in clinically normal oral mucosa of cigarette smokers. Materials and methods: A total of 40 cigarette smokers and 40 nonsmokers (control group) were included in this study. All participants had clinically normal oral mucosa. Oral smears were obtained from the side of the tongue and floor of the mouth using a Cytobrush. The smears were stained by Papanicolaou stain and examined under light microscope for inflammation, hyperkeratinization and dysplasia. Results: There was a significantly higher rate(p<0.005) of inflammation 63%, hyperkeratiniztion 62% and mild dysplasia 26% among smokers than non-smokers where the rates were 35%, 12% and 2% respectively. Conclusion: Smoking causes significant cytopathological changes in normal oral mucosa, the detection of which is important to prevent progression into carcinoma. The procedure is fast, painless and inexpensive.
format	Conference or Workshop Item
author	Faisal, Ghasak Ghazi Khalid, Faridah Yazid, Yusri
author_facet	Faisal, Ghasak Ghazi Khalid, Faridah Yazid, Yusri
author_sort	Faisal, Ghasak Ghazi
title	Cytopathological effects of smoking on clinically normal oral mucosa
title_short	Cytopathological effects of smoking on clinically normal oral mucosa
title_full	Cytopathological effects of smoking on clinically normal oral mucosa
title_fullStr	Cytopathological effects of smoking on clinically normal oral mucosa
title_full_unstemmed	Cytopathological effects of smoking on clinically normal oral mucosa
title_sort	cytopathological effects of smoking on clinically normal oral mucosa
publishDate	2017
url	http://irep.iium.edu.my/59178/ http://irep.iium.edu.my/59178/ http://irep.iium.edu.my/59178/22/59178-Cytopathological%20Effects%20Of%20Smoking.pdf
first_indexed	2023-09-18T21:23:47Z
last_indexed	2023-09-18T21:23:47Z
_version_	1777412056444567552

Cytopathological effects of smoking on clinically normal oral mucosa

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