Immunomodulatory effect of alginic acid from brown seaweed sargassum wightii on disease resistance in penaeus monodon
In recent days, bacterial diseases are very common among all the aquatic organisms. Particularly in grow out ponds they cause heavy loss in aquaculture. To overcome this problem, the use of antibiotics become a common practice, thus leads to the development of antibiotic resistant strains. In this...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
RAZI Publishing
2017
|
| Subjects: | |
| Online Access: | http://irep.iium.edu.my/58913/ http://irep.iium.edu.my/58913/ http://irep.iium.edu.my/58913/1/58913_Immunomodulatory%20Effect%20of%20Alginic_article.pdf |
| Summary: | In recent days, bacterial diseases are very common among all the aquatic organisms. Particularly in grow out
ponds they cause heavy loss in aquaculture. To overcome this problem, the use of antibiotics become a common
practice, thus leads to the development of antibiotic resistant strains. In this regard, a new attempt has been made
to study the immunostimulatory effect of alginic acid, a sulphated polysaccharide derived from brown seaweed
Sargassum wightii, on the disease resistance in Penaeus monodon. The immunological parameters, such as Total
Haemocyte Count (THC), Prophenoloxidase activity, Respiratory burst (NBT assay), Superoxide dismutase activity
and Phagocytic activity were monitored after challenging against Vibrio parahaemolyticus. Before the challenge
study, the test animals were fed with different concentrations (1,2,3 g/kg as A1, A2, A3) of alginic acid fed diet
for 45 days. All the immunological parameters showed a significant increase with an increasing concentration of
alginic acid, in the test animals compared to the control throughout the experimental study period. |
|---|