α-Glucosidase inhibitory activity of selected Malaysian plants

Diabetes is a common metabolic disease indicated by unusually high plasma glucose level that can lead to major complications such as diabetic neuropathy, retinopathy, and cardiovascular diseases. One of the effective therapeutic managements of the disease is to reduce postprandial hyperglycemia thr...

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Main Authors:	Mohd Bukhari, Dzatil Awanis, Siddiqui, Mohammad Jamshed Ahmad, Shamsudin, Siti Hadijah, Rahman, Md. Mokhlesur, Mat So'ad, Siti Zaiton
Format:	Article
Language:	English English
Published:	Wolters Kluwer 2017
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/58365/ http://irep.iium.edu.my/58365/ http://irep.iium.edu.my/58365/1/JPBS_2017_alpha%20Glucosidase.pdf http://irep.iium.edu.my/58365/7/58365_%CE%B1-Glucosidase%20inhibitory%20activity%20of%20selected%20Malaysian%20plants_SCOPUS.pdf

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recordtype	eprints
spelling	iium-583652018-01-05T07:10:00Z http://irep.iium.edu.my/58365/ α-Glucosidase inhibitory activity of selected Malaysian plants Mohd Bukhari, Dzatil Awanis Siddiqui, Mohammad Jamshed Ahmad Shamsudin, Siti Hadijah Rahman, Md. Mokhlesur Mat So'ad, Siti Zaiton QD Chemistry Diabetes is a common metabolic disease indicated by unusually high plasma glucose level that can lead to major complications such as diabetic neuropathy, retinopathy, and cardiovascular diseases. One of the effective therapeutic managements of the disease is to reduce postprandial hyperglycemia through inhibition of α-glucosidase, a carbohydratehydrolyzing enzyme to retard overall glucose absorption. In recent years, a plenty of research works have been conducted looking for novel and effective α-glucosidase inhibitors (AGIs) from natural sources as alternatives for the synthetic AGI due to their unpleasant side effects. Plants and herbs are rich with secondary metabolites that have massive pharmaceutical potential. Besides, studies showed that phytochemicals such as flavonoids, alkaloids, terpenoids, anthocyanins, glycosides, and phenolic compounds possess significant inhibitory activity against α-glucosidase enzyme. Malaysia is a tropical country that is rich with medicinal herbs. In this review, we focus on eight Malaysian plants with the potential as AGI to develop a potential functional food or lead compounds against diabetes. Wolters Kluwer 2017-06 Article PeerReviewed application/pdf en http://irep.iium.edu.my/58365/1/JPBS_2017_alpha%20Glucosidase.pdf application/pdf en http://irep.iium.edu.my/58365/7/58365_%CE%B1-Glucosidase%20inhibitory%20activity%20of%20selected%20Malaysian%20plants_SCOPUS.pdf Mohd Bukhari, Dzatil Awanis and Siddiqui, Mohammad Jamshed Ahmad and Shamsudin, Siti Hadijah and Rahman, Md. Mokhlesur and Mat So'ad, Siti Zaiton (2017) α-Glucosidase inhibitory activity of selected Malaysian plants. Journal of Pharmacy And Bioallied Sciences, 9 (3 (June-September 2017)). pp. 164-170. ISSN 0975-7406 http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2017;volume=9;issue=3;spage=164;epage=170;aulast=Mohd;type=0
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	QD Chemistry
spellingShingle	QD Chemistry Mohd Bukhari, Dzatil Awanis Siddiqui, Mohammad Jamshed Ahmad Shamsudin, Siti Hadijah Rahman, Md. Mokhlesur Mat So'ad, Siti Zaiton α-Glucosidase inhibitory activity of selected Malaysian plants
description	Diabetes is a common metabolic disease indicated by unusually high plasma glucose level that can lead to major complications such as diabetic neuropathy, retinopathy, and cardiovascular diseases. One of the effective therapeutic managements of the disease is to reduce postprandial hyperglycemia through inhibition of α-glucosidase, a carbohydratehydrolyzing enzyme to retard overall glucose absorption. In recent years, a plenty of research works have been conducted looking for novel and effective α-glucosidase inhibitors (AGIs) from natural sources as alternatives for the synthetic AGI due to their unpleasant side effects. Plants and herbs are rich with secondary metabolites that have massive pharmaceutical potential. Besides, studies showed that phytochemicals such as flavonoids, alkaloids, terpenoids, anthocyanins, glycosides, and phenolic compounds possess significant inhibitory activity against α-glucosidase enzyme. Malaysia is a tropical country that is rich with medicinal herbs. In this review, we focus on eight Malaysian plants with the potential as AGI to develop a potential functional food or lead compounds against diabetes.
format	Article
author	Mohd Bukhari, Dzatil Awanis Siddiqui, Mohammad Jamshed Ahmad Shamsudin, Siti Hadijah Rahman, Md. Mokhlesur Mat So'ad, Siti Zaiton
author_facet	Mohd Bukhari, Dzatil Awanis Siddiqui, Mohammad Jamshed Ahmad Shamsudin, Siti Hadijah Rahman, Md. Mokhlesur Mat So'ad, Siti Zaiton
author_sort	Mohd Bukhari, Dzatil Awanis
title	α-Glucosidase inhibitory activity of selected Malaysian plants
title_short	α-Glucosidase inhibitory activity of selected Malaysian plants
title_full	α-Glucosidase inhibitory activity of selected Malaysian plants
title_fullStr	α-Glucosidase inhibitory activity of selected Malaysian plants
title_full_unstemmed	α-Glucosidase inhibitory activity of selected Malaysian plants
title_sort	α-glucosidase inhibitory activity of selected malaysian plants
publisher	Wolters Kluwer
publishDate	2017
url	http://irep.iium.edu.my/58365/ http://irep.iium.edu.my/58365/ http://irep.iium.edu.my/58365/1/JPBS_2017_alpha%20Glucosidase.pdf http://irep.iium.edu.my/58365/7/58365_%CE%B1-Glucosidase%20inhibitory%20activity%20of%20selected%20Malaysian%20plants_SCOPUS.pdf
first_indexed	2023-09-18T21:22:31Z
last_indexed	2023-09-18T21:22:31Z
_version_	1777411976471773184

α-Glucosidase inhibitory activity of selected Malaysian plants

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