Performance of glycemic control protocol and virtual trial
Model-based glycemic control offers direct management of patient-specific variability and better adaptive control. Implementation of the model-based glycemic control has the potential to reduce hyperglycemia episodes, mortality and morbidity as seen in some successful TGC. The design of any TGC must...
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iium-581532019-01-03T07:13:18Z http://irep.iium.edu.my/58153/ Performance of glycemic control protocol and virtual trial Suhaimi, Fatanah M. Abdul Razak, Normy Norfiza Md Ralib, Azrina Mat Nor, Mohd Basri R Medicine (General) Model-based glycemic control offers direct management of patient-specific variability and better adaptive control. Implementation of the model-based glycemic control has the potential to reduce hyperglycemia episodes, mortality and morbidity as seen in some successful TGC. The design of any TGC must consider not only the glycemic target range but also safety and efficacy of the insulin therapy. This paper presents the evaluation of glycemic control protocol adapted in the ICU of Tengku Ampuan Afzan Hospital. Virtual trials method is used to simulate the controller algorithm on a virtual patient with feed variation factor. Data from actual clinical and the virtual trial are compared to analyze the protocol performance concerning blood glucose outcome and insulin efficacy. A stochastic model is also used to indicate metabolic response and metabolic variation of the cohort. American Scientific Publishers 2017-08-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/58153/1/I4CT%20Virtual%20Trial%20Fath.pdf application/pdf en http://irep.iium.edu.my/58153/7/58153_Performance%20of%20Glycemic_MYRA.pdf application/pdf en http://irep.iium.edu.my/58153/13/58153_Performance%20of%20glycemic%20control%20protocol_scopus.pdf Suhaimi, Fatanah M. and Abdul Razak, Normy Norfiza and Md Ralib, Azrina and Mat Nor, Mohd Basri (2017) Performance of glycemic control protocol and virtual trial. Advanced Science Letters, 23 (6). pp. 5415-5418. ISSN 1936-6612 E-ISSN 1936-7317 http://www.ingentaconnect.com/content/asp/asl/2017/00000023/00000006/art00089 |
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R Medicine (General) Suhaimi, Fatanah M. Abdul Razak, Normy Norfiza Md Ralib, Azrina Mat Nor, Mohd Basri Performance of glycemic control protocol and virtual trial |
description |
Model-based glycemic control offers direct management of patient-specific variability and better adaptive control. Implementation of the model-based glycemic control has the potential to reduce hyperglycemia episodes, mortality and morbidity as seen in some successful TGC. The design of any TGC must consider not only the glycemic target range but also safety and efficacy of the insulin therapy. This paper presents the evaluation of glycemic control protocol adapted in the ICU of Tengku Ampuan Afzan Hospital. Virtual trials method is used to simulate the controller algorithm on a virtual patient with feed variation factor. Data from actual clinical and the virtual trial are compared to analyze the protocol performance concerning blood glucose outcome and insulin efficacy. A stochastic model is also used to indicate metabolic response and metabolic variation of the cohort. |
format |
Article |
author |
Suhaimi, Fatanah M. Abdul Razak, Normy Norfiza Md Ralib, Azrina Mat Nor, Mohd Basri |
author_facet |
Suhaimi, Fatanah M. Abdul Razak, Normy Norfiza Md Ralib, Azrina Mat Nor, Mohd Basri |
author_sort |
Suhaimi, Fatanah M. |
title |
Performance of glycemic control protocol and virtual trial |
title_short |
Performance of glycemic control protocol and virtual trial |
title_full |
Performance of glycemic control protocol and virtual trial |
title_fullStr |
Performance of glycemic control protocol and virtual trial |
title_full_unstemmed |
Performance of glycemic control protocol and virtual trial |
title_sort |
performance of glycemic control protocol and virtual trial |
publisher |
American Scientific Publishers |
publishDate |
2017 |
url |
http://irep.iium.edu.my/58153/ http://irep.iium.edu.my/58153/ http://irep.iium.edu.my/58153/1/I4CT%20Virtual%20Trial%20Fath.pdf http://irep.iium.edu.my/58153/7/58153_Performance%20of%20Glycemic_MYRA.pdf http://irep.iium.edu.my/58153/13/58153_Performance%20of%20glycemic%20control%20protocol_scopus.pdf |
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2023-09-18T21:22:12Z |
last_indexed |
2023-09-18T21:22:12Z |
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1777411956771127296 |