Mutation of arginine residues to avoid non-specific cellular uptakes for hepatitis B virus core particles
BACKGROUND: The hepatitis B virus core (HBc) particle is known as a promising new carrier for the delivery of drugs and nucleic acids. However, since the arginine-rich domain that is located in the C-terminal region of the HBc monomer binds to the heparan sulphate proteoglycan on the cell surface du...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Biomed Central
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/57364/ http://irep.iium.edu.my/57364/ http://irep.iium.edu.my/57364/1/Suffian%20et%20al.%20Journal%20of%20Nanobiotechnology.pdf |