Identification of Beta Human Chorionic Gonadotrophin (BHcg) expression in frozen cleavage embryo of in vitro fertilization (Ivf) patients: an essential approach for better outcome towards human being inheritance in line with Maqasid Syari’ah concept

Identification of Beta Human Chorionic Gonadotrophin (BHcg) expression in frozen cleavage embryo of in vitro fertilization (Ivf) patients: an essential approach for better outcome towards human being inheritance in line with Maqasid Syari’ah concept

Expression of beta-human chorionic gonadotropin (BHCG) mRNA in early cleavage cell stages is important in predicting embryo viability at blastocyst stage of development. Embryo viability is crucial for in vitro fertilization (IVF) treatment to be succeeded in terms of increment of implantation and p...

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Main Authors: Mat Yusof, Afzan, Md Isa, Muhammad Lokman, Ramli, Roszaman, Abdul Wahab, Azantee Yazmie
Format: Conference or Workshop Item
Language:English
English
Published: International Islamic University Malaysia 2016
Subjects:
Q Science (General)
Online Access:http://irep.iium.edu.my/56824/
http://irep.iium.edu.my/56824/
http://irep.iium.edu.my/56824/1/Conference%202WCII2016%201.pdf
http://irep.iium.edu.my/56824/12/56824_Identification%20of%20beta%20human%20chorionic%20gonadotrophin_SCOPUS%202016.pdf
id iium-56824
recordtype eprints
spelling iium-568242019-06-25T02:08:29Z http://irep.iium.edu.my/56824/ Identification of Beta Human Chorionic Gonadotrophin (BHcg) expression in frozen cleavage embryo of in vitro fertilization (Ivf) patients: an essential approach for better outcome towards human being inheritance in line with Maqasid Syari’ah concept Mat Yusof, Afzan Md Isa, Muhammad Lokman Ramli, Roszaman Abdul Wahab, Azantee Yazmie Q Science (General) Expression of beta-human chorionic gonadotropin (BHCG) mRNA in early cleavage cell stages is important in predicting embryo viability at blastocyst stage of development. Embryo viability is crucial for in vitro fertilization (IVF) treatment to be succeeded in terms of increment of implantation and pregnancy rate. In order to establish fertilization outside the human body, we should ensure the condition is optimum and as closer as inside the body in term of time and also the chemical processes that involved including hormones and growth factors. Imam Muslim narrated from Hudhayfa ibn Asad that the Prophet Muhammad (s.a.w.) said: “After the sperm-and-ovum drop (nut.fa) has been [in the uterus] fortytwo days, Allah sends it an angel that gives it form and fashions its hearing, sight, skin, flesh, and skeleton.” Therefore the aim of this study is to find the significant association of BHCG expression with early cell stage cleavages and its relationship as predictive marker for potential embryo implantation. Our study focuses on leftover frozen embryos from eight patients consists of six pregnant patients and two non-pregnant patients. We assessed the human BHCG mRNA expression at different cell cleavage stages in these frozen embryos using reverse transcriptase-polymerase chain reaction (RT-PCR). Our results have shown three out of eight patients with five to ten cells of blastomeres were expressed with BHCG. This study indicated that BHCG was expressed on frozethawed late cleavage stage of embryos in IVF patients. International Islamic University Malaysia 2016-10-21 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/56824/1/Conference%202WCII2016%201.pdf application/pdf en http://irep.iium.edu.my/56824/12/56824_Identification%20of%20beta%20human%20chorionic%20gonadotrophin_SCOPUS%202016.pdf Mat Yusof, Afzan and Md Isa, Muhammad Lokman and Ramli, Roszaman and Abdul Wahab, Azantee Yazmie (2016) Identification of Beta Human Chorionic Gonadotrophin (BHcg) expression in frozen cleavage embryo of in vitro fertilization (Ivf) patients: an essential approach for better outcome towards human being inheritance in line with Maqasid Syari’ah concept. In: 2nd World Congress on Integration and Islamicisation: Focus on Medical and Health Care Sciences (2WCII 2016), 21st-23rd Oct. 2016, Kuantan, Pahang Darul Makmur. http://www.iium.edu.my/wcii/
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic Q Science (General)
spellingShingle Q Science (General)
Mat Yusof, Afzan
Md Isa, Muhammad Lokman
Ramli, Roszaman
Abdul Wahab, Azantee Yazmie
Identification of Beta Human Chorionic Gonadotrophin (BHcg) expression in frozen cleavage embryo of in vitro fertilization (Ivf) patients: an essential approach for better outcome towards human being inheritance in line with Maqasid Syari’ah concept
description Expression of beta-human chorionic gonadotropin (BHCG) mRNA in early cleavage cell stages is important in predicting embryo viability at blastocyst stage of development. Embryo viability is crucial for in vitro fertilization (IVF) treatment to be succeeded in terms of increment of implantation and pregnancy rate. In order to establish fertilization outside the human body, we should ensure the condition is optimum and as closer as inside the body in term of time and also the chemical processes that involved including hormones and growth factors. Imam Muslim narrated from Hudhayfa ibn Asad that the Prophet Muhammad (s.a.w.) said: “After the sperm-and-ovum drop (nut.fa) has been [in the uterus] fortytwo days, Allah sends it an angel that gives it form and fashions its hearing, sight, skin, flesh, and skeleton.” Therefore the aim of this study is to find the significant association of BHCG expression with early cell stage cleavages and its relationship as predictive marker for potential embryo implantation. Our study focuses on leftover frozen embryos from eight patients consists of six pregnant patients and two non-pregnant patients. We assessed the human BHCG mRNA expression at different cell cleavage stages in these frozen embryos using reverse transcriptase-polymerase chain reaction (RT-PCR). Our results have shown three out of eight patients with five to ten cells of blastomeres were expressed with BHCG. This study indicated that BHCG was expressed on frozethawed late cleavage stage of embryos in IVF patients.
format Conference or Workshop Item
author Mat Yusof, Afzan
Md Isa, Muhammad Lokman
Ramli, Roszaman
Abdul Wahab, Azantee Yazmie
author_facet Mat Yusof, Afzan
Md Isa, Muhammad Lokman
Ramli, Roszaman
Abdul Wahab, Azantee Yazmie
author_sort Mat Yusof, Afzan
title Identification of Beta Human Chorionic Gonadotrophin (BHcg) expression in frozen cleavage embryo of in vitro fertilization (Ivf) patients: an essential approach for better outcome towards human being inheritance in line with Maqasid Syari’ah concept
title_short Identification of Beta Human Chorionic Gonadotrophin (BHcg) expression in frozen cleavage embryo of in vitro fertilization (Ivf) patients: an essential approach for better outcome towards human being inheritance in line with Maqasid Syari’ah concept
title_full Identification of Beta Human Chorionic Gonadotrophin (BHcg) expression in frozen cleavage embryo of in vitro fertilization (Ivf) patients: an essential approach for better outcome towards human being inheritance in line with Maqasid Syari’ah concept
title_fullStr Identification of Beta Human Chorionic Gonadotrophin (BHcg) expression in frozen cleavage embryo of in vitro fertilization (Ivf) patients: an essential approach for better outcome towards human being inheritance in line with Maqasid Syari’ah concept
title_full_unstemmed Identification of Beta Human Chorionic Gonadotrophin (BHcg) expression in frozen cleavage embryo of in vitro fertilization (Ivf) patients: an essential approach for better outcome towards human being inheritance in line with Maqasid Syari’ah concept
title_sort identification of beta human chorionic gonadotrophin (bhcg) expression in frozen cleavage embryo of in vitro fertilization (ivf) patients: an essential approach for better outcome towards human being inheritance in line with maqasid syari’ah concept
publisher International Islamic University Malaysia
publishDate 2016
url http://irep.iium.edu.my/56824/
http://irep.iium.edu.my/56824/
http://irep.iium.edu.my/56824/1/Conference%202WCII2016%201.pdf
http://irep.iium.edu.my/56824/12/56824_Identification%20of%20beta%20human%20chorionic%20gonadotrophin_SCOPUS%202016.pdf
first_indexed 2023-09-18T21:20:13Z
last_indexed 2023-09-18T21:20:13Z
_version_ 1777411831666573312

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