Performance of blood glucose management protocols in HTAA intensive care unit

Abstract—Insulin Infusion Therapy (IIT) has been implemented in Malaysia Intensive Care Unit (ICU) for decades to control blood glucose level (BGL) among critically ill patients. In this study, clinical data of 210 patients treated with IIT-HTAA protocol and the minimum length of stay of 1 day were...

Full description

Bibliographic Details
Main Authors: Humaidi, M. Luqman, WM Zulkifly, W Zuhriraihan, Rosly, C. Zafirah, Khalid, Khalijah, Jamaludin, Ummu Kulthum, Md Ralib, Azrina, Mat Nor, Mohd. Basri
Format: Conference or Workshop Item
Language:English
English
Published: Institute of Electrical and Electronics Engineers Inc. 2016
Subjects:
Online Access:http://irep.iium.edu.my/56708/
http://irep.iium.edu.my/56708/
http://irep.iium.edu.my/56708/
http://irep.iium.edu.my/56708/1/56708_I2CACIS.pdf
http://irep.iium.edu.my/56708/2/56708_I2CACIS_SCOPUS.pdf
id iium-56708
recordtype eprints
spelling iium-567082017-10-17T03:35:39Z http://irep.iium.edu.my/56708/ Performance of blood glucose management protocols in HTAA intensive care unit Humaidi, M. Luqman WM Zulkifly, W Zuhriraihan Rosly, C. Zafirah Khalid, Khalijah Jamaludin, Ummu Kulthum Md Ralib, Azrina Mat Nor, Mohd. Basri R Medicine (General) Abstract—Insulin Infusion Therapy (IIT) has been implemented in Malaysia Intensive Care Unit (ICU) for decades to control blood glucose level (BGL) among critically ill patients. In this study, clinical data of 210 patients treated with IIT-HTAA protocol and the minimum length of stay of 1 day were analysed. BGL, insulin and nutrition inputs were fitted using Intensive Control Insulin Nutrition Glucose (ICING) model to generate the insulin sensitivity numerically by iterative-integral method. The 95% of confidence interval and Kolmogorov-Smirnov test (p<0.05) were used to evaluate the performance of protocol between the Stochastic TARgeted (STAR) and HTAA protocols per cohorts and per patients. Results indicates BG median [with IQR] recorded in STAR protocol for the whole cohort statistics is lower than HTAA Protocol where 7.4 mmol/L [5.7-9.4] and 8.6 mmol/L [6.8-10.9] respectively. STAR is successful in lowering the BGL which can be seen from the % BG > 10.0 mmol/L is 19.7% while 32.8% for HTAA Protocol. The drawback from this positive result is the increment of hypoglycaemic patients (HTAA Protocol: 9; STAR: 36). Thus, STAR is the best solution in controlling the patients’ BG level especially in Malaysian cohort but the enhancement of STAR have to be done to prevent the risk of hypoglycaemia by introducing patient-specific nutrition controller that can be combined with insulin infusion. Institute of Electrical and Electronics Engineers Inc. 2016-10-22 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/56708/1/56708_I2CACIS.pdf application/pdf en http://irep.iium.edu.my/56708/2/56708_I2CACIS_SCOPUS.pdf Humaidi, M. Luqman and WM Zulkifly, W Zuhriraihan and Rosly, C. Zafirah and Khalid, Khalijah and Jamaludin, Ummu Kulthum and Md Ralib, Azrina and Mat Nor, Mohd. Basri (2016) Performance of blood glucose management protocols in HTAA intensive care unit. In: 2016 IEEE International Conference on Automatic Control and Intelligent Systems (I2CACIS),, 22 October 2016, Shah Alam. http://ieeexplore.ieee.org/xpl/mostRecentIssue.jsp?punumber=7878325 10.1109/I2CACIS.2016.7885307
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic R Medicine (General)
spellingShingle R Medicine (General)
Humaidi, M. Luqman
WM Zulkifly, W Zuhriraihan
Rosly, C. Zafirah
Khalid, Khalijah
Jamaludin, Ummu Kulthum
Md Ralib, Azrina
Mat Nor, Mohd. Basri
Performance of blood glucose management protocols in HTAA intensive care unit
description Abstract—Insulin Infusion Therapy (IIT) has been implemented in Malaysia Intensive Care Unit (ICU) for decades to control blood glucose level (BGL) among critically ill patients. In this study, clinical data of 210 patients treated with IIT-HTAA protocol and the minimum length of stay of 1 day were analysed. BGL, insulin and nutrition inputs were fitted using Intensive Control Insulin Nutrition Glucose (ICING) model to generate the insulin sensitivity numerically by iterative-integral method. The 95% of confidence interval and Kolmogorov-Smirnov test (p<0.05) were used to evaluate the performance of protocol between the Stochastic TARgeted (STAR) and HTAA protocols per cohorts and per patients. Results indicates BG median [with IQR] recorded in STAR protocol for the whole cohort statistics is lower than HTAA Protocol where 7.4 mmol/L [5.7-9.4] and 8.6 mmol/L [6.8-10.9] respectively. STAR is successful in lowering the BGL which can be seen from the % BG > 10.0 mmol/L is 19.7% while 32.8% for HTAA Protocol. The drawback from this positive result is the increment of hypoglycaemic patients (HTAA Protocol: 9; STAR: 36). Thus, STAR is the best solution in controlling the patients’ BG level especially in Malaysian cohort but the enhancement of STAR have to be done to prevent the risk of hypoglycaemia by introducing patient-specific nutrition controller that can be combined with insulin infusion.
format Conference or Workshop Item
author Humaidi, M. Luqman
WM Zulkifly, W Zuhriraihan
Rosly, C. Zafirah
Khalid, Khalijah
Jamaludin, Ummu Kulthum
Md Ralib, Azrina
Mat Nor, Mohd. Basri
author_facet Humaidi, M. Luqman
WM Zulkifly, W Zuhriraihan
Rosly, C. Zafirah
Khalid, Khalijah
Jamaludin, Ummu Kulthum
Md Ralib, Azrina
Mat Nor, Mohd. Basri
author_sort Humaidi, M. Luqman
title Performance of blood glucose management protocols in HTAA intensive care unit
title_short Performance of blood glucose management protocols in HTAA intensive care unit
title_full Performance of blood glucose management protocols in HTAA intensive care unit
title_fullStr Performance of blood glucose management protocols in HTAA intensive care unit
title_full_unstemmed Performance of blood glucose management protocols in HTAA intensive care unit
title_sort performance of blood glucose management protocols in htaa intensive care unit
publisher Institute of Electrical and Electronics Engineers Inc.
publishDate 2016
url http://irep.iium.edu.my/56708/
http://irep.iium.edu.my/56708/
http://irep.iium.edu.my/56708/
http://irep.iium.edu.my/56708/1/56708_I2CACIS.pdf
http://irep.iium.edu.my/56708/2/56708_I2CACIS_SCOPUS.pdf
first_indexed 2023-09-18T21:20:03Z
last_indexed 2023-09-18T21:20:03Z
_version_ 1777411821531037696