In vitro antioxidant, antityrosinase, antibacterial and cytotoxicity activities of the leaf and stem essential oil from piper magnibaccum C. DC.

The chemical composition of essential oils obtained from two parts of Piper magnibaccum C.DC. were analyzed by gas chromatography with a flame ionization detector (GC- FID) and gas chromatography- mass spectrometry (GC- MS). 25 components representing 93.5 % of the essential oil were characterized f...

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Main Authors:	Hashim, Nur Athirah, Ahmad, Farediah, Jani, Nor Akmalazura, Darnis, Deny Susanti
Format:	Article
Language:	English English English
Published:	Taylor and Francis 2017
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/56457/ http://irep.iium.edu.my/56457/ http://irep.iium.edu.my/56457/ http://irep.iium.edu.my/56457/1/J.%20Essential%20oil%20Bearing%20Plants.pdf http://irep.iium.edu.my/56457/7/56457-In%20vitro%20Antioxidant%2C%20Antityrosinase%2C%20Antibacterial_SCOPUS.pdf http://irep.iium.edu.my/56457/8/56457-In%20vitro%20Antioxidant%2C%20Antityrosinase%2C%20Antibacterial_WOS.pdf

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recordtype	eprints
spelling	iium-564572017-07-18T01:02:56Z http://irep.iium.edu.my/56457/ In vitro antioxidant, antityrosinase, antibacterial and cytotoxicity activities of the leaf and stem essential oil from piper magnibaccum C. DC. Hashim, Nur Athirah Ahmad, Farediah Jani, Nor Akmalazura Darnis, Deny Susanti QD Chemistry The chemical composition of essential oils obtained from two parts of Piper magnibaccum C.DC. were analyzed by gas chromatography with a flame ionization detector (GC- FID) and gas chromatography- mass spectrometry (GC- MS). 25 components representing 93.5 % of the essential oil were characterized from the leaf of P. magnibaccum. The essential oil was dominated by germacrene D (40.8 %), β-caryophyllene (8.5 %) and α-cadinol (6.1 %). A total of 33 components, representing 87.6 % of the total oil were identified from the stem of P. magnibaccum. The major constituents were β-caryophyllene (19.7 %), germacrene D (10.7 %), and α- cadinol (8.2 %). The antioxidant potential of the leaf and stem essential oils of P. magnibaccum were determined on the basis of phenolic content and scavenging activity of the stable 1,1-diphenyl-2-picrylhydrazyl (DPPH) (IC50 20.5, 17.5 μg/mL) and 2,2’-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) (IC50 11.7, 12.9 μg/ mL) free radicals. Antityrosinase activity of the leaf and stem were also screened using mushroom tyrosinase assay (I %= 49.50±0.6, 57.01±0.8). The essential oil of P. magnibaccum leaf showed a moderate antibacterial activity with MIC value of 250 μg/mL against P. aeruginosa. None of the essential oils exhibited acute cytotoxicity against MCF-7 and A-549 cells proliferation. Taylor and Francis 2017 Article PeerReviewed application/pdf en http://irep.iium.edu.my/56457/1/J.%20Essential%20oil%20Bearing%20Plants.pdf application/pdf en http://irep.iium.edu.my/56457/7/56457-In%20vitro%20Antioxidant%2C%20Antityrosinase%2C%20Antibacterial_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/56457/8/56457-In%20vitro%20Antioxidant%2C%20Antityrosinase%2C%20Antibacterial_WOS.pdf Hashim, Nur Athirah and Ahmad, Farediah and Jani, Nor Akmalazura and Darnis, Deny Susanti (2017) In vitro antioxidant, antityrosinase, antibacterial and cytotoxicity activities of the leaf and stem essential oil from piper magnibaccum C. DC. Journal of Essential Oil Bearing Plants, 20 (1). pp. 223-232. ISSN 0972-060X E-ISSN 0976-5026 http://www.tandfonline.com/doi/abs/10.1080/0972060X.2017.1282839 10.1080/0972060X.2017.1282839
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	QD Chemistry
spellingShingle	QD Chemistry Hashim, Nur Athirah Ahmad, Farediah Jani, Nor Akmalazura Darnis, Deny Susanti In vitro antioxidant, antityrosinase, antibacterial and cytotoxicity activities of the leaf and stem essential oil from piper magnibaccum C. DC.
description	The chemical composition of essential oils obtained from two parts of Piper magnibaccum C.DC. were analyzed by gas chromatography with a flame ionization detector (GC- FID) and gas chromatography- mass spectrometry (GC- MS). 25 components representing 93.5 % of the essential oil were characterized from the leaf of P. magnibaccum. The essential oil was dominated by germacrene D (40.8 %), β-caryophyllene (8.5 %) and α-cadinol (6.1 %). A total of 33 components, representing 87.6 % of the total oil were identified from the stem of P. magnibaccum. The major constituents were β-caryophyllene (19.7 %), germacrene D (10.7 %), and α- cadinol (8.2 %). The antioxidant potential of the leaf and stem essential oils of P. magnibaccum were determined on the basis of phenolic content and scavenging activity of the stable 1,1-diphenyl-2-picrylhydrazyl (DPPH) (IC50 20.5, 17.5 μg/mL) and 2,2’-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) (IC50 11.7, 12.9 μg/ mL) free radicals. Antityrosinase activity of the leaf and stem were also screened using mushroom tyrosinase assay (I %= 49.50±0.6, 57.01±0.8). The essential oil of P. magnibaccum leaf showed a moderate antibacterial activity with MIC value of 250 μg/mL against P. aeruginosa. None of the essential oils exhibited acute cytotoxicity against MCF-7 and A-549 cells proliferation.
format	Article
author	Hashim, Nur Athirah Ahmad, Farediah Jani, Nor Akmalazura Darnis, Deny Susanti
author_facet	Hashim, Nur Athirah Ahmad, Farediah Jani, Nor Akmalazura Darnis, Deny Susanti
author_sort	Hashim, Nur Athirah
title	In vitro antioxidant, antityrosinase, antibacterial and cytotoxicity activities of the leaf and stem essential oil from piper magnibaccum C. DC.
title_short	In vitro antioxidant, antityrosinase, antibacterial and cytotoxicity activities of the leaf and stem essential oil from piper magnibaccum C. DC.
title_full	In vitro antioxidant, antityrosinase, antibacterial and cytotoxicity activities of the leaf and stem essential oil from piper magnibaccum C. DC.
title_fullStr	In vitro antioxidant, antityrosinase, antibacterial and cytotoxicity activities of the leaf and stem essential oil from piper magnibaccum C. DC.
title_full_unstemmed	In vitro antioxidant, antityrosinase, antibacterial and cytotoxicity activities of the leaf and stem essential oil from piper magnibaccum C. DC.
title_sort	in vitro antioxidant, antityrosinase, antibacterial and cytotoxicity activities of the leaf and stem essential oil from piper magnibaccum c. dc.
publisher	Taylor and Francis
publishDate	2017
url	http://irep.iium.edu.my/56457/ http://irep.iium.edu.my/56457/ http://irep.iium.edu.my/56457/ http://irep.iium.edu.my/56457/1/J.%20Essential%20oil%20Bearing%20Plants.pdf http://irep.iium.edu.my/56457/7/56457-In%20vitro%20Antioxidant%2C%20Antityrosinase%2C%20Antibacterial_SCOPUS.pdf http://irep.iium.edu.my/56457/8/56457-In%20vitro%20Antioxidant%2C%20Antityrosinase%2C%20Antibacterial_WOS.pdf
first_indexed	2023-09-18T21:19:40Z
last_indexed	2023-09-18T21:19:40Z
_version_	1777411796743749632

In vitro antioxidant, antityrosinase, antibacterial and cytotoxicity activities of the leaf and stem essential oil from piper magnibaccum C. DC.

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