Live birth rates are satisfactory following multiple IVF treatment cycles in poor prognosis patients

This seven-year retrospective study analysed the live birth rate (LBR) for women undergoing IVF treatment with various antral follicle counts (AFC). The LBR decreased with lower AFC ratings, and in 290 treatment cycles for women in the poorest AFC category, �4 follicles (group E), the LBR was the...

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Main Authors:	Mustafa, Kamarul Bahyah, Keane, Kevin Noel, Walz, Nikita L., Mitrovic, Katarina I., Hinchliffe, Peter M., Yovich, John L.
Format:	Article
Language:	English English English
Published:	Elsevier 2017
Subjects:	RG Gynecology and obstetrics
Online Access:	http://irep.iium.edu.my/56322/ http://irep.iium.edu.my/56322/ http://irep.iium.edu.my/56322/1/live%20birth%20rates-%20Dr%20kamarulbahyah.pdf http://irep.iium.edu.my/56322/7/56322-Live%20birth%20rates%20are%20satisfactory%20following%20multiple%20IVF%20treatment%20cycles%20_SCOPUS.pdf http://irep.iium.edu.my/56322/8/56322-Live%20birth%20rates%20are%20satisfactory%20following%20multiple%20IVF%20treatment%20cycles%20_WOS.pdf

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spelling	iium-563222017-08-16T03:11:55Z http://irep.iium.edu.my/56322/ Live birth rates are satisfactory following multiple IVF treatment cycles in poor prognosis patients Mustafa, Kamarul Bahyah Keane, Kevin Noel Walz, Nikita L. Mitrovic, Katarina I. Hinchliffe, Peter M. Yovich, John L. RG Gynecology and obstetrics This seven-year retrospective study analysed the live birth rate (LBR) for women undergoing IVF treatment with various antral follicle counts (AFC). The LBR decreased with lower AFC ratings, and in 290 treatment cycles for women in the poorest AFC category, �4 follicles (group E), the LBR was the lowest at 10.7%. The pregnancy loss rate (PLR) significantly increased with poorer AFC categories, from 21.8% in AFC group A (20 follicles), to 54.4% in AFC group E (p < 0.0001). This trend was repeated with advancing age, from 21.6% for younger women ( < 35 years), to 32.9, 48.5 and 100% for ages 35–39, 40–44 and 45 years, respectively (p < 0.0001). However, LBR within the specific AFC group E cohort was also age-dependent and decreased significantly from 30.0% for <35 years old, to 13.3, 3.9 and 0% for patients aged 35–39, 40– 44 and 45 years, respectively. Most, importantly, LBR rates within these age groups were not dependent on the number of IVF attempts (1st, 2nd, 3rd or 4 cycles), which indicated that cycle number should not be the primary deciding factor for cessation of IVF treatment in responding women <45years old. Elsevier 2017-03 Article PeerReviewed application/pdf en http://irep.iium.edu.my/56322/1/live%20birth%20rates-%20Dr%20kamarulbahyah.pdf application/pdf en http://irep.iium.edu.my/56322/7/56322-Live%20birth%20rates%20are%20satisfactory%20following%20multiple%20IVF%20treatment%20cycles%20_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/56322/8/56322-Live%20birth%20rates%20are%20satisfactory%20following%20multiple%20IVF%20treatment%20cycles%20_WOS.pdf Mustafa, Kamarul Bahyah and Keane, Kevin Noel and Walz, Nikita L. and Mitrovic, Katarina I. and Hinchliffe, Peter M. and Yovich, John L. (2017) Live birth rates are satisfactory following multiple IVF treatment cycles in poor prognosis patients. Reproductive Biology, 17 (1). pp. 34-41. ISSN 1642-431X http://www.sciencedirect.com/science/article/pii/S1642431X16300730
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	RG Gynecology and obstetrics
spellingShingle	RG Gynecology and obstetrics Mustafa, Kamarul Bahyah Keane, Kevin Noel Walz, Nikita L. Mitrovic, Katarina I. Hinchliffe, Peter M. Yovich, John L. Live birth rates are satisfactory following multiple IVF treatment cycles in poor prognosis patients
description	This seven-year retrospective study analysed the live birth rate (LBR) for women undergoing IVF treatment with various antral follicle counts (AFC). The LBR decreased with lower AFC ratings, and in 290 treatment cycles for women in the poorest AFC category, �4 follicles (group E), the LBR was the lowest at 10.7%. The pregnancy loss rate (PLR) significantly increased with poorer AFC categories, from 21.8% in AFC group A (20 follicles), to 54.4% in AFC group E (p < 0.0001). This trend was repeated with advancing age, from 21.6% for younger women ( < 35 years), to 32.9, 48.5 and 100% for ages 35–39, 40–44 and 45 years, respectively (p < 0.0001). However, LBR within the specific AFC group E cohort was also age-dependent and decreased significantly from 30.0% for <35 years old, to 13.3, 3.9 and 0% for patients aged 35–39, 40– 44 and 45 years, respectively. Most, importantly, LBR rates within these age groups were not dependent on the number of IVF attempts (1st, 2nd, 3rd or 4 cycles), which indicated that cycle number should not be the primary deciding factor for cessation of IVF treatment in responding women <45years old.
format	Article
author	Mustafa, Kamarul Bahyah Keane, Kevin Noel Walz, Nikita L. Mitrovic, Katarina I. Hinchliffe, Peter M. Yovich, John L.
author_facet	Mustafa, Kamarul Bahyah Keane, Kevin Noel Walz, Nikita L. Mitrovic, Katarina I. Hinchliffe, Peter M. Yovich, John L.
author_sort	Mustafa, Kamarul Bahyah
title	Live birth rates are satisfactory following multiple IVF treatment cycles in poor prognosis patients
title_short	Live birth rates are satisfactory following multiple IVF treatment cycles in poor prognosis patients
title_full	Live birth rates are satisfactory following multiple IVF treatment cycles in poor prognosis patients
title_fullStr	Live birth rates are satisfactory following multiple IVF treatment cycles in poor prognosis patients
title_full_unstemmed	Live birth rates are satisfactory following multiple IVF treatment cycles in poor prognosis patients
title_sort	live birth rates are satisfactory following multiple ivf treatment cycles in poor prognosis patients
publisher	Elsevier
publishDate	2017
url	http://irep.iium.edu.my/56322/ http://irep.iium.edu.my/56322/ http://irep.iium.edu.my/56322/1/live%20birth%20rates-%20Dr%20kamarulbahyah.pdf http://irep.iium.edu.my/56322/7/56322-Live%20birth%20rates%20are%20satisfactory%20following%20multiple%20IVF%20treatment%20cycles%20_SCOPUS.pdf http://irep.iium.edu.my/56322/8/56322-Live%20birth%20rates%20are%20satisfactory%20following%20multiple%20IVF%20treatment%20cycles%20_WOS.pdf
first_indexed	2023-09-18T21:19:26Z
last_indexed	2023-09-18T21:19:26Z
_version_	1777411782787203072

Live birth rates are satisfactory following multiple IVF treatment cycles in poor prognosis patients

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