Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum

Gliclazide(1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4- methylphenyl) sulfonylurea) is a second-generation sulfonylurea which is orally administered in the treatment of non-insulin-dependent diabetes mellitus in adults. Sustain release drugs help to improve drugs bioava...

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Main Authors:	Mat Zin, Nik Mohamad Lukman, Abd Mubin, Anis Syazwani, Mohd. Nawi, Mohamed Sufian, Helaluddin, Abul Bashar Mohammed, Kasmuri, Abdul Razak, Mandal, Uttam Kumar
Format:	Conference or Workshop Item
Language:	English
Published:	2016
Subjects:	QD Chemistry R Medicine (General) RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/55426/ http://irep.iium.edu.my/55426/ http://irep.iium.edu.my/55426/2/55426.pdf

id	iium-55426
recordtype	eprints
spelling	iium-554262018-11-28T03:35:15Z http://irep.iium.edu.my/55426/ Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum Mat Zin, Nik Mohamad Lukman Abd Mubin, Anis Syazwani, Mohd. Nawi, Mohamed Sufian Helaluddin, Abul Bashar Mohammed Kasmuri, Abdul Razak Mandal, Uttam Kumar QD Chemistry R Medicine (General) RS Pharmacy and materia medica Gliclazide(1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4- methylphenyl) sulfonylurea) is a second-generation sulfonylurea which is orally administered in the treatment of non-insulin-dependent diabetes mellitus in adults. Sustain release drugs help to improve drugs bioavailability by controlling the time of drug release or prolonging it. We are reporting the preliminary formulation of sustain release gliclazide tablets with careful choice of all the ingredients and processes related to syariah compliance manufacturing of pharmaceutical products. In this work, xanthan gum, a natural gum was used to achieve the sustain release criteria. The tablets were produced by wet granulation and semi-automatic tableting process. Tablet characterisation was done following the British Pharmacopoeia (BP) criteria. We expect that the outcome of our study will result in a suitable formulation that could be useful for the formulation of such product that will be helpful for the Muslim patient especially during the fasting month. 2016 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/55426/2/55426.pdf Mat Zin, Nik Mohamad Lukman and Abd Mubin, Anis Syazwani, and Mohd. Nawi, Mohamed Sufian and Helaluddin, Abul Bashar Mohammed and Kasmuri, Abdul Razak and Mandal, Uttam Kumar (2016) Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum. In: 2nd World Congress on Integration and Islamicisation: Focus on Medical and Healthcare Science (2WCII 2016), 21st-23rd October 2016, Kuantan, Pahang. (Unpublished) http://www.iium.edu.my/centris/events/2nd-world-congress-integration-islamicisation-focus-medical-health-care-sciences-2016
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry R Medicine (General) RS Pharmacy and materia medica
spellingShingle	QD Chemistry R Medicine (General) RS Pharmacy and materia medica Mat Zin, Nik Mohamad Lukman Abd Mubin, Anis Syazwani, Mohd. Nawi, Mohamed Sufian Helaluddin, Abul Bashar Mohammed Kasmuri, Abdul Razak Mandal, Uttam Kumar Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum
description	Gliclazide(1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4- methylphenyl) sulfonylurea) is a second-generation sulfonylurea which is orally administered in the treatment of non-insulin-dependent diabetes mellitus in adults. Sustain release drugs help to improve drugs bioavailability by controlling the time of drug release or prolonging it. We are reporting the preliminary formulation of sustain release gliclazide tablets with careful choice of all the ingredients and processes related to syariah compliance manufacturing of pharmaceutical products. In this work, xanthan gum, a natural gum was used to achieve the sustain release criteria. The tablets were produced by wet granulation and semi-automatic tableting process. Tablet characterisation was done following the British Pharmacopoeia (BP) criteria. We expect that the outcome of our study will result in a suitable formulation that could be useful for the formulation of such product that will be helpful for the Muslim patient especially during the fasting month.
format	Conference or Workshop Item
author	Mat Zin, Nik Mohamad Lukman Abd Mubin, Anis Syazwani, Mohd. Nawi, Mohamed Sufian Helaluddin, Abul Bashar Mohammed Kasmuri, Abdul Razak Mandal, Uttam Kumar
author_facet	Mat Zin, Nik Mohamad Lukman Abd Mubin, Anis Syazwani, Mohd. Nawi, Mohamed Sufian Helaluddin, Abul Bashar Mohammed Kasmuri, Abdul Razak Mandal, Uttam Kumar
author_sort	Mat Zin, Nik Mohamad Lukman
title	Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum
title_short	Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum
title_full	Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum
title_fullStr	Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum
title_full_unstemmed	Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum
title_sort	preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum
publishDate	2016
url	http://irep.iium.edu.my/55426/ http://irep.iium.edu.my/55426/ http://irep.iium.edu.my/55426/2/55426.pdf
first_indexed	2023-09-18T21:18:21Z
last_indexed	2023-09-18T21:18:21Z
_version_	1777411713678704640

Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum

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