Transforming growth factor-β signalling: role and consequences of Smad linker region phosphorylation
Transforming growth factor-β (TGF-β) is a secreted homodimeric protein that plays an important role in regulating various cellular responses including cell proliferation and differentiation, extracellular matrix production, embryonic development and apoptosis. Disruption of the TGF-β signalling path...
Main Authors: | Kamato, Danielle, Burch, Micah L., Piva, Terence J., Rezaei, Hossein B., Rostam, Muhamad Ashraf, Xu, Suowen, Zheng, Wenhua, Little, Peter J., Osman, Narin |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2013
|
Subjects: | |
Online Access: | http://irep.iium.edu.my/55278/ http://irep.iium.edu.my/55278/ http://irep.iium.edu.my/55278/ http://irep.iium.edu.my/55278/8/6.%20Kamato-2013-Transforming%20growth%20factor-%CE%B2%20signa.pdf |
Similar Items
-
The role of specific Smad linker region phosphorylation in TGF-β
mediated expression of glycosaminoglycan synthesizing
enzymes in vascular smooth muscle
by: Rostam, Muhamad Ashraf, et al.
Published: (2016) -
Transforming growth factor β-mediated site-specific Smad
linker region phosphorylation in vascular endothelial cells
by: Kamato, Danielle, et al.
Published: (2014) -
Flavopiridol inhibits TGF-β-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2
by: Rostam, Muhamad Ashraf, et al.
Published: (2018) -
Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and
glycosaminoglycan hyperelongation in human vascular smooth muscle cells
by: Little, Peter J., et al.
Published: (2013) -
Peptidyl-prolyl isomerases: Functionality and potential therapeutic targets in cardiovascular disease
by: Rostam, Muhamad Ashraf, et al.
Published: (2015)