Porous hydroxyapatite for artificial bone applications

Hydroxyapatite (HA) has been used clinically for many years. It has good biocompatibility in bone contact as its chemical composition is similar to that of bone material. Porous HA ceramics have found enormous use in biomedical applications including bone tissue regeneration, cell proliferation, and...

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Main Authors: Iis, Sopyan, Mel, Maizirwan, Singh, Ramesh, Khalid, Kamarul Ariffin
Format: Article
Language:English
Published: Elsevier 2007
Subjects:
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spelling iium-54772015-09-14T04:21:55Z http://irep.iium.edu.my/5477/ Porous hydroxyapatite for artificial bone applications Iis, Sopyan Mel, Maizirwan Singh, Ramesh Khalid, Kamarul Ariffin TP155 Chemical engineering TP248.13 Biotechnology Hydroxyapatite (HA) has been used clinically for many years. It has good biocompatibility in bone contact as its chemical composition is similar to that of bone material. Porous HA ceramics have found enormous use in biomedical applications including bone tissue regeneration, cell proliferation, and drug delivery. In bone tissue engineering it has been applied as filling material for bone defects and augmentation, artificial bone graft material, and prosthesis revision surgery. Its high surface area leads to excellent osteoconductivity and resorbability providing fast bone ingrowth. Porous HA can be produced by a number of methods including conversion of natural bones, ceramic foaming technique, polymeric sponge method, gel casting of foams, starch consolidation, microwave processing, slip casting, and electrophoretic deposition technique. Some of these methods have been combined to fabricate porous HA with improved properties. These combination methods have yielded some promising results. This paper discusses briefly fundamental aspects of porous HA for artificial bone applications as well as various techniques used to prepare porous HA. Some of our recent results on development ofmporous HA will be presented as well. Elsevier 2007 Article PeerReviewed application/pdf en http://irep.iium.edu.my/5477/1/STAM_porous_HA-Published.pdf Iis, Sopyan and Mel, Maizirwan and Singh, Ramesh and Khalid, Kamarul Ariffin (2007) Porous hydroxyapatite for artificial bone applications. Science and Technology of Advanced Materials, 8 (1-2). pp. 116-123. ISSN 1468-6996 http://www.sciencedirect.com 10.1016/j.stam.2006.11.017
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic TP155 Chemical engineering
TP248.13 Biotechnology
spellingShingle TP155 Chemical engineering
TP248.13 Biotechnology
Iis, Sopyan
Mel, Maizirwan
Singh, Ramesh
Khalid, Kamarul Ariffin
Porous hydroxyapatite for artificial bone applications
description Hydroxyapatite (HA) has been used clinically for many years. It has good biocompatibility in bone contact as its chemical composition is similar to that of bone material. Porous HA ceramics have found enormous use in biomedical applications including bone tissue regeneration, cell proliferation, and drug delivery. In bone tissue engineering it has been applied as filling material for bone defects and augmentation, artificial bone graft material, and prosthesis revision surgery. Its high surface area leads to excellent osteoconductivity and resorbability providing fast bone ingrowth. Porous HA can be produced by a number of methods including conversion of natural bones, ceramic foaming technique, polymeric sponge method, gel casting of foams, starch consolidation, microwave processing, slip casting, and electrophoretic deposition technique. Some of these methods have been combined to fabricate porous HA with improved properties. These combination methods have yielded some promising results. This paper discusses briefly fundamental aspects of porous HA for artificial bone applications as well as various techniques used to prepare porous HA. Some of our recent results on development ofmporous HA will be presented as well.
format Article
author Iis, Sopyan
Mel, Maizirwan
Singh, Ramesh
Khalid, Kamarul Ariffin
author_facet Iis, Sopyan
Mel, Maizirwan
Singh, Ramesh
Khalid, Kamarul Ariffin
author_sort Iis, Sopyan
title Porous hydroxyapatite for artificial bone applications
title_short Porous hydroxyapatite for artificial bone applications
title_full Porous hydroxyapatite for artificial bone applications
title_fullStr Porous hydroxyapatite for artificial bone applications
title_full_unstemmed Porous hydroxyapatite for artificial bone applications
title_sort porous hydroxyapatite for artificial bone applications
publisher Elsevier
publishDate 2007
url http://irep.iium.edu.my/5477/
http://irep.iium.edu.my/5477/
http://irep.iium.edu.my/5477/
http://irep.iium.edu.my/5477/1/STAM_porous_HA-Published.pdf
first_indexed 2023-09-18T20:14:06Z
last_indexed 2023-09-18T20:14:06Z
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