Recent update on nanoemulgel as topical drug delivery system

Being an emerging transdermal delivery tool, nanoemulgel, has proved to show surprising upshots for the lipophilic drugs over other formulations. This lipophilic nature of majority of the newer drugs developed in this modern era resulting in poor oral bioavailability, erratic absorption, and pharmac...

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Main Authors:	Choudhury, Hira, Gorain, Bapi, Pandey, Manisha, Chatterjee, Lipika Alok, Sengupta, Pinaki, Das, Arindam, Molugulu, Nagashekhara, Kesharwani, Prashant
Format:	Article
Language:	English English
Published:	John Wiley and Sons 2017
Subjects:	RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/54448/ http://irep.iium.edu.my/54448/ http://irep.iium.edu.my/54448/2/54448_Recent%20Update%20on%20Nanoemulgel_SCOPUS.pdf http://irep.iium.edu.my/54448/3/54448_Recent%20update%20on%20nanoemulgel.pdf

id	iium-54448
recordtype	eprints
spelling	iium-544482018-01-05T08:26:27Z http://irep.iium.edu.my/54448/ Recent update on nanoemulgel as topical drug delivery system Choudhury, Hira Gorain, Bapi Pandey, Manisha Chatterjee, Lipika Alok Sengupta, Pinaki Das, Arindam Molugulu, Nagashekhara Kesharwani, Prashant RS Pharmacy and materia medica Being an emerging transdermal delivery tool, nanoemulgel, has proved to show surprising upshots for the lipophilic drugs over other formulations. This lipophilic nature of majority of the newer drugs developed in this modern era resulting in poor oral bioavailability, erratic absorption, and pharmacokinetic variations. Therefore, this novel transdermal delivery system has been proved to be advantageous over other oral and topical drug delivery to avoid such disturbances. These nanoemulgels are basically oil-in-water nanoemulsions gelled with the use of some gelling agent in it. This gel phase in the formulation is nongreasy, which favors user compliance and stabilizes the formulation through reduction in surface as well as interfacial tension. Simultaneously, it can be targeted more specifically to the site of action and can avoid first-pass metabolism and relieve the user from gastric/systemic incompatibilities. This brief review is focused on nanoemulgel as a better topical drug delivery system including its components screening, formulation method, and recent pharmacokinetic and pharmacodynamic advancement in research studies carried out by the scientists all over the world. Therefore, at the end of this survey it could be inferred that nanoemulgel can be a better and effective drug delivery tool for the topical system. John Wiley and Sons 2017-07-17 Article PeerReviewed application/pdf en http://irep.iium.edu.my/54448/2/54448_Recent%20Update%20on%20Nanoemulgel_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/54448/3/54448_Recent%20update%20on%20nanoemulgel.pdf Choudhury, Hira and Gorain, Bapi and Pandey, Manisha and Chatterjee, Lipika Alok and Sengupta, Pinaki and Das, Arindam and Molugulu, Nagashekhara and Kesharwani, Prashant (2017) Recent update on nanoemulgel as topical drug delivery system. Journal of Pharmaceutical Sciences, 106 (7). pp. 1736-1751. ISSN 0022-3549 http://www.sciencedirect.com/journal/journal-of-pharmaceutical-sciences
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RS Pharmacy and materia medica
spellingShingle	RS Pharmacy and materia medica Choudhury, Hira Gorain, Bapi Pandey, Manisha Chatterjee, Lipika Alok Sengupta, Pinaki Das, Arindam Molugulu, Nagashekhara Kesharwani, Prashant Recent update on nanoemulgel as topical drug delivery system
description	Being an emerging transdermal delivery tool, nanoemulgel, has proved to show surprising upshots for the lipophilic drugs over other formulations. This lipophilic nature of majority of the newer drugs developed in this modern era resulting in poor oral bioavailability, erratic absorption, and pharmacokinetic variations. Therefore, this novel transdermal delivery system has been proved to be advantageous over other oral and topical drug delivery to avoid such disturbances. These nanoemulgels are basically oil-in-water nanoemulsions gelled with the use of some gelling agent in it. This gel phase in the formulation is nongreasy, which favors user compliance and stabilizes the formulation through reduction in surface as well as interfacial tension. Simultaneously, it can be targeted more specifically to the site of action and can avoid first-pass metabolism and relieve the user from gastric/systemic incompatibilities. This brief review is focused on nanoemulgel as a better topical drug delivery system including its components screening, formulation method, and recent pharmacokinetic and pharmacodynamic advancement in research studies carried out by the scientists all over the world. Therefore, at the end of this survey it could be inferred that nanoemulgel can be a better and effective drug delivery tool for the topical system.
format	Article
author	Choudhury, Hira Gorain, Bapi Pandey, Manisha Chatterjee, Lipika Alok Sengupta, Pinaki Das, Arindam Molugulu, Nagashekhara Kesharwani, Prashant
author_facet	Choudhury, Hira Gorain, Bapi Pandey, Manisha Chatterjee, Lipika Alok Sengupta, Pinaki Das, Arindam Molugulu, Nagashekhara Kesharwani, Prashant
author_sort	Choudhury, Hira
title	Recent update on nanoemulgel as topical drug delivery system
title_short	Recent update on nanoemulgel as topical drug delivery system
title_full	Recent update on nanoemulgel as topical drug delivery system
title_fullStr	Recent update on nanoemulgel as topical drug delivery system
title_full_unstemmed	Recent update on nanoemulgel as topical drug delivery system
title_sort	recent update on nanoemulgel as topical drug delivery system
publisher	John Wiley and Sons
publishDate	2017
url	http://irep.iium.edu.my/54448/ http://irep.iium.edu.my/54448/ http://irep.iium.edu.my/54448/2/54448_Recent%20Update%20on%20Nanoemulgel_SCOPUS.pdf http://irep.iium.edu.my/54448/3/54448_Recent%20update%20on%20nanoemulgel.pdf
first_indexed	2023-09-18T21:17:04Z
last_indexed	2023-09-18T21:17:04Z
_version_	1777411633020141568

Recent update on nanoemulgel as topical drug delivery system

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