Potential of untapped local species, “Chicha” (Stereospermum fimbriatum), as an alternative for skin infection treatment

Skin infection diseases are among the most common skin problems. Scientists believe that plants play a vital role in the public health. Stereospermum fimbriatum or “Chicha” used traditionally to cure stomachache, earache, itchy skin and postpartum illness. Therefore, this study was designed to inves...

Full description

Bibliographic Details
Main Authors:	Awang, Anis Fadhlina Izyani, Sarker, Md. Zaidul Islam, Ahmed, Qamar Uddin, Md. Jaffri, Juliana, Omar, Muhammad Nor
Format:	Conference or Workshop Item
Language:	English
Published:	Fakulti Sains dan Teknologi, Universiti Kebangsaan Malaysia, 2016
Subjects:	TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/54094/ http://irep.iium.edu.my/54094/ http://irep.iium.edu.my/54094/1/54094_Potential%20of%20untapped%20local%20species.pdf

id	iium-54094
recordtype	eprints
spelling	iium-540942019-10-14T01:53:41Z http://irep.iium.edu.my/54094/ Potential of untapped local species, “Chicha” (Stereospermum fimbriatum), as an alternative for skin infection treatment Awang, Anis Fadhlina Izyani Sarker, Md. Zaidul Islam Ahmed, Qamar Uddin Md. Jaffri, Juliana Omar, Muhammad Nor TP248.13 Biotechnology Skin infection diseases are among the most common skin problems. Scientists believe that plants play a vital role in the public health. Stereospermum fimbriatum or “Chicha” used traditionally to cure stomachache, earache, itchy skin and postpartum illness. Therefore, this study was designed to investigate the phytochemical constituents of flowers, leaves, stem bark and twig of S. fimbriatum and their antimicrobial potential against eleven skin pathogens. Successive soxhlet extraction by n-hexane, dichloromethane and methanol was used. Disc diffusion, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were done to investigate their antimicrobial activities. Presence of terpenoid, steroid, flavonoid, saponin and tannin were observed in certain plant’s parts only. n-hexane extract of the S. fimbriatum’s stem bark (NS) possessed the most potent antibacterial activity especially against Staphylococcus epidermidis (16 mm±1), followed by MRSA (13.67 mm±0.58) and S. aureus (11.33 mm±0.58). All extracts exhibited no antimicrobial activity against Escherichia coli, Bacillus cereus, Pseudomonas aeruginosa, Proteus vulgaris, Enterococcus aerogenes, Candida albicans and Microsporum gypseum, except NS against S. pyogenes with weak antibacterial activity. The MIC analysis of susceptible strains resulted with a value of 1000 μg/mL. This study might lead to the discovery of novel agents with potential to treat dermal infections. Fakulti Sains dan Teknologi, Universiti Kebangsaan Malaysia, 2016 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/54094/1/54094_Potential%20of%20untapped%20local%20species.pdf Awang, Anis Fadhlina Izyani and Sarker, Md. Zaidul Islam and Ahmed, Qamar Uddin and Md. Jaffri, Juliana and Omar, Muhammad Nor (2016) Potential of untapped local species, “Chicha” (Stereospermum fimbriatum), as an alternative for skin infection treatment. In: The 14th Symposium of Malaysian Society of Applied Biology (MSAB 2016), 29th–31st May 2016, Melaka. http://msabsimposium.blogspot.my/p/poster-presentation.html
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	TP248.13 Biotechnology
spellingShingle	TP248.13 Biotechnology Awang, Anis Fadhlina Izyani Sarker, Md. Zaidul Islam Ahmed, Qamar Uddin Md. Jaffri, Juliana Omar, Muhammad Nor Potential of untapped local species, “Chicha” (Stereospermum fimbriatum), as an alternative for skin infection treatment
description	Skin infection diseases are among the most common skin problems. Scientists believe that plants play a vital role in the public health. Stereospermum fimbriatum or “Chicha” used traditionally to cure stomachache, earache, itchy skin and postpartum illness. Therefore, this study was designed to investigate the phytochemical constituents of flowers, leaves, stem bark and twig of S. fimbriatum and their antimicrobial potential against eleven skin pathogens. Successive soxhlet extraction by n-hexane, dichloromethane and methanol was used. Disc diffusion, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were done to investigate their antimicrobial activities. Presence of terpenoid, steroid, flavonoid, saponin and tannin were observed in certain plant’s parts only. n-hexane extract of the S. fimbriatum’s stem bark (NS) possessed the most potent antibacterial activity especially against Staphylococcus epidermidis (16 mm±1), followed by MRSA (13.67 mm±0.58) and S. aureus (11.33 mm±0.58). All extracts exhibited no antimicrobial activity against Escherichia coli, Bacillus cereus, Pseudomonas aeruginosa, Proteus vulgaris, Enterococcus aerogenes, Candida albicans and Microsporum gypseum, except NS against S. pyogenes with weak antibacterial activity. The MIC analysis of susceptible strains resulted with a value of 1000 μg/mL. This study might lead to the discovery of novel agents with potential to treat dermal infections.
format	Conference or Workshop Item
author	Awang, Anis Fadhlina Izyani Sarker, Md. Zaidul Islam Ahmed, Qamar Uddin Md. Jaffri, Juliana Omar, Muhammad Nor
author_facet	Awang, Anis Fadhlina Izyani Sarker, Md. Zaidul Islam Ahmed, Qamar Uddin Md. Jaffri, Juliana Omar, Muhammad Nor
author_sort	Awang, Anis Fadhlina Izyani
title	Potential of untapped local species, “Chicha” (Stereospermum fimbriatum), as an alternative for skin infection treatment
title_short	Potential of untapped local species, “Chicha” (Stereospermum fimbriatum), as an alternative for skin infection treatment
title_full	Potential of untapped local species, “Chicha” (Stereospermum fimbriatum), as an alternative for skin infection treatment
title_fullStr	Potential of untapped local species, “Chicha” (Stereospermum fimbriatum), as an alternative for skin infection treatment
title_full_unstemmed	Potential of untapped local species, “Chicha” (Stereospermum fimbriatum), as an alternative for skin infection treatment
title_sort	potential of untapped local species, “chicha” (stereospermum fimbriatum), as an alternative for skin infection treatment
publisher	Fakulti Sains dan Teknologi, Universiti Kebangsaan Malaysia,
publishDate	2016
url	http://irep.iium.edu.my/54094/ http://irep.iium.edu.my/54094/ http://irep.iium.edu.my/54094/1/54094_Potential%20of%20untapped%20local%20species.pdf
first_indexed	2023-09-18T21:16:32Z
last_indexed	2023-09-18T21:16:32Z
_version_	1777411599690104832

Potential of untapped local species, “Chicha” (Stereospermum fimbriatum), as an alternative for skin infection treatment

Similar Items